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Lidorex

Lidorex is a topical anesthetic containing lidocaine hydrochloride, used to provide temporary relief of pain and discomfort from conditions such as minor burns, sunburn, insect bites, scrapes, and minor skin irritations. Lidorex works by numbing the skin and surrounding tissues, reducing the sensation of pain. It is commonly used before minor medical procedures or to manage acute pain from superficial skin injuries.

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Frequently Asked Questions

How quickly does Lidorex start working?
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Lidorex typically begins to work within minutes of application, providing temporary pain relief.

How long does the numbing effect of Lidorex last?
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The numbing effect of Lidorex usually lasts 30 minutes to 2 hours, depending on the concentration used and the area of application.

Can I use Lidorex on open wounds?
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No, Lidorex should not be applied to open wounds or broken skin, as this can increase the risk of systemic absorption and side effects.

What should I do if I accidentally ingest Lidorex?
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If Lidorex is ingested, seek immediate medical attention, as systemic absorption of lidocaine can cause serious health issues such as seizures or cardiac arrhythmias.

Can Lidorex be used for children?
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Lidorex can be used in children, but careful dosing and supervision are essential to avoid over-application, which could lead to systemic side effects. Always consult with a healthcare provider before using it on children.

Comprehensive Drug Guide

How Does Lidorex Work?

Lidorex works by blocking sodium channels in nerve cells, which inhibits the transmission of pain signals to the brain. By preventing these pain signals from being transmitted, Lidorex provides a localized numbing effect, reducing the sensation of pain in the area where it is applied.

Common Dosages

  • 2% to 4% topical solution.

The typical dosing depends on the area being treated and the severity of the pain.

Typical Dosing

  • For minor skin irritations: Apply a thin layer of the solution to the affected area up to 3 to 4 times daily as needed for pain relief.
  • For pre-procedural anesthesia: The dosage and duration of application will depend on the specific procedure. Typically, a small amount of Lidorex is applied to the skin or mucous membranes and allowed to sit for a few minutes before the procedure begins.

Typical Dosing

FDA Approved Indications

  • Temporary relief of pain from minor skin irritations, including burns, sunburn, insect bites, and scrapes.
  • Topical anesthesia before minor medical or dental procedures, such as injections or minor surgeries.

Who Shouldn't Take Lidorex?

  • Known hypersensitivity or allergy to lidocaine or any other components of the formulation.
  • Severe liver disease, as lidocaine is metabolized in the liver and may accumulate in such patients.
  • Broken or infected skin in the area where the medication will be applied.

Advice From The Pharmacist

  • Apply a thin layer of Lidorex to the affected area and avoid using it on large areas of skin or for prolonged periods unless directed by your doctor.
  • Do not apply to broken skin or open wounds, as this may increase the risk of systemic absorption and side effects.
  • Wash your hands before and after applying Lidorex, unless treating your hands, to avoid spreading the medication to other areas.
  • Avoid getting Lidorex in the eyes, nose, or mouth, and if this happens, rinse thoroughly with water.
  • Do not use more than the recommended dose, as excessive use can increase the risk of serious side effects, including systemic toxicity.

Side Effects of Lidorex

Common Side Effects

  • Mild skin irritation at the application site
  • Redness
  • Temporary numbness or tingling in the treated area

Uncommon/Severe Side Effects

  • Allergic reactions (e.g., rash, itching, swelling, difficulty breathing)
  • Systemic toxicity, which can cause symptoms such as dizziness, confusion, blurred vision, or an irregular heartbeat, especially if used over large areas or for prolonged periods.

Risks and Warnings of Lidorex

  • Systemic Absorption: Applying Lidorex to large areas of skin, broken skin, or using excessive amounts can lead to systemic absorption of lidocaine, which may cause serious side effects such as seizures, cardiac arrhythmias, or respiratory depression.
  • Allergic Reactions: Patients with a history of allergic reactions to local anesthetics or amide-type anesthetics should avoid using Lidorex and seek medical advice for alternatives.
  • Liver Disease: Lidocaine is metabolized by the liver, so patients with severe liver impairment should use Lidorex cautiously and under medical supervision.

Interactions with Lidorex

Common Drug Interactions

  • Class I antiarrhythmics (e.g., mexiletine, quinidine): These drugs may increase the risk of toxic effects when used with lidocaine.
  • Other local anesthetics: Using multiple local anesthetics can increase the risk of systemic toxicity.

Alternatives to Lidorex

  • Benzocaine topical: Another topical anesthetic used for numbing the skin, available over the counter.
  • Tetracaine: A more potent local anesthetic for short-term numbing of the skin or mucous membranes.
  • Topical hydrocortisone: For minor skin irritation with an inflammatory component, hydrocortisone can provide relief.