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Mupirocin Calcium
Mupirocin calcium is a topical antibiotic used to treat bacterial skin infections, particularly those caused by Staphylococcus aureus and Streptococcus pyogenes. It is commonly prescribed for conditions such as impetigo and infected skin lesions. Mupirocin works by inhibiting bacterial protein synthesis, thereby stopping the growth of the bacteria.
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Frequently Asked Questions
How quickly does mupirocin calcium work?
Many patients notice improvement in their condition within 3 to 5 days of starting treatment, but it is important to complete the full course.
Can I use mupirocin calcium with other skin products?
Yes, but it’s best to apply mupirocin first and allow it to dry before applying other topical products.
What should I do if I miss a dose?
If you miss a dose, apply it as soon as you remember. If it’s close to the time for your next application, skip the missed dose and continue with your regular schedule.
Are there any dietary restrictions while using mupirocin calcium?
There are no specific dietary restrictions while using mupirocin.
Is mupirocin calcium safe during pregnancy or breastfeeding?
Consult your healthcare provider if you are pregnant or breastfeeding to discuss the risks and benefits of using mupirocin calcium.
Comprehensive Drug Guide
How Does Mupirocin Calcium Work?
Mupirocin works by binding to bacterial isoleucyl-tRNA synthetase, an enzyme critical for protein synthesis. This inhibition prevents the incorporation of isoleucine into bacterial proteins, leading to a halt in bacterial growth and reproduction.
Common Dosages
- Topical Ointment: 2% formulation.
- Topical Cream: 2% formulation.
Typical Dosing
- Apply a small amount of mupirocin to the affected area three times a day for up to 10 days, or as directed by a healthcare provider.
Typical Dosing
FDA Approved Indications
- Impetigo: for the treatment of superficial skin infections.
- Secondary Infections: for the treatment of infected skin lesions.
Off-Label Uses
Who Shouldn't Take Mupirocin Calcium?
- Known hypersensitivity to mupirocin or any component of the formulation.
- Open wounds or on mucous membranes unless directed by a healthcare provider.
Advice From The Pharmacist
- Apply mupirocin only to the affected area, and wash hands before and after application to prevent the spread of infection.
- Avoid covering the treated area with a bandage unless directed by a healthcare provider.
- Continue treatment for the full prescribed duration, even if symptoms improve, to ensure the infection is fully cleared.
Side Effects of Mupirocin Calcium
Common Side Effects
- Burning or stinging sensation at the application site
- Itching or rash
- Dryness of the skin
Uncommon/Severe Side Effects
- Severe allergic reactions (rash, itching, swelling)
- Signs of a secondary infection.
Risks and Warnings of Mupirocin Calcium
- Local Irritation: Monitor for signs of local irritation or allergic reactions; discontinue use if severe reactions occur.
- Not for Systemic Use: Mupirocin is for topical use only and should not be used in the eyes or ingested.
Interactions with Mupirocin Calcium
Common Drug Interactions
- Other Topical Agents: Use caution when applying mupirocin with other topical medications to avoid irritation.
Alternatives to Mupirocin Calcium
- Other Topical Antibiotics: Such as bacitracin or neomycin for similar skin infections.
- Oral Antibiotics: May be considered for more extensive or systemic infections.
