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Ovide

Ovide (malathion) is a topical insecticide primarily used for the treatment of head lice infestations. It works by killing lice and their eggs (nits) to effectively eliminate the infestation.



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Frequently Asked Questions

How quickly does Ovide work?
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Ovide typically begins to kill lice upon application, but it may take up to 12 hours for maximum effectiveness.

Can I use Ovide if I have colored or permed hair?
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Yes, but consult your healthcare provider for specific recommendations, as some treatments may affect the color or texture of treated hair.

What should I do if I miss a dose?
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If you miss an application, apply it as soon as you remember. If it’s close to the time for your next scheduled application, skip the missed application and continue with your regular schedule.

Is Ovide safe during pregnancy?
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Consult your healthcare provider before using Ovide during pregnancy to evaluate potential risks and benefits.

What are the signs of serious side effects to watch for?
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Monitor for signs of severe allergic reactions or significant irritation, and seek immediate medical attention if these occur.

Comprehensive Drug Guide

How Does Ovide Work?

Malathion is an organophosphate that works by inhibiting the enzyme acetylcholinesterase. This leads to an accumulation of acetylcholine at the neuromuscular junction, causing paralysis and death in lice.



Common Dosages

  • Topical lotion: Usually available in a 0.5% concentration.

Typical Dosing

  • Adults and Children (6 years and older): Apply Ovide to dry hair, ensuring that the lotion is thoroughly saturated. Leave it on for 8 to 12 hours, then rinse off with water. A second application may be needed after 7 to 9 days if live lice are still present.


Typical Dosing

FDA Approved Indications

  • Treatment of head lice infestations in patients aged 6 years and older.


Who Shouldn't Take Ovide?

  • Known hypersensitivity to malathion or any component of the formulation.
  • Open sores or lesions on the scalp.


Advice From The Pharmacist

  • Apply Ovide only as directed, and do not exceed the recommended duration of application.
  • Avoid contact with eyes and mucous membranes; if contact occurs, rinse thoroughly with water.
  • Wash clothing, bedding, and personal items in hot water to prevent re-infestation.


Side Effects of Ovide

Common Side Effects

  • Local irritation (itching, burning, or redness)
  • Dry hair or scalp


Uncommon/Severe Side Effects

  • Severe allergic reactions (rash, itching, swelling)
  • Eye irritation if the lotion comes into contact with the eyes


Risks and Warnings of Ovide

  • Flammability: Ovide is flammable; avoid using it near open flames or heat sources.
  • Caution in Sensitive Populations: Use with caution in individuals with asthma or respiratory conditions.


Interactions with Ovide

Common Drug Interactions

  • Other Topical Products: Avoid using other topical products on the hair and scalp during treatment to prevent irritation or reduced effectiveness.


Alternatives to Ovide

  • Other Lice Treatments: Such as permethrin or pyrethrin-based products for treating head lice.