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fentaNYL
FentaNYL is a potent opioid analgesic used to manage severe pain, particularly in patients who are opioid-tolerant and require continuous pain relief. It is often used for chronic pain that cannot be controlled by other pain medications. FentaNYL is available in various forms, including transdermal patches, injections, and lozenges. It works by binding to opioid receptors in the brain and spinal cord to reduce the sensation of pain.
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Frequently Asked Questions
How should I dispose of FentaNYL patches?
Fold the patch in half, sticky sides together, and dispose of it according to local regulations. Some pharmacies may have take-back programs for opioids.
Can I cut FentaNYL patches to adjust the dose?
No, cutting FentaNYL patches can release a dangerous amount of medication all at once and should never be done.
How long does FentaNYL stay in your system?
The effects of a FentaNYL patch last for 72 hours, but traces of the drug can remain in the body for several days after the patch is removed.
Is FentaNYL stronger than morphine?
Yes, FentaNYL is significantly stronger than morphine, with roughly 50 to 100 times the potency.
Can FentaNYL be used for short-term pain relief?
FentaNYL is typically reserved for long-term, chronic pain management in opioid-tolerant patients and is not recommended for short-term pain relief due to its potency and risk of overdose.
Comprehensive Drug Guide
How Does fentaNYL Work?
FentaNYL works by binding to mu-opioid receptors in the central nervous system, altering the perception of pain and emotional response to pain. It produces strong analgesic effects, as well as sedation, and can depress respiratory function in high doses.
Common Dosages
- Transdermal patches: 12 mcg/hr, 25 mcg/hr, 50 mcg/hr, 75 mcg/hr, 100 mcg/hr
- Injections: various strengths for hospital use
Typical Dosing
- Transdermal patches: Apply a new patch every 72 hours. The dose is individualized based on the patient's level of pain and opioid tolerance.
- Injections: Dosing depends on the severity of pain and is typically administered in a hospital setting.
Typical Dosing
FDA Approved Indications
- Management of chronic pain in opioid-tolerant patients
- Postoperative pain (injection form)
- Breakthrough cancer pain (lozenges, nasal spray)
Who Shouldn't Take fentaNYL?
- Severe respiratory depression
- Acute or severe asthma
- Known hypersensitivity to fentaNYL
Advice From The Pharmacist
- Apply FentaNYL patches to clean, dry skin on the upper body. Avoid applying heat (e.g., heating pads) to the patch area, as it can increase the release of the drug and lead to overdose.
- Do not stop FentaNYL suddenly; tapering is required to prevent withdrawal symptoms.
- Store FentaNYL securely to prevent misuse by others, especially children.
Side Effects of fentaNYL
Common Side Effects
- Drowsiness
- Constipation
- Nausea
- Dry mouth
Uncommon/Severe Side Effects
- Respiratory depression
- Overdose
- Severe allergic reactions
Risks and Warnings of fentaNYL
- Respiratory Depression: FentaNYL can cause life-threatening respiratory depression, especially when used at high doses or combined with other CNS depressants.
- Addiction and Abuse: As a Schedule II controlled substance, FentaNYL has a high potential for addiction, abuse, and misuse.
Interactions with fentaNYL
Common Drug Interactions
- Benzodiazepines: Concurrent use increases the risk of respiratory depression.
- Alcohol: Should be avoided while using FentaNYL, as it can enhance CNS depression and increase the risk of overdose.
Alternatives to fentaNYL
- OxyContin (oxycodone)
- Morphine sulfate
- Hydromorphone (Dilaudid)
