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Phenergan
Promethazine is an antihistamine medication, often combined with other drugs to reduce symptoms of allergies, motion sickness, and nausea. It's also used as a sedative or sleep aid due to its calming effects. Some common side effects include dizziness, dry mouth, and drowsiness. Remember, your healthcare provider will prescribe this medication only if they believe the benefits exceed these challenges.
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Frequently Asked Questions
Can I take Promethazine if I have glaucoma?
Not advised. Promethazine may increase the pressure within your eyes, making glaucoma worse.
Does Promethazine interact negatively with alcohol?
Yes, it enhances the sedative effects of alcohol which can increase your risk of drowsiness and dizziness.
Should I take Promethazine before traveling?
Yes. One effective use of promethazine is as a preventive measure against motion sickness during travel.
What should I do if I miss a dose?
Take it as soon as you remember but never take extra doses.
Can I just stop taking Promethazine after my symptoms are gone?
Abruptly stopping can cause withdrawal symptoms. Always follow your doctor's directions about how to stop taking this medicine.
Comprehensive Drug Guide
How Does Phenergan Work?
Promethazine is an antagonist to histamine H1 receptors. It blocks the actions of histamines produced during allergic reactions while exhibiting a significant anticholinergic and sedative effect.
What is Phenergan Used For?
FDA indications: Promethazine is used for allergic reactions, motion sickness, nausea, and vomiting, and as a sedative or sleep aid.
Off-label uses: It can also be used in treating migraines and specific symptoms related to the common cold
Common Dosages
Tablets: 12.5mg, 25mg, 50mg
Oral solution: 6.25mg/5mL
Typical Dosing
FDA Approved Indications
- For allergic reactions: 25mg to start, then 12.5mg to 25mg every 4-6 hours as needed.
- For motion sickness: 25mg to deal with the symptom, repeating the same dose after 24 hours if necessary.
- For nausea and vomiting: 12.5mg to 25mg, taken every 4-6 hours.
Who Shouldn't Take Phenergan?
- Persons are hypersensitive to promethazine or other phenothiazines.
- Children under two years.
- In a coma or suffering from severe central nervous system depression.
- If you have a history of sleep apnea, seizure disorders, or asthma.
- Pregnant, intending to get pregnant, or breastfeeding (without doctor consultation).
- Suffering from glaucoma or severe cardiovascular disorders.
Advice From The Pharmacist
- Promethazine can make you drowsy, so avoid operating heavy machinery.
- Limit alcohol consumption as it can enhance promethazine's drowsiness effect.
- This medication can result in sun sensitivity, so wear protective clothing and use sunscreen when outdoors.
- Do not stop medication abruptly as it may cause withdrawal symptoms.
- Consult a doctor before giving this medication to a child.
Side Effects of Phenergan
Common Side Effects
- You might feel light-headed or drowsy.
- Your mouth may feel dry.
- You may feel dizzy or faint when standing up.
Uncommon/Severe Side Effects
- Rare side effects:
- You might have convulsions or involuntary muscle movements.
- You may experience a fast or irregular heartbeat.
- Your skin might become unusually sensitive to sunlight.
- Severe side effects:
- Seek immediate medical attention if you have symptoms of serious allergic reactions like rash, itching, or swelling of the face/tongue/throat, severe dizziness, or trouble breathing.
- Symptoms of serotonin syndrome include fast heartbeat, hallucinations, loss of coordination, severe nausea/vomiting/diarrhea, and twitching muscles.
- A very serious side effect could be a condition called Neuroleptic Malignant Syndrome (NMS) characterized by fever, rigid muscles, confusion, sweating, and fast or irregular heartbeats.
Risks and Warnings of Phenergan
- Promethazine may cause severe breathing problems or even death in some children. Therefore, it must not be used in children under two years old.
- It may increase your risk of seizures or make any seizure disorders you have worse.
- Promethazine can increase the risk of dizziness, light-headedness, or fainting, particularly during the initial days of use.
- Those with a history of blood disorders or at risk of blocked stomach/intestines should be cautious.
- It poses the risk of Neuroleptic Malignant Syndrome (NMS) ? symptoms include fever, stiff muscles, confusion, abnormal thinking, fast or irregular heartbeat, and increased sweating.
Interactions with Phenergan
Common Drug Interactions
- Sedatives
- Tranquilizers
- Anesthetics
- Antihistamines
- Antipsychotics
Common Food Interactions
- Limit alcoholic beverages due to increased drowsiness.
- Avoid excessive sun exposure.
Alternatives to Phenergan
- Diphenhydramine
- Hydroxyzine
- Chlorpheniramine
- Cyproheptadine
- Loratadine
