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Tri-Sprintec
Tri-Sprintec is a combination oral contraceptive pill used to prevent pregnancy. It contains two hormones: ethinyl estradiol (an estrogen) and norgestimate (a progestin). These hormones work together to prevent ovulation, thicken cervical mucus, and alter the lining of the uterus, making it difficult for sperm to reach the egg or for a fertilized egg to implant. Tri-Sprintec follows a triphasic dosing schedule, which provides varying hormone levels across three different phases of the menstrual cycle to mimic the body's natural hormone fluctuations.
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Frequently Asked Questions
Can Tri-Sprintec help with acne?
Yes, Tri-Sprintec is FDA-approved for the treatment of moderate acne in females aged 15 and older who also desire oral contraception.
What should I do if I miss a pill?
If you miss one active pill, take it as soon as you remember and take the next pill at your regular time. If you miss two or more active pills, refer to the instructions that come with your medication or consult your healthcare provider for guidance.
Can Tri-Sprintec cause weight gain?
Some women may experience slight weight gain due to fluid retention or other hormonal changes, but significant weight changes are uncommon.
Can I stop taking Tri-Sprintec whenever I want?
Yes, you can stop taking Tri-Sprintec at any time. However, if you stop taking it and do not use another form of contraception, you will be at risk for pregnancy. Consult your healthcare provider for guidance on alternative contraception options.
Does Tri-Sprintec protect against sexually transmitted infections (STIs)?
No, Tri-Sprintec does not protect against STIs. Condoms should be used in addition to oral contraceptives to reduce the risk of STIs.
Comprehensive Drug Guide
How Does Tri-Sprintec Work?
- Inhibiting ovulation: Prevents the release of an egg from the ovaries.
- Thickening cervical mucus: Makes it more difficult for sperm to travel through the cervix and fertilize an egg.
- Altering the uterine lining: Makes it less likely for a fertilized egg to implant in the uterus.
Common Dosages
- 21 active tablets with varying doses of estrogen and progestin.
- 7 inactive tablets (placebo), taken during the last week of the cycle.
Typical Dosing
- Take one active pill daily for 21 days, followed by one inactive pill daily for 7 days.
- After completing the 28-day cycle, start a new pack immediately, regardless of whether menstruation has started or ended.
Typical Dosing
FDA Approved Indications
- Contraception (prevention of pregnancy)
- Treatment of moderate acne in women aged 15 years and older who desire oral contraception and have started menstruating
Who Shouldn't Take Tri-Sprintec?
- A history of blood clots, stroke, or heart attack
- Uncontrolled hypertension
- Known or suspected breast cancer or other estrogen- or progestin-sensitive cancers
- Liver disease
- Pregnancy
Advice From The Pharmacist
- Take Tri-Sprintec at the same time every day to ensure consistent hormone levels and to maximize its contraceptive effectiveness.
- If you miss a pill, follow the instructions provided with your pack or consult your healthcare provider for guidance.
- Tri-Sprintec does not protect against sexually transmitted infections (STIs); using condoms is recommended for STI prevention.
- Store the pills at room temperature, away from moisture and heat, and ensure you begin each new pack on time to maintain contraceptive coverage.
Side Effects of Tri-Sprintec
Common Side Effects
- Nausea
- Breast tenderness
- Headache
- Weight changes
- Mood swings
Uncommon/Severe Side Effects
- Blood clots
- Stroke or heart attack
- High blood pressure
- Liver issues
Risks and Warnings of Tri-Sprintec
- Blood Clot Risk: Women who are over 35 and smoke have a higher risk of developing blood clots while using Tri-Sprintec. It is strongly recommended to stop smoking while taking this contraceptive.
- Hypertension: Tri-Sprintec may cause or worsen high blood pressure. Regular monitoring of blood pressure is recommended while taking this medication.
- Cancer Risk: Prolonged use of combination oral contraceptives may slightly increase the risk of breast cancer or liver tumors in some women.
Interactions with Tri-Sprintec
Common Drug Interactions
- Antibiotics: Certain antibiotics, such as rifampin, may reduce the effectiveness of Tri-Sprintec.
- Anticonvulsants: Some anticonvulsants can interfere with the efficacy of Tri-Sprintec and reduce its contraceptive effectiveness.
- St. John’s Wort: This herbal supplement may decrease the effectiveness of hormonal contraceptives.
- HIV medications: Some treatments for HIV may interact with Tri-Sprintec and decrease its effectiveness.
Alternatives to Tri-Sprintec
- Ortho Tri-Cyclen: A similar triphasic combination oral contraceptive with the same active ingredients as Tri-Sprintec.
- Loestrin Fe: A low-dose oral contraceptive option.
- Depo-Provera: A progestin-only injectable contraceptive given every three months.
- Intrauterine Device (IUD): A long-acting contraceptive option available in both hormonal and non-hormonal forms.
