You're not logged in. Please log in to earn stock or Bitcoin rewards on your prescription purchase.
Onzetra Xsail
Onzetra Xsail (sumatriptan) is a nasal spray used for the acute treatment of migraine attacks with or without aura in adults. It is part of the triptan class of medications, which are specifically designed to alleviate migraine symptoms by targeting serotonin receptors in the brain.
Rx. Enter your prescription
How would you like to get your prescription? Select an option
Pharmacy pickup
Select from 35,000 pharmacies
Free two-day delivery
Coming soon!
Find a pharmacy near you. Enter your ZIP code
Are you a member? Sign up or log in.
Members have saved
$NaN
using our savings card for instant savings.
Don't pay full retail price and miss out on potential savings. Try it now—you have nothing to lose!
NaNM
worth of Satoshi has been rewarded to our members.
Everyone who signs up enjoys the benefits of earning FREE Bitcoin with every purchase.
How much Bitcoin can you earn with Onzetra Xsail ?
The potential for Bitcoin rewards to increase and appreciate in value is a possibility to consider, which may occur over time.
See the value of your savings today
Today's Value
1 Bitcoin = $NaN
Bitcoin (BTC)
...
USD
$NaN
Adjust Bitcoin's potential value to see how much it could be worth
Potential Value
1 Bitcoin =
Bitcoin (BTC)
...
USD
$NaN
Frequently Asked Questions
How quickly does Onzetra Xsail work?
Many patients may experience relief within 15 to 30 minutes after using the nasal spray.
Can I use Onzetra Xsail for prevention of migraines?
No, Onzetra Xsail is intended for the acute treatment of migraines, not for prevention.
What should I do if I miss a dose?
If you miss a dose during a migraine attack, take it as soon as you remember, but do not exceed the maximum recommended dosage within a 24-hour period.
Is Onzetra Xsail safe during pregnancy?
Consult your healthcare provider before using Onzetra Xsail during pregnancy to evaluate potential risks and benefits.
What are the signs of serious side effects to watch for?
Monitor for severe allergic reactions, chest pain, or unusual symptoms, and seek immediate medical attention if these occur.
Comprehensive Drug Guide
How Does Onzetra Xsail Work?
Onzetra Xsail works by selectively agonizing serotonin (5-HT) receptors, specifically the 5-HT1B and 5-HT1D receptors in the brain. This action leads to vasoconstriction of dilated cranial blood vessels and inhibition of pro-inflammatory neuropeptide release, effectively alleviating migraine symptoms.
Common Dosages
- Nasal spray: Each device contains 5 mg of sumatriptan in a single-use dose.
Typical Dosing
- Adults: The recommended dose is 1 spray (5 mg) into one nostril at the onset of a migraine. A second dose may be administered after 2 hours if the migraine symptoms do not improve, but the total daily dose should not exceed 20 mg (4 sprays).
Typical Dosing
FDA Approved Indications
- The acute treatment of migraine attacks in adults.
Who Shouldn't Take Onzetra Xsail?
- Known hypersensitivity to sumatriptan or any component of the formulation
- History of ischemic heart disease, cerebrovascular accident (stroke), or severe hepatic impairment
Advice From The Pharmacist
- Use Onzetra Xsail as soon as migraine symptoms begin for optimal effectiveness.
- Ensure proper administration technique; spray into one nostril while keeping the other nostril closed.
- Monitor for any side effects, and inform your healthcare provider if you experience any concerning symptoms.
Side Effects of Onzetra Xsail
Common Side Effects
- Nasal discomfort
- Altered taste
- Dizziness
- Drowsiness
Uncommon/Severe Side Effects
- Severe allergic reactions (rash, itching, swelling)
- Cardiovascular events (chest pain, tightness)
Risks and Warnings of Onzetra Xsail
- Cardiovascular Risk: Caution is advised in patients with cardiovascular risk factors due to the potential for vasoconstriction.
- Medication Overuse: Frequent use of triptans can lead to medication-overuse headaches; consult your healthcare provider if you find yourself needing to use it often.
Interactions with Onzetra Xsail
Common Drug Interactions
- Other Serotonergic Medications: Use caution when combining with other medications that affect serotonin levels, such as SSRIs or SNRIs, to avoid serotonin syndrome.
- Other Triptans: Avoid using other triptans within 24 hours of administering Onzetra Xsail.
Alternatives to Onzetra Xsail
- Other Triptans: Such as rizatriptan or eletriptan for acute migraine treatment.
- Non-Triptan Medications: Over-the-counter options like ibuprofen or acetaminophen may also be used, depending on the individual situation.
