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Lidocaine (Anorectal)

Lidocaine (anorectal) is a local anesthetic commonly used to relieve pain and discomfort in the anal and rectal area, particularly during conditions such as hemorrhoids, anal fissures, or other anorectal disorders. By blocking nerve signals in the targeted area, lidocaine provides temporary relief from pain and itching, making it easier for patients to manage their symptoms.



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Frequently Asked Questions

How quickly does lidocaine work?
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Lidocaine usually provides relief within a few minutes of application, lasting for about 30 minutes to 2 hours, depending on the formulation.

Can I use lidocaine while pregnant or breastfeeding?
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Consult your healthcare provider before using lidocaine if you are pregnant or breastfeeding to ensure it is safe for you.

How often can I apply lidocaine?
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You can apply lidocaine up to four times a day as needed, but do not exceed the recommended dosage.

What should I do if I experience a severe reaction?
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If you notice any severe allergic reactions or signs of systemic toxicity, stop using the product and seek immediate medical attention.

Is lidocaine safe for long-term use?
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Lidocaine is generally safe for short-term use, but prolonged use should be discussed with a healthcare provider to avoid potential side effects.

Comprehensive Drug Guide

How Does Lidocaine (Anorectal) Work?

Lidocaine works by blocking sodium channels in the nerve endings located in the affected area. This action prevents the generation and transmission of nerve impulses, effectively numbing the area and providing relief from pain and discomfort.



Common Dosages

  • Topical creams or ointments: 2% or 5% lidocaine
  • Suppositories: 4% lidocaine

Typical Dosing

  • For external use: Apply a small amount of lidocaine cream or ointment to the affected area up to 4 times a day as needed.
  • For suppositories: Insert one suppository into the rectum up to 3 times a day as directed by a healthcare provider.


Typical Dosing

FDA Approved Indications

  • Pain and discomfort associated with hemorrhoids
  • Anal fissures
  • Other conditions affecting the anorectal region


Who Shouldn't Take Lidocaine (Anorectal)?

  • Known hypersensitivity to lidocaine or any other local anesthetic
  • Severe liver disease
  • Heart rhythm disorders


Advice From The Pharmacist

  • Ensure to apply lidocaine only to the affected area and wash hands thoroughly after application.
  • Avoid using other topical products on the same area unless advised by a healthcare provider.
  • If symptoms persist beyond a few days or worsen, contact your healthcare provider for further evaluation.
  • Do not exceed the recommended dosage to avoid potential side effects.


Side Effects of Lidocaine (Anorectal)

Common Side Effects

  • Localized irritation or redness
  • Burning or stinging sensation upon application


Uncommon/Severe Side Effects

  • Allergic reactions (rash, itching, swelling)
  • Symptoms of systemic toxicity, such as dizziness, confusion, or seizures, especially if used excessively.


Risks and Warnings of Lidocaine (Anorectal)

  • Local Reactions: Be aware of any signs of severe irritation or allergic reactions. If these occur, discontinue use and seek medical advice.
  • Absorption: Lidocaine can be absorbed systemically, especially with excessive use. Monitor for signs of systemic toxicity.
  • Underlying Conditions: Patients with pre-existing heart or liver conditions should use lidocaine cautiously and under medical supervision.


Interactions with Lidocaine (Anorectal)

Common Drug Interactions

  • Other Anesthetics: Caution should be used when combining lidocaine with other local anesthetics to avoid additive effects.
  • Medications Affecting Heart Rhythm: Patients taking medications that affect heart rhythm should consult their healthcare provider before using lidocaine.


Alternatives to Lidocaine (Anorectal)

  • Hydrocortisone: A topical corticosteroid that can help reduce inflammation and itching associated with hemorrhoids.
  • Witch Hazel: An over-the-counter topical treatment that provides soothing relief from itching and irritation.
  • Topical analgesics: Other formulations containing different local anesthetics, such as benzocaine.