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Veregen
Veregen (generic name: sinecatechins) is a topical medication derived from green tea leaves, used to treat external genital and perianal warts caused by human papillomavirus (HPV) in immunocompetent patients. It contains sinecatechins, which are a mixture of catechins, natural antioxidants found in green tea. Veregen helps clear warts by boosting the body’s immune response to HPV, leading to the destruction of the infected cells.
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Frequently Asked Questions
How long does it take for Veregen to work?
Warts may begin to disappear after a few weeks of treatment, but it can take up to 16 weeks for complete clearance. Continue using the ointment as prescribed until the warts are fully cleared.
Can I use Veregen if I am pregnant or breastfeeding?
The safety of Veregen in pregnant or breastfeeding women is not well established. Always consult your healthcare provider before using this medication if you are pregnant or breastfeeding.
What should I do if I miss a dose of Veregen?
If you miss a dose, apply it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and resume your regular schedule. Do not double up on doses.
Can Veregen be used internally (inside the vagina or anus)?
No, Veregen is for external use only and should not be applied inside the vagina, anus, or urethra.
How should I store Veregen?
Store Veregen at room temperature, away from excessive heat or moisture. Keep the tube tightly closed when not in use.
Comprehensive Drug Guide
How Does Veregen Work?
Veregen works by stimulating the body’s immune response to HPV infection, helping to attack and eliminate the virus-infected cells in the genital and perianal areas. The catechins in the ointment have antiviral, antioxidant, and immune-modulating properties, which help reduce the warts and prevent their recurrence.
Common Dosages
- 15% topical ointment
Typical Dosing
- Apply Veregen ointment three times daily to the affected areas using a thin layer. Treatment should continue until the warts are gone, for up to 16 weeks.
- Avoid covering the treated area with occlusive dressings or bandages.
Typical Dosing
FDA Approved Indications
- Topical treatment of external genital and perianal warts (condylomata acuminata) in immunocompetent patients aged 18 years and older.
Who Shouldn't Take Veregen?
- Known hypersensitivity to sinecatechins or any components of the ointment.
- Immunocompromised patients: Veregen is only approved for use in patients with healthy immune systems.
Advice From The Pharmacist
- Apply Veregen three times daily to clean, dry skin. Gently rub a thin layer of the ointment onto the warts.
- Do not wash the treated area immediately after applying the ointment. Allow the medication to absorb for several hours before washing the area.
- Avoid sexual contact while the ointment is on the skin, as it can weaken condoms or diaphragms and may spread the ointment to your partner.
- Do not use Veregen internally (inside the vagina, anus, or urethra). It is for external use only on the affected skin.
Side Effects of Veregen
Common Side Effects
- Redness or swelling at the application site
- Itching or burning
- Pain or discomfort at the treated area
- Skin irritation
Uncommon/Severe Side Effects
- Severe skin reactions, including blistering or ulceration of the treated area.
Allergic reactions (rash, swelling, difficulty breathing).
Risks and Warnings of Veregen
- Skin Reactions: Veregen can cause local skin reactions, such as redness, swelling, or itching. These reactions are usually mild but can sometimes be severe. If severe irritation occurs, contact your healthcare provider.
- Avoid Sun Exposure: Treated skin may become more sensitive to sunlight. Protect the area from excessive sun exposure, and use sunscreen or cover the area with clothing.
- Pregnancy and Breastfeeding: The safety of Veregen during pregnancy and breastfeeding has not been fully established. Consult your healthcare provider if you are pregnant or breastfeeding before using this medication.
Interactions with Veregen
Common Drug Interactions
- Avoid using other topical medications on the same areas being treated with Veregen, as this may increase irritation or reduce effectiveness.
- There are no known significant drug interactions with oral medications, but always inform your healthcare provider about all medications and supplements you are taking.
Alternatives to Veregen
- Imiquimod (Aldara): A topical immune response modifier used to treat genital warts.
- Podofilox (Condylox): A topical gel used to destroy genital warts.
- Cryotherapy: A procedure in which warts are frozen off using liquid nitrogen.
