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Tenoretic 100
Tenoretic 100 is a combination medication used to treat high blood pressure (hypertension). It contains two active ingredients: atenolol (a beta-blocker) and chlorthalidone (a thiazide diuretic). Atenolol helps reduce blood pressure by slowing the heart rate and reducing the workload on the heart, while chlorthalidone works by helping the kidneys remove excess salt and water from the body. Together, these actions help lower blood pressure and reduce the risk of heart attacks, strokes, and kidney problems.
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Frequently Asked Questions
How long does it take for Tenoretic 100 to start working?
It may take 1 to 2 weeks for Tenoretic 100 to show its full effects in lowering blood pressure. Continue taking the medication as prescribed, even if you do not feel immediate results.
Can I stop taking Tenoretic 100 if my blood pressure is under control?
No, you should not stop taking Tenoretic 100 without consulting your healthcare provider. Stopping the medication suddenly can lead to a rebound in blood pressure or heart issues.
What should I do if I miss a dose of Tenoretic 100?
Take the missed dose as soon as you remember. If it is close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time.
Can I take Tenoretic 100 with other blood pressure medications?
Yes, but you should only do so under your doctor’s supervision. Combining multiple blood pressure medications may lead to a greater reduction in blood pressure, so your doctor will monitor you closely for any side effects.
Is Tenoretic 100 safe for long-term use?
Yes, Tenoretic 100 is safe for long-term use when monitored by a healthcare provider. Regular blood pressure checks, kidney function tests, and electrolyte monitoring may be recommended to ensure continued safety.
Comprehensive Drug Guide
How Does Tenoretic 100 Work?
- Atenolol is a beta-blocker that works by blocking the action of adrenaline on beta receptors in the heart. This reduces heart rate, blood pressure, and the workload on the heart, helping to lower blood pressure.
- Chlorthalidone is a diuretic that increases the elimination of water and salt through the kidneys, helping to reduce blood volume and lower blood pressure.
Common Dosages
- Tenoretic 100: Contains 100 mg of atenolol and 25 mg of chlorthalidone.
- It is also available as Tenoretic 50, which contains 50 mg of atenolol and 25 mg of chlorthalidone.
Typical Dosing
- Adults: One tablet of Tenoretic 100 is usually taken once daily, with or without food.
- Adjustments: Your doctor may adjust the dosage based on your response to the medication and blood pressure control.
Typical Dosing
FDA Approved Indications
- Hypertension: Used to lower blood pressure in patients who require combination therapy for better blood pressure control.
Who Shouldn't Take Tenoretic 100?
- Bradycardia (slow heart rate)
- Heart block greater than the first degree
- Cardiogenic shock
- Uncompensated heart failure
- Known hypersensitivity to atenolol, chlorthalidone, or sulfonamide-derived drugs (chlorthalidone is a sulfonamide derivative)
- Severe kidney impairment
Advice From The Pharmacist
- Take Tenoretic 100 at the same time each day to maintain consistent levels of the medication in your body.
- Be aware that atenolol can cause dizziness or drowsiness, especially when you first start the medication or when your dose is increased. Avoid driving or operating heavy machinery until you know how the drug affects you.
- Do not stop taking Tenoretic 100 suddenly, as this can lead to a dangerous rise in blood pressure or heart problems, especially in people with heart disease. Always consult your doctor if you need to stop or adjust your dose.
- Monitor your potassium levels, as chlorthalidone can lower potassium levels, leading to muscle cramps or weakness.
- Stay hydrated, and avoid excessive salt in your diet to help the diuretic work more effectively.
Side Effects of Tenoretic 100
Common Side Effects
- Dizziness or lightheadedness
- Fatigue
- Nausea
- Muscle cramps
- Low blood pressure (hypotension)
Uncommon/Severe Side Effects
- Bradycardia (slow heart rate)
- Severe hypotension
- Electrolyte imbalances (low potassium, sodium, or magnesium levels)
- Worsening of heart failure symptoms
- Allergic reactions (rash, itching, swelling of the face or throat)
Risks and Warnings of Tenoretic 100
- Abrupt Discontinuation: Stopping Tenoretic 100 suddenly can cause rebound hypertension or angina. If discontinuation is necessary, the dose should be gradually reduced under medical supervision.
- Electrolyte Imbalance: The chlorthalidone component can cause low potassium and other electrolyte imbalances, leading to muscle cramps, fatigue, or abnormal heart rhythms.
- Bradycardia: Atenolol can slow the heart rate significantly, especially in individuals with underlying heart conditions.
- Kidney Function: Chlorthalidone can impair kidney function, especially in individuals with pre-existing kidney disease.
Interactions with Tenoretic 100
Common Drug Interactions
- NSAIDs: Nonsteroidal anti-inflammatory drugs (such as ibuprofen) can reduce the blood pressure-lowering effects of Tenoretic 100.
- Diabetes medications: Atenolol may mask the symptoms of low blood sugar (hypoglycemia), and chlorthalidone may increase blood sugar levels.
- Calcium channel blockers: Combining beta-blockers with calcium channel blockers (such as verapamil) can lead to an excessive slowing of the heart rate or worsening of heart failure.
- Potassium supplements or potassium-sparing diuretics: Using these with chlorthalidone can lead to an imbalance in potassium levels.
Alternatives to Tenoretic 100
- Lisinopril-HCTZ: A combination of an ACE inhibitor and a diuretic, used to treat high blood pressure.
- Losartan-HCTZ: An ARB combined with a thiazide diuretic, offering a different mechanism of action for hypertension treatment.
- Metoprolol-HCTZ: Another beta-blocker combined with a thiazide diuretic for managing high blood pressure.
- Amlodipine: A calcium channel blocker that can be used as an alternative if beta-blockers are not suitable.
