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prednisoLONE-Bromfenac
Prednisolone-bromfenac is a combination medication that combines prednisolone acetate, a corticosteroid, with bromfenac, a nonsteroidal anti-inflammatory drug (NSAID). This combination is primarily used in the treatment of inflammation and pain following cataract surgery and for other inflammatory conditions affecting the eyes. The synergistic action of the two agents helps to effectively reduce inflammation, pain, and discomfort.
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Frequently Asked Questions
How quickly does prednisolone-bromfenac start to work?
Patients may begin to notice relief from inflammation and pain within a few hours of application, but complete resolution may take several days depending on the condition being treated.
Can I stop using prednisolone-bromfenac suddenly?
It is generally safe to discontinue prednisolone-bromfenac as directed; however, consult your healthcare provider if you have been using it for an extended period.
Are there any specific dietary restrictions while using prednisolone-bromfenac?
There are no specific dietary restrictions associated with this medication.
What should I do if I miss a dose of prednisolone-bromfenac?
If you miss a dose, take it as soon as you remember. If it’s close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not double up on doses.
Is prednisolone-bromfenac safe for long-term use?
While effective for managing postoperative inflammation, this combination is generally intended for short-term use. Long-term use should be monitored by a healthcare provider to assess for potential side effects, especially increased intraocular pressure or cataracts. Regular follow-ups are important to evaluate treatment efficacy and safety.
Comprehensive Drug Guide
How Does prednisoLONE-Bromfenac Work?
- Prednisolone Acetate: Works by inhibiting the inflammatory response in the eye by reducing the production of inflammatory mediators, leading to decreased redness, swelling, and pain.
- Bromfenac: Inhibits cyclooxygenase (COX) enzymes, which are responsible for the production of prostaglandins, leading to reduced inflammation and pain.
The combination of these two medications enhances overall effectiveness in managing postoperative inflammation and discomfort.
Common Dosages
- Ophthalmic solution: Common concentrations include 0.07% of prednisolone acetate and 0.09% of bromfenac.
Typical Dosing
- The usual dosing regimen involves instilling one drop in the affected eye(s) twice daily, starting 1 day before surgery and continuing for up to 14 days postoperatively, or as directed by a healthcare provider.
Typical Dosing
FDA Approved Indications
- Treatment of inflammation and pain associated with cataract surgery.
Who Shouldn't Take prednisoLONE-Bromfenac?
- Known hypersensitivity to either prednisolone acetate, bromfenac, or any components of the formulation.
- Viral infections of the eye, such as herpes simplex keratitis.
- Fungal infections or tuberculosis of the eye.
Advice From The Pharmacist
- Instruct patients on the proper technique for administering eye drops to ensure effective delivery of the medication to the affected eye.
- Advise patients to avoid touching the dropper tip to any surface, including the eye, to prevent contamination.
- Encourage patients to report any worsening symptoms, such as increased redness, pain, or changes in vision.
Side Effects of prednisoLONE-Bromfenac
Common Side Effects
- Eye irritation or burning sensation upon application
- Dryness of the eye
- Blurred vision
- Rash or redness around the application site
Uncommon/Severe Side Effects
- Severe allergic reactions (such as rash, itching, or difficulty breathing)
- Increased intraocular pressure leading to glaucoma
- Cataract formation with long-term use
Risks and Warnings of prednisoLONE-Bromfenac
- Intraocular Pressure: Prolonged use of corticosteroids can lead to increased intraocular pressure; patients should be monitored regularly for glaucoma.
- Infection Risk: Corticosteroids can mask the signs of infection; any signs of worsening conditions should be evaluated promptly.
Interactions with prednisoLONE-Bromfenac
Common Drug Interactions
- Other Ophthalmic Medications: When using multiple eye drops, patients should be advised to wait at least 5 minutes between different medications to avoid dilution and ensure effectiveness.
Alternatives to prednisoLONE-Bromfenac
- Other Topical Corticosteroids: Such as dexamethasone or fluorometholone, may be considered for similar indications depending on the severity of the condition.
- Other NSAIDs: Such as ketorolac or diclofenac, may be used for postoperative pain and inflammation.
