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Temovate
Temovate (generic name: clobetasol propionate) is a topical corticosteroid used to treat a variety of skin conditions, including psoriasis, eczema, and dermatitis. It works by reducing inflammation, swelling, and itching associated with skin disorders. Temovate is a high-potency steroid and is usually prescribed for short-term use to manage severe symptoms.
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Frequently Asked Questions
How long can I use Temovate?
Temovate should not be used for longer than 2 weeks at a time without a break. Long-term use increases the risk of skin thinning and other side effects.
Can I use Temovate on my face?
Temovate should generally be avoided on the face, as the skin there is thinner and more prone to side effects. Use only under the supervision of your doctor if necessary.
What should I do if I miss a dose of Temovate?
Apply the missed dose as soon as you remember. If it is close to the time for your next dose, skip the missed dose and apply the next one as scheduled. Do not double the dose.
Can I stop using Temovate suddenly?
If you have been using Temovate for a prolonged period, you should not stop abruptly. Your doctor may recommend tapering off the use of the medication to prevent a flare-up of your skin condition.
Is Temovate safe for children?
Temovate can be used in children but with caution and under strict medical supervision. Children are more susceptible to side effects, including growth suppression and adrenal insufficiency, due to the stronger potency of the drug.
Comprehensive Drug Guide
How Does Temovate Work?
Clobetasol propionate works by inhibiting the release of inflammatory substances in the skin, thereby reducing redness, swelling, and itching. It also helps to suppress immune system activity in the affected area, which helps reduce the severity of the skin condition.
What is Temovate Used For?
Common Dosages
- 0.05% cream, ointment, gel, lotion, or foam
Typical Dosing
- For psoriasis or dermatitis: A thin layer of Temovate is applied once or twice daily to the affected area for up to 2 weeks. Treatment duration may vary depending on the condition and severity, but long-term use is not recommended due to the risk of side effects.
- For scalp conditions: The shampoo or foam is applied to the affected area of the scalp once daily and left in place for a specified time before rinsing.
Typical Dosing
FDA Approved Indications
- Psoriasis (particularly plaque psoriasis)
- Atopic dermatitis (eczema)
- Seborrheic dermatitis
- Contact dermatitis
- Other skin conditions that respond to corticosteroid therapy
Off-Label Uses
Who Shouldn't Take Temovate?
- Hypersensitivity to clobetasol or any component of the formulation
- Skin infections (e.g., fungal or bacterial infections) that have not been treated
- Rosacea or perioral dermatitis (use of potent corticosteroids in these conditions can worsen symptoms)
Advice From The Pharmacist
- Apply a thin layer of Temovate to the affected area, and avoid using it on broken skin or large areas of the body unless directed by your doctor.
- Do not cover or bandage the treated area unless instructed to do so by your doctor, as this can increase absorption and the risk of side effects.
- Use Temovate for the shortest duration necessary to control symptoms. Long-term use can increase the risk of skin thinning, stretch marks, and other side effects.
- Avoid using Temovate on the face, groin, or underarms unless specifically directed by your healthcare provider.
- Wash your hands thoroughly after applying Temovate to avoid accidental contact with your eyes or other sensitive areas.
Side Effects of Temovate
Common Side Effects
- Skin irritation or redness at the application site
- Dry or cracking skin
- Burning or stinging sensation
- Thinning of the skin (with long-term use)
- Stretch marks (striae)
Uncommon/Severe Side Effects
- Skin atrophy (thinning of the skin)
- Systemic corticosteroid effects: If absorbed in large amounts, Temovate can cause symptoms like weight gain, mood changes, or high blood sugar levels.
- Allergic reactions, such as rash, swelling, or difficulty breathing (rare)
Risks and Warnings of Temovate
- Skin Thinning: Long-term or excessive use of Temovate can lead to thinning of the skin, stretch marks, and increased risk of infections. It should not be used for more than 2 weeks unless specifically directed by a healthcare provider.
- HPA Axis Suppression: When used in large quantities or over large areas of the body, clobetasol can be absorbed into the bloodstream and suppress the body’s natural production of corticosteroids. This can lead to a condition known as adrenal insufficiency, which may require tapering off the medication rather than stopping abruptly.
- Use in Children: Temovate should be used with caution in children, as they are more prone to systemic side effects, including growth suppression.
Interactions with Temovate
Common Drug Interactions
- Other corticosteroids: Using multiple corticosteroid products at the same time can increase the risk of side effects, including skin thinning and HPA axis suppression.
- Occlusive dressings: Covering the treated area with bandages or dressings can increase absorption and enhance the risk of systemic side effects.
Alternatives to Temovate
- Triamcinolone Acetonide: A medium-potency corticosteroid often used for less severe skin conditions.
- Betamethasone Dipropionate: Another high-potency topical corticosteroid for treating inflammatory skin conditions.
- Hydrocortisone: A low-potency corticosteroid available over the counter for mild skin irritations and rashes.
- Calcipotriene (Dovonex): A non-steroidal topical treatment for psoriasis.
