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Morphine Sulfate ER
Morphine Sulfate ER is an opioid medication utilized for the management of severe and chronic pain. Thanks to its potent narcotic properties, it offers powerful relief for those undergoing surgeries, facing cancerrelated pain, or suffering from certain cardiac conditions. Mild, shortterm side effects might include drowsiness, constipation, nausea, and sweating. However, prolonged use can lead to opioid addiction or dependence.
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Frequently Asked Questions
Can I have a glass of wine while on Morphine Sulfate ER?
Alcohol can interfere with Morphine Sulfate ER's action and may lead to severe side effects such as respiratory depression. It's best to avoid alcohol entirely while on this medication.
Can I just stop taking Morphine Sulfate ER if the pain is gone?
Morphine Sulfate ER can cause dependency and stopping suddenly can lead to withdrawal. Always follow your doctor ??s instructions concerning dosage reduction or cessation.
Can I take Morphine Sulfate ER if I have liver disease?
Morphine Sulfate ER is metabolized and eliminated by the liver, so any liver impairment can affect how the drug works in your body. It's best to discuss any liver conditions with your healthcare provider before administration.
Does Morphine Sulfate ER make you sleepy?
Yes, Morphine Sulfate ER can cause drowsiness or dizziness. Always err on the side of caution and avoid tasks requiring alertness, such as driving, until you're certain it won ??t affect your abilities.
I missed a dose of Morphine Sulfate ER, what should I do?
If it's almost time for your next dose, skip the missed dose. Otherwise, take it as soon as you remember. Never take a double dose to make up for the missed one.
Will Morphine Sulfate ER affect my mood?
Morphine Sulfate ER can alter mood and mental responses, inducing a euphoric state in some patients. If mood changes become an issue, contact your healthcare provider immediately.
Comprehensive Drug Guide
How Does Morphine Sulfate ER Work?
Morphine Sulfate ER is a potent narcotic pain medication that works by binding to the body's opioid receptors primarily located in the brain and spinal cord, effectively blocking the perception of pain stimuli.
What is Morphine Sulfate ER Used For?
FDA indications: Morphine Sulfate ER is typically used for the management of severe acute, chronic, and cancerrelated pain.
Offlabel uses: It's also utilized to relieve shortness of breath at rest (dyspnea) associated with serious medical conditions.
Common Dosages
Tablets: 15mg, 30mg, 60mg, 100mg, and 200mg
Oral solution: 10mg per 5mL or 20mg per mL
Injectable solution: 0.5mg/mL, 1mg/mL, 2mg/mL, 4mg/mL, 5mg/mL, 8mg/mL, and 10mg/mL
Typical Dosing
FDA Approved Indications
- or FDAapproved indications:
- Postsurgical and traumarelated severe pain: Initial dose varies but commonly starts from 1530mg every 4 hours.
- Chronic severe pain: Dosage tailored to the individual patient's need, monitoring closely for side effects.
Off-Label Uses
- For offlabel uses:
- Dyspnea in terminally ill patients: Variable & depends on the healthcare provider's judgment.
Who Shouldn't Take Morphine Sulfate ER?
- Those who are overly sensitive to Morphine Sulfate ER or any other opioids.
- Patients with known or suspected gastrointestinal obstruction.
- Individuals with significant respiratory depression unmonitored by resuscitative equipment.
- Patients with acute or severe bronchial asthma.
- Those with a known history of substance abuse or addiction.
- Pregnant women, unless the benefits outweigh the potential risks.
- Patients with untreated Addison's disease, hypothyroidism, and epilepsy.
Advice From The Pharmacist
- Morphine Sulfate ER should be taken exactly as directed to avoid potential overdose or withdrawal.
- Consuming alcohol or other CNS depressants while on Morphine Sulfate ER may enhance its sedative effects.
- Morphine Sulfate ER may impair judgment or coordination, so avoid operating machinery until you're sure it won't affect your abilities.
- Abrupt cessation after longterm use can trigger withdrawal symptoms. If treatment needs to be halted, doses should be reduced slowly, and under medical supervision.
Side Effects of Morphine Sulfate ER
Common Side Effects
- You might experience constipation or nausea.
- You might feel drowsy or dizzy.
- You might have a headache.
Uncommon/Severe Side Effects
- Rare side effects:
- You might have blurry vision or feel weak.
- Severe side effects:
- If you experience shallow breathing, slow heartbeat, or seizures get medical help immediately.
- Signs of a severe allergic reaction such as rash, itching, severe dizziness, or trouble breathing need immediate medical attention.
Risks and Warnings of Morphine Sulfate ER
- Alert: Regular use can trigger addiction and overdose. Morphine Sulfate ER has a high potential for misuse and should be used only as directed.
- Alert: It's vital to seek immediate medical attention in case of an overdose, as it can result in potentially fatal respiratory depression.
Interactions with Morphine Sulfate ER
Common Drug Interactions
- Other opioid analgesics
- Benzodiazepines
- Antihistamines
- Alcohol
- Antidepressants (like fluoxetine, sertraline)
Alternatives to Morphine Sulfate ER
- Fentanyl
- Hydrocodone
- Oxycodone
- Hydromorphone
- Codeine
- Tramadol
