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Tri-Nymyo
Tri-Nymyo is a combination oral contraceptive pill used to prevent pregnancy. It contains three active ingredients: ethinyl estradiol (an estrogen) and norgestimate (a progestin), delivered in varying doses across three phases of the menstrual cycle. Tri-Nymyo is designed to prevent ovulation, alter the uterine lining, and thicken cervical mucus, making it more difficult for sperm to reach the egg and for a fertilized egg to implant in the uterus. This triphasic regimen helps mimic the body’s natural hormonal fluctuations throughout the cycle.
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Frequently Asked Questions
Can Tri-Nymyo help with acne?
Yes, Tri-Nymyo is FDA-approved for the treatment of moderate acne in females aged 15 and older who desire oral contraception.
What should I do if I miss a pill?
If you miss one active pill, take it as soon as you remember and take the next pill at your regular time. If you miss two or more active pills, refer to the instructions that come with your medication or contact your healthcare provider for guidance.
Can I use Tri-Nymyo if I have a history of migraines?
If you have migraines, particularly those with aura, discuss this with your healthcare provider, as combination oral contraceptives may increase the risk of stroke in women with certain types of migraines.
Does Tri-Nymyo cause weight gain?
Some women may experience slight weight gain due to fluid retention or other hormonal changes while using Tri-Nymyo, but significant weight gain is uncommon.
Can I stop taking Tri-Nymyo whenever I want?
Yes, you can stop taking Tri-Nymyo at any time. However, if you stop taking it and do not switch to another form of contraception, you will be at risk for pregnancy. Consult your healthcare provider for guidance on alternative contraception options if you decide to stop.
Comprehensive Drug Guide
How Does Tri-Nymyo Work?
- Inhibiting ovulation: Preventing the release of an egg from the ovaries.
- Thickening cervical mucus: Making it more difficult for sperm to reach the uterus.
- Altering the uterine lining: Reducing the likelihood of implantation of a fertilized egg.
Common Dosages
- 21 active tablets with varying doses of estrogen and progestin, followed by
- 7 inactive tablets (placebo)
Typical Dosing
- Take one active pill daily for 21 days, followed by one inactive pill daily for 7 days.
- After completing the 28-day cycle, begin a new pack immediately, regardless of whether menstruation has started or ended.
Typical Dosing
FDA Approved Indications
- Contraception (prevention of pregnancy)
- Treatment of moderate acne in females aged 15 and older who have started menstruation and desire oral contraceptive therapy
Who Shouldn't Take Tri-Nymyo?
- A history of blood clots, stroke, or heart attack
- Uncontrolled hypertension
- Known or suspected breast cancer or other estrogen- or progestin-sensitive cancers
- Liver disease
- Pregnancy
Advice From The Pharmacist
- Take Tri-Nymyo at the same time every day to maintain consistent hormone levels and ensure maximum effectiveness.
- If you miss a pill, refer to the instructions provided with your pack to determine whether you need backup contraception.
- Tri-Nymyo does not protect against sexually transmitted infections (STIs); using condoms is recommended for STI prevention.
- Store your pills at room temperature, away from moisture and heat, and ensure you start each new pack on time.
Side Effects of Tri-Nymyo
Common Side Effects
- Nausea
- Breast tenderness
- Headache
- Weight gain
- Mood changes
Uncommon/Severe Side Effects
- Blood clots
- Stroke or heart attack
- High blood pressure
- Liver problems
Risks and Warnings of Tri-Nymyo
- Blood Clot Risk: Women who smoke and are over 35 years old have an increased risk of developing blood clots while using Tri-Nymyo. It is strongly recommended to stop smoking if using this contraceptive.
- Hypertension: Tri-Nymyo can cause or worsen high blood pressure. Your doctor may monitor your blood pressure while on this medication.
- Cancer Risk: Prolonged use of combination contraceptives may increase the risk of breast cancer or liver tumors in some women.
Interactions with Tri-Nymyo
Common Drug Interactions
- Antibiotics: Certain antibiotics, like rifampin, may reduce the effectiveness of Tri-Nymyo.
- Anticonvulsants: Some anticonvulsants can interfere with how Tri-Nymyo works, potentially reducing its contraceptive effectiveness.
- St. John's Wort: This herbal supplement may decrease the effectiveness of hormonal contraceptives.
- HIV Medications: Certain HIV treatments may interact with hormonal contraceptives, making them less effective.
Alternatives to Tri-Nymyo
- Ortho Tri-Cyclen: A similar combination oral contraceptive with the same active ingredients as Tri-Nymyo.
- Lo Loestrin Fe: A low-dose estrogen and progestin contraceptive pill.
- Depo-Provera: A progestin-only injectable contraceptive given every three months.
- Intrauterine Device (IUD): A long-acting contraceptive option available in both hormonal and non-hormonal forms.
