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Neomycin-Polymyxin-Dexameth
Neomycin-Polymyxin-Dexameth is a combination topical medication used to treat bacterial infections and reduce inflammation. It contains neomycin and polymyxin B, which are antibiotics, along with dexamethasone, a corticosteroid that helps to relieve inflammation and itching.
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Frequently Asked Questions
How quickly does Neomycin-Polymyxin-Dexameth work?
Most patients begin to notice improvement in their symptoms within 2 to 3 days of starting treatment.
Can I use Neomycin-Polymyxin-Dexameth with other topical medications?
Yes, but consult your healthcare provider before combining with other topical treatments to avoid irritation.
What should I do if I miss a dose?
If you miss a dose, apply it as soon as you remember. If it's close to the time for your next dose, skip the missed dose and continue with your regular schedule.
Are there any dietary restrictions while using Neomycin-Polymyxin-Dexameth?
There are no specific dietary restrictions while using Neomycin-Polymyxin-Dexameth.
Is Neomycin-Polymyxin-Dexameth safe during pregnancy or breastfeeding?
Consult your healthcare provider if you are pregnant or breastfeeding to discuss the risks and benefits of using Neomycin-Polymyxin-Dexameth during these periods.
Comprehensive Drug Guide
How Does Neomycin-Polymyxin-Dexameth Work?
- Neomycin: An aminoglycoside antibiotic that inhibits bacterial protein synthesis, effectively killing a broad spectrum of bacteria.
- Polymyxin B: A peptide antibiotic that disrupts the bacterial cell membrane, enhancing its antibacterial effects.
- Dexamethasone: A corticosteroid that reduces inflammation, redness, and itching associated with infections.
Common Dosages
- Ointment or Cream: Commonly available in a formulation that includes 0.5% neomycin, 10,000 units/mL polymyxin B, and 0.1% dexamethasone.
Typical Dosing
- For skin infections: Apply a thin layer of Neomycin-Polymyxin-Dexameth to the affected area 2 to 3 times daily, or as directed by a healthcare provider.
Typical Dosing
FDA Approved Indications
- Bacterial Infections: for the treatment of superficial skin infections caused by susceptible bacteria.
- Inflammatory Conditions: where a bacterial infection is present along with inflammation.
Who Shouldn't Take Neomycin-Polymyxin-Dexameth?
- Known hypersensitivity to neomycin, polymyxin B, dexamethasone, or any component of the formulation.
- Viral or fungal infections of the skin.
Advice From The Pharmacist
- Apply the medication as directed, and wash your hands before and after use.
- Avoid contact with the eyes, as it may cause irritation.
- If symptoms do not improve within a few days, or if they worsen, consult your healthcare provider.
Side Effects of Neomycin-Polymyxin-Dexameth
Common Side Effects
- Local irritation or redness at the application site
- Itching or burning sensation
- Dryness of the skin
Uncommon/Severe Side Effects
- Severe allergic reactions (rash, itching, swelling)
- Signs of superinfection (new infection developing).
Risks and Warnings of Neomycin-Polymyxin-Dexameth
- Superinfection: Prolonged use of antibiotics can lead to the overgrowth of non-susceptible organisms, including fungi.
- Corticosteroid Risks: Prolonged use of topical corticosteroids can lead to skin thinning and systemic absorption, especially in large areas or under occlusive dressings.
Interactions with Neomycin-Polymyxin-Dexameth
Common Drug Interactions
- Other Topical Agents: Use with caution when combining with other topical treatments, as they may increase irritation.
- Systemic Corticosteroids: Caution is advised when used with systemic corticosteroids due to potential additive effects.
Alternatives to Neomycin-Polymyxin-Dexameth
- Other Topical Antibiotics: Such as mupirocin or bacitracin for skin infections.
- Non-Antibiotic Topical Treatments: Depending on the nature of the skin condition.
