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hydrOXYzine HCl
Hydroxyzine is an antihistamine medication used frequently to treat itching caused by allergies. It is also used to control nausea and vomiting, to help with anxiety and tension, or to help you feel relaxed before or after surgery. Some common side effects include drowsiness, dry mouth, and dizziness, but the comfort brought by relief from allergic reactions usually outweighs these minor side effects.
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Frequently Asked Questions
Can I take Hydroxyzine while pregnant?
Hydroxyzine is classified as Category C for pregnancy, meaning it should be used only if the potential benefits justify the potential risks to the fetus. Always consult your healthcare provider.
Can you feel high from hydroxyzine?
There have been reported cases of drug misuse and overdose which may lead to feeling "high". However, misuse or overuse can lead to severe side effects and must be avoided.
What happens if I miss a dose of Hydroxyzine?
In case you forget to take a dose, take it as soon as you remember. If it is time for your next dose, continue with your regular scheduling.
I feel very sleepy after taking Hydroxyzine, what should I do?
Drowsiness is a common side effect of Hydroxyzine. If it is excessive and is interfering with your day-to-day activities, talk to your doctor.
Does Hydroxyzine interact with alcohol?
Yes, combining alcohol with hydroxyzine can increase the side effects of hydroxyzine, particularly drowsiness and impaired motor functions. It is best to avoid it.
Comprehensive Drug Guide
How Does hydrOXYzine HCl Work?
Hydroxyzine acts as an antagonist on central and peripheral H1 histamine receptors and exhibits extensive sedative and anticholinergic properties.
What is hydrOXYzine HCl Used For?
FDA indications: Hydroxyzine is used for symptomatic relief of anxiety and tension associated with psychoneurosis and as an adjunct in organic disease states in which anxiety is manifested. It is also useful in the management of pruritus due to allergic conditions such as chronic urticaria and atopic and contact dermatoses and in histamine-mediated pruritus.
Off-label uses: Hydroxyzine has been used off-label for nausea, vomiting, and alcohol withdrawal.
Common Dosages
Tablets: 10mg, 25mg, 50mg
Syrup: 10mg/5mL
Typical Dosing
FDA Approved Indications
- For FDA-approved indications:
- Anxiety and tension: 50-100mg every four to six hours
- Allergy-induced itchiness: 25mg three to four times per day
Off-Label Uses
- Off-label uses:
- Nausea and vomiting: 25-100mg every four to six hours
Who Shouldn't Take hydrOXYzine HCl?
- Those with known hypersensitivity to hydroxyzine
- Patients with a known QT interval prolongation
- Patients who have recently had a heart attack
Advice From The Pharmacist
- Try to take this medication at the same time each day to ensure a steady level in your body.
- This medicine may cause drowsiness. If affected, do not operate machinery or drive.
- Avoid alcohol while taking this medication as it can increase the drowsiness caused by the medication.
- It's best to avoid consuming grapefruit juice while taking this medication. Grapefruit can increase the amount of certain medications in your bloodstream.
- As with all medications, if you are pregnant, planning to become pregnant, or are breastfeeding, consult your healthcare provider before starting this medicine.
Side Effects of hydrOXYzine HCl
Common Side Effects
- Common side effects:
- Drowsiness
- Dry mouth
- Headache
Uncommon/Severe Side Effects
- Rare side effects:
- Tremor
- Convulsions
- Changes in vision
- Severe side effects:
- Unwanted twitching in your face or neck - this is a serious sign and needs medical attention.
- Yellowing skin or eyes, i.e., signs of liver problems.
Risks and Warnings of hydrOXYzine HCl
- Patients with a history of seizures, long QT syndrome, asthma, glaucoma, high blood pressure, heart disease, stomach ulcer, blockage in the stomach or intestines, or thyroid disorder should consult their doctor before starting Hydroxyzine.
- Avoid using Hydroxyzine if you're allergic to cetirizine (Zyrtec) or levocetirizine (Xyzal).
- The elderly are more sensitive to side effects, specifically drowsiness, confusion, constipation, or trouble urinating.
Interactions with hydrOXYzine HCl
Common Drug Interactions
- Alcohol
- CNS depressants like barbiturates, benzodiazepines
- Antidepressants
Alternatives to hydrOXYzine HCl
- Diphenhydramine
- Loratadine
- Fexofenadine
- Doxepin
- Promethazine
