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Urocit-K 15
Urocit-K 15 (generic name: potassium citrate) is a potassium supplement used to prevent the formation of certain types of kidney stones and to treat conditions associated with low urinary citrate levels. It works by increasing the levels of citrate in the urine, which helps neutralize acids and reduce the formation of crystals that can develop into stones. Urocit-K 15 is particularly effective in preventing calcium oxalate and uric acid stones.
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Frequently Asked Questions
How long does it take for Urocit-K 15 to work?
The effects on urinary citrate levels and pH can usually be seen within a few days to weeks. However, it may take longer for kidney stone prevention to become fully effective.
Can Urocit-K 15 be taken long-term?
Yes, Urocit-K can be taken long-term under a healthcare provider’s supervision. Regular monitoring of potassium levels and kidney function is essential for long-term use.
What should I do if I miss a dose of Urocit-K 15?
Take the missed dose as soon as you remember. If it is close to the time of your next dose, skip the missed dose and take the next one at the regular time. Do not double up on doses.
Can Urocit-K 15 cause kidney stones?
No, Urocit-K 15 is used to prevent kidney stones, particularly those caused by low urinary citrate levels. It helps make the urine less acidic and more alkaline, which reduces the risk of stone formation.
Should I follow a special diet while taking Urocit-K 15?
Your healthcare provider may recommend dietary adjustments, such as reducing salt intake or increasing fluid intake, to help prevent kidney stones and manage potassium levels. Follow your provider’s guidance on dietary and lifestyle changes.
Comprehensive Drug Guide
How Does Urocit-K 15 Work?
Urocit-K 15 works by increasing urinary pH (making the urine less acidic) and raising urinary citrate levels. This change in the chemical environment of the urine helps prevent the formation of certain types of kidney stones, especially calcium oxalate and uric acid stones. The increase in citrate helps bind calcium, reducing the risk of crystal formation.
Common Dosages
- 15 mEq extended-release oral tablets.
- The dosage and frequency of Urocit-K are individualized based on the patient’s needs and laboratory results.
Typical Dosing
- The typical dose is 30 to 90 mEq per day, divided into two to three doses.
- The dosing frequency and strength depend on the patient’s citrate levels and the severity of their condition.
- Tablets should be swallowed whole, not crushed, chewed, or broken, to maintain the extended-release effect.
Typical Dosing
FDA Approved Indications
- Prevention of calcium oxalate and uric acid kidney stones in patients with low urinary citrate (hypocitraturia).
- Management of renal tubular acidosis with calcium stones.
Who Shouldn't Take Urocit-K 15?
- Hyperkalemia (high levels of potassium in the blood).
- Chronic kidney disease or any condition that impairs potassium excretion.
- Dehydration, untreated Addison’s disease, or severe burns.
- Gastrointestinal obstruction, peptic ulcer disease, or delayed gastric emptying, as extended-release formulations can cause irritation or injury.
Advice From The Pharmacist
- Take Urocit-K 15 with meals and plenty of water to minimize the risk of stomach irritation.
- Do not crush, chew, or break the tablets, as this can lead to a rapid release of potassium, increasing the risk of side effects.
- Regular monitoring of potassium levels and urinary pH is essential while using Urocit-K to ensure that the treatment is effective and safe.
- Store the medication at room temperature, away from moisture and heat.
Side Effects of Urocit-K 15
Common Side Effects
- Nausea or upset stomach
- Diarrhea or loose stools
- Mild abdominal discomfort
Uncommon/Severe Side Effects
- High potassium levels (hyperkalemia), which can cause symptoms like muscle weakness, irregular heartbeat, or numbness.
- Gastrointestinal irritation or ulcers, especially if the tablet is crushed or chewed.
- Allergic reactions (rash, itching, swelling, difficulty breathing).
Risks and Warnings of Urocit-K 15
- Hyperkalemia Risk: Urocit-K 15 can cause high potassium levels in the blood, which can lead to life-threatening heart rhythm problems. Patients with kidney issues or those taking medications that increase potassium levels (such as ACE inhibitors or potassium-sparing diuretics) should be monitored closely.
- Gastrointestinal Risk: Extended-release potassium supplements can cause irritation or ulceration of the gastrointestinal tract, especially if the tablets are not swallowed whole. Always take the tablets with food and water.
- Kidney Function: Patients with impaired kidney function are at increased risk for potassium buildup, so kidney function should be monitored regularly while taking Urocit-K.
Interactions with Urocit-K 15
Common Drug Interactions
- Potassium-sparing diuretics (e.g., spironolactone, amiloride): These medications can increase potassium levels, raising the risk of hyperkalemia.
- ACE inhibitors or ARBs (e.g., lisinopril, losartan): These medications can also raise potassium levels, increasing the risk of hyperkalemia.
- Nonsteroidal anti-inflammatory drugs (NSAIDs): These drugs may reduce kidney function, increasing the risk of potassium buildup when taken with Urocit-K.
Alternatives to Urocit-K 15
- Potassium citrate (generic): Urocit-K is available in generic forms that provide the same active ingredient.
- Sodium bicarbonate: Used in some cases to alkalinize urine, though it may not provide the same citrate benefits as potassium citrate.
- Thiazide diuretics: Sometimes used in combination with potassium citrate to reduce calcium excretion in the urine.
