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Nourianz
Nourianz (amantadine) is a medication used primarily for the treatment of Parkinson's disease and drug-induced extrapyramidal symptoms. It is also indicated for the prevention and treatment of influenza A virus infections. Nourianz works by modulating dopamine transmission in the brain, which helps alleviate symptoms of Parkinson's disease.
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Frequently Asked Questions
How quickly does Nourianz work?
Patients may start to notice improvements in Parkinson's symptoms within a few days to a week, but optimal effects may take longer.
Can I take Nourianz with food?
Yes, Nourianz can be taken with or without food. Taking it with food may help reduce gastrointestinal side effects.
What should I do if I miss a dose?
If you miss a dose, take it as soon as you remember. If it’s close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not double up.
Is Nourianz safe during pregnancy?
Consult your healthcare provider before using Nourianz during pregnancy to evaluate potential risks and benefits.
What are the signs of serious side effects to watch for?
Monitor for signs of severe allergic reactions or significant changes in mood or behavior, and seek immediate medical attention if these occur.
Comprehensive Drug Guide
How Does Nourianz Work?
Nourianz works by increasing the release of dopamine and inhibiting its reuptake in the brain. It also has NMDA receptor antagonist properties, which may help to reduce the symptoms of Parkinson's disease by enhancing dopaminergic transmission.
Common Dosages
- Tablets: Common strengths include 100 mg.
Typical Dosing
- For Parkinson's disease: The usual recommended starting dose is 100 mg once daily, which may be adjusted based on clinical response. The maximum dose is typically 400 mg per day.
- For influenza: Dosing varies, and it is usually administered for a limited duration during an outbreak.
Typical Dosing
FDA Approved Indications
- Treatment of Parkinson's disease as an adjunct to other therapies.
- Prevention and treatment of influenza A virus infections.
Who Shouldn't Take Nourianz?
- Known hypersensitivity to amantadine or any component of the formulation.
- Severe renal impairment without dosage adjustment.
Advice From The Pharmacist
- Take Nourianz exactly as prescribed, and do not stop taking it abruptly without consulting your healthcare provider, as this may lead to withdrawal symptoms.
- Monitor for any side effects, including hallucinations, confusion, or unusual behavior, and report these to your healthcare provider.
- Maintain adequate hydration, as amantadine can cause dry mouth.
Side Effects of Nourianz
Common Side Effects
- Nausea
- Dizziness
- Insomnia
- Dry mouth
- Constipation
Uncommon/Severe Side Effects
- Hallucinations or confusion
- Severe allergic reactions (rash, itching, swelling
Risks and Warnings of Nourianz
- Cognitive Effects: Monitor for changes in mood or behavior, especially in elderly patients, as they may be more susceptible to side effects.
- Renal Impairment: Use caution in patients with kidney issues, and adjust dosing as necessary.
Interactions with Nourianz
Common Drug Interactions
- Other Medications: Inform your healthcare provider about all medications you are taking, especially those affecting renal function or CNS activity.
Alternatives to Nourianz
- Other Antiparkinsonian Agents: Such as levodopa/carbidopa or dopamine agonists for similar indications.
- Other Antivirals: For influenza treatment, other options may include oseltamivir or zanamivir.
