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Trandolapril
Trandolapril is an angiotensinconverting enzyme (ACE) inhibitor used to treat high blood pressure (hypertension) and heart failure. It works by relaxing blood vessels so blood can flow more easily, which helps lower blood pressure and reduces the strain on the heart. Some common side effects include dizziness, lightheadedness, and dry cough.
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Frequently Asked Questions
Can I take Trandolapril if I have diabetes?
Yes, but monitor your blood sugar levels as occasionally Trandolapril can affect them. Always consult your doctor for personalized advice.
Can Trandolapril cause weight gain?
Trandolapril is not known to cause weight gain. However, if you notice an increase in weight after starting this drug, discuss it with your doctor.
Is Trandolapril safe in pregnancy?
Trandolapril is not recommended during pregnancy. If you plan to become pregnant, discuss an alternative treatment with your doctor.
Should I avoid certain foods while taking Trandolapril?
Yes, avoid highpotassium food and salt substitutes. They might cause your potassium levels to go too high.
Comprehensive Drug Guide
How Does Trandolapril Work?
Trandolapril is an ACE inhibitor that blocks the production of Angiotensin II ? a chemical that can tighten blood vessels. This action allows blood to flow more easily, helping lower blood pressure.
What is Trandolapril Used For?
FDA indications: Trandolapril is usually prescribed for patients suffering from high blood pressure or heart failure.
Offlabel uses: It's also used to prevent kidney damage in people with type 2 diabetes.
Common Dosages
Tablets: 1mg, 2mg, 4mg
Typical Dosing
FDA Approved Indications
- For hypertension: Initial 1mg once a day; usual dosage range 24mg once a day, maximum 8mg daily.
- For heart failure: 1mg once daily, titrated to a target dose of 4mg once daily as tolerated by the patient.
Who Shouldn't Take Trandolapril?
- Have had an allergic reaction to any ACE inhibitor
- Pregnant or planning to become pregnant
- Suffer from kidney or liver disease
- Have a history of angioedema
- Have diabetes and you're taking a medication called Aliskiren
- Have certain types of heart conditions
- Have had a recent kidney transplant
- Have a history of stroke or blood clot
Advice From The Pharmacist
- Trandolapril is taken by mouth, usually once or twice a day.
- It can be taken with or without food
- Regular cardiovascular exercise can help improve the effectiveness of Trandolapril. Be sure to consult your doctor about the type and amount of exercise that is appropriate for you.
- Talk to your doctor if you're pregnant or planning to become pregnant. This drug can harm a developing fetus.
- Limit or avoid drinking alcohol while taking trandolapril. Alcohol can lower your blood pressure and may increase side effects.
- Drink plenty of water each day while you are taking this medication.
- Do not use salt substitutes or potassium supplements while taking trandolapril unless your doctor has told you to.
- Do not take this medication if you are allergic to any ACE inhibitors.
Side Effects of Trandolapril
Common Side Effects
- You might experience dizziness or lightheadedness.
- You might also suffer from a dry cough.
- Contact your doctor right away if you notice signs of high potassium blood levels, like muscle weakness or a slow, irregular heartbeat.
Risks and Warnings of Trandolapril
- Like every drug, Trandolapril isn't suitable for everyone. If you have had an allergic reaction to any ACE inhibitor in the past, you shouldn't use Trandolapril.
- Patients with a history of angioedema, kidney disease, or liver disease should also exercise caution.
- Using Trandolapril during pregnancy can harm a developing fetus, so it should be avoided if you are pregnant or planning to become pregnant.
- If you have certain types of heart conditions or if you have had a recent kidney transplant, you should discuss this with your healthcare provider before taking Trandolapril.
Interactions with Trandolapril
Common Drug Interactions
- Aliskiren
- NSAIDs (like ibuprofen, naproxen)
- Potassiumsparing diuretics (like spironolactone, triamterene)
- Other blood pressure medicines
Alternatives to Trandolapril
- Lisinopril
- Enalapril
- Ramipril
- Quinapril
- Perindopril
