You're not logged in. Please log in to earn stock or Bitcoin rewards on your prescription purchase.
Ondansetron HCl
Ondansetron HCl is an antiemetic medication used primarily to prevent nausea and vomiting caused by chemotherapy, radiation therapy, and surgery. It works by blocking the action of serotonin, a neurotransmitter that can trigger nausea and vomiting, particularly in the gastrointestinal tract and the brain.
Rx. Enter your prescription
How would you like to get your prescription? Select an option
Pharmacy pickup
Select from 35,000 pharmacies
Free two-day delivery
Coming soon!
Find a pharmacy near you. Enter your ZIP code
Are you a member? Sign up or log in.
Members have saved
$NaN
using our savings card for instant savings.
Don't pay full retail price and miss out on potential savings. Try it now—you have nothing to lose!
NaNM
worth of Satoshi has been rewarded to our members.
Everyone who signs up enjoys the benefits of earning FREE Bitcoin with every purchase.
How much Bitcoin can you earn with Ondansetron HCl ?
The potential for Bitcoin rewards to increase and appreciate in value is a possibility to consider, which may occur over time.
See the value of your savings today
Today's Value
1 Bitcoin = $NaN
Bitcoin (BTC)
...
USD
$NaN
Adjust Bitcoin's potential value to see how much it could be worth
Potential Value
1 Bitcoin =
Bitcoin (BTC)
...
USD
$NaN
Frequently Asked Questions
How quickly does Ondansetron HCl work?
Ondansetron typically begins to work within 30 minutes of oral administration.
Can I take Ondansetron HCl with food?
Yes, Ondansetron can be taken with or without food.
What should I do if I miss a dose?
If you miss a dose, take it as soon as you remember. If it’s close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not double up doses.
Are there any dietary restrictions while using Ondansetron HCl?
There are no specific dietary restrictions while using Ondansetron HCl.
Is Ondansetron HCl safe during pregnancy or breastfeeding?
Consult your healthcare provider if you are pregnant or breastfeeding to discuss the risks and benefits of using Ondansetron HCl during these periods.
Comprehensive Drug Guide
How Does Ondansetron HCl Work?
Ondansetron works by selectively antagonizing the 5-HT3 receptors in the central nervous system and gastrointestinal tract. By blocking serotonin’s action at these sites, ondansetron effectively reduces the sensation of nausea and prevents vomiting.
What is Ondansetron HCl Used For?
Common Dosages
- Tablets: Common strengths include 4 mg and 8 mg.
- Orally Disintegrating Tablets: Available in 4 mg and 8 mg.
- Injection: 2 mg/mL for intravenous use.
Typical Dosing
- For chemotherapy: The usual dose is 8 mg taken orally 30 minutes before chemotherapy, followed by an additional dose every 8 hours for 1 to 2 days after treatment.
- For postoperative nausea: The recommended dose is 16 mg given orally 1 hour before anesthesia.
- For radiation: The typical dose is 8 mg taken orally 1 to 2 hours before treatment.
Typical Dosing
FDA Approved Indications
- Chemotherapy-Induced Nausea and Vomiting: for the prevention of nausea and vomiting associated with highly emetogenic chemotherapy.
- Postoperative Nausea and Vomiting: for the prevention of nausea and vomiting following surgery.
- Radiation-Induced Nausea and Vomiting: for the prevention of nausea and vomiting associated with radiation therapy.
Off-Label Uses
Who Shouldn't Take Ondansetron HCl?
- Known hypersensitivity to ondansetron or any component of the formulation.
- A history of congenital long QT syndrome or patients taking other medications that can prolong the QT interval.
Advice From The Pharmacist
- Take Ondansetron HCl exactly as prescribed, and do not exceed the recommended dose.
- If using the orally disintegrating tablet, allow it to dissolve on your tongue without chewing.
- Monitor for any signs of allergic reactions, such as rash or difficulty breathing, and report them to your healthcare provider.
Side Effects of Ondansetron HCl
Common Side Effects
- Headache
- Dizziness
- Constipation
- Fatigue
Uncommon/Severe Side Effects
- Severe allergic reactions (rash, itching, swelling)
- QT prolongation leading to serious heart rhythm problems.
Risks and Warnings of Ondansetron HCl
- Cardiac Risks: Monitor patients with existing cardiac conditions, as ondansetron can prolong the QT interval.
- Serotonin Syndrome: Caution is advised if used with other medications that increase serotonin levels.
Interactions with Ondansetron HCl
Common Drug Interactions
- CNS Depressants: Use with caution when combined with sedatives or other CNS depressants.
- Medications Affecting QT Interval: Caution is warranted if used with other drugs known to prolong the QT interval.
Alternatives to Ondansetron HCl
- Other Antiemetics: Such as granisetron or palonosetron for similar indications.
- Dopamine Antagonists: Such as metoclopramide for nausea and vomiting management.
