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Bacitracin

Bacitracin is an antibiotic commonly used in topical form to prevent and treat minor skin infections caused by cuts, scrapes, and burns. It works by inhibiting bacterial cell wall synthesis, which prevents the growth and multiplication of bacteria. Bacitracin is effective against a wide range of Gram-positive bacteria, making it a useful option for preventing infections in minor wounds. It is available over-the-counter in ointment form and is often included in combination products with other antibiotics like neomycin and polymyxin B.


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Frequently Asked Questions

How long should I use Bacitracin on a wound?
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Bacitracin should be used until the wound has healed or as directed by a healthcare provider. If there is no improvement in the wound after 7 days or if the condition worsens, it is advisable to consult a healthcare provider.

Can I use Bacitracin for a burn?
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Bacitracin can be used on minor burns to prevent infection, but it should not be used on large, severe burns without medical supervision. For serious burns, seek medical attention promptly.

Is Bacitracin safe to use during pregnancy?
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Bacitracin is generally considered safe for use during pregnancy when used topically and as directed. However, pregnant women should consult their healthcare provider before using any medication to ensure it is appropriate for their specific situation.

What should I do if I have an allergic reaction to Bacitracin?
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If you experience an allergic reaction, such as rash, itching, swelling, or difficulty breathing, discontinue use of Bacitracin immediately and seek medical attention.

Can Bacitracin be used on children?
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Yes, Bacitracin can be used on children for the treatment of minor cuts, scrapes, and burns. However, it should be used under adult supervision, and the affected area should be kept clean to avoid infection.

Can I use Bacitracin if I am allergic to penicillin?
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Yes, Bacitracin is not a penicillin-type antibiotic, so an allergy to penicillin does not mean you will be allergic to Bacitracin. But as with any medication, it's possible to be allergic to Bacitracin itself.

Comprehensive Drug Guide

How Does Bacitracin Work?

Bacitracin works by interfering with the synthesis of bacterial cell walls. It inhibits the enzyme that bacteria use to form their cell walls, which is essential for their survival. Without a functional cell wall, bacteria cannot maintain their structural integrity, leading to cell death. Bacitracin is particularly effective against Gram-positive bacteria, including strains of Staphylococcus and Streptococcus species, which are common causes of skin infections.



What is Bacitracin Used For?

Bacitracin is FDA-approved for the prevention of infection in minor cuts, scrapes, and burns. It is applied topically to the affected area to prevent bacterial growth and promote healing. Bacitracin may also be used in certain surgical settings, such as during eye surgery, to prevent infections. Off-label uses may include the treatment of superficial skin infections, though these should be determined by a healthcare provider.


Common Dosages

Bacitracin is available as an over-the-counter (OTC) ointment, typically in small tubes for easy application to minor cuts, scrapes, and burns. It is not classified as a controlled substance and can be purchased without a prescription. Bacitracin may also be found in combination with other antibiotics in products such as triple antibiotic ointments, which are also available OTC.


Ointment: 400 units/g, 500 units/g


Typical Dosing

FDA Approved Indications

The typical dosing for Bacitracin involves applying a small amount of the ointment to the affected area 1 to 3 times per day. It should be applied to clean, dry skin, and the area can be covered with a sterile bandage if desired. Treatment duration usually lasts until the wound is healed or as directed by a healthcare provider.

Pediatric Dosing

Bacitracin's pediatric dosing is similar to adult dosing. Apply a small amount of the antibiotic to the wound 1 to 3 times daily, covering the area with a clean bandage after each application.

Who Shouldn't Take Bacitracin?

  • Individuals who have an allergy to bacitracin or any other ingredient found in the product.
  • If you've had previous severe or anaphylactic reactions to antibiotics.



Advice From The Pharmacist

  • Only use Bacitracin on the skin. Avoid getting it in your eyes or mouth.
  • If the medication is ingested by accident, seek immediate medical help.
  • If you have any allergic reaction to the medication, like a rash, stop using it and contact your healthcare provider.
  • Always follow the instructions on the product package unless told otherwise by your doctor.

Side Effects of Bacitracin

Common Side Effects

Common side effects of Bacitracin are generally mild and may include local irritation, redness, or itching at the application site. In rare cases, patients may experience an allergic reaction, characterized by rash, itching, swelling, dizziness, or difficulty breathing. Severe allergic reactions are uncommon but require immediate medical attention. Prolonged use of Bacitracin can potentially lead to an overgrowth of non-susceptible organisms, including fungi.



Risks and Warnings of Bacitracin

  • If you experience allergic reactions, like rashes, or more severe symptoms like trouble breathing or swallowing, stop using the ointment and seek immediate medical attention.
  • Avoid contact with eyes or the inside of the mouth or nose. If the ointment does somehow get in these areas, rinse with plenty of water.
  • Bacitracin should not be used for deep wounds, severe burns, or animal bites unless directed by a healthcare provider.



Interactions with Bacitracin

Common Drug Interactions

Bacitracin is used topically and has minimal systemic absorption, so drug interactions are unlikely. However, patients should inform their healthcare provider about all medications and topical treatments they are using to ensure there are no contraindications or potential interactions. It is important to avoid using Bacitracin with other topical medications in the same area unless directed by a healthcare provider.



Alternatives to Bacitracin

  • Neosporin (a combination of bacitracin, neomycin, and polymyxin B)
  • Polysporin (a combination of bacitracin and polymyxin B)
  • Triple antibiotic ointment (includes neomycin)
  • Mupirocin
  • Retapamulin