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Katarvia

Katarvia is a prescription medication that combines brimonidine and timolol, primarily used to treat ocular hypertension and open-angle glaucoma. This combination works synergistically to lower intraocular pressure by reducing the production of aqueous humor and increasing its outflow.

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Frequently Asked Questions

How long does it take for Katarvia to start working?
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Katarvia typically begins to lower intraocular pressure within 1 to 2 hours of administration, with maximum effects usually observed within 2 to 4 hours.

Can I take Katarvia with other medications?
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Always consult your healthcare provider before combining Katarvia with other medications, especially other ocular treatments.

What should I do if I miss a dose of Katarvia?
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If you miss a dose, take it as soon as you remember. If it’s close to the time for your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Is it safe to use Katarvia during pregnancy?
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Katarvia should be used during pregnancy only if clearly needed, and the risks and benefits should be discussed with a healthcare provider.

Can Katarvia cause weight gain?
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Weight gain is not a common side effect of Katarvia. Any significant changes in weight should be discussed with a healthcare provider.

Comprehensive Drug Guide

How Does Katarvia Work?

  • Brimonidine: Works by stimulating alpha-2 adrenergic receptors, which decreases aqueous humor production and increases its outflow.
  • Timolol: Reduces aqueous humor production by blocking beta-adrenergic receptors in the ciliary body.


Common Dosages

  • Ophthalmic solution: Usually contains brimonidine 0.2% and timolol 0.5%.

Typical Dosing

  • The usual dosage is 1 drop in the affected eye(s) twice daily, approximately 12 hours apart.


Typical Dosing

FDA Approved Indications

  • Lowering intraocular pressure in patients with open-angle glaucoma or ocular hypertension.


Who Shouldn't Take Katarvia?

  • Known hypersensitivity to brimonidine, timolol, or any components of the formulation
  • Asthma, chronic obstructive pulmonary disease (COPD), or other respiratory conditions
  • Certain heart conditions, such as bradycardia or heart block


Advice From The Pharmacist

  • Patients should be instructed on the proper technique for administering eye drops to avoid contamination and ensure effectiveness.
  • Advise patients to avoid touching the dropper tip to any surface, including the eye.
  • Inform patients about potential side effects, including fatigue, dizziness, or changes in heart rate.


Side Effects of Katarvia

Common Side Effects

  • Eye irritation or redness
  • Dry mouth
  • Fatigue
  • Dizziness
  • Headache


Uncommon/Severe Side Effects

  • Severe allergic reactions (anaphylaxis)
  • Respiratory issues in patients with underlying conditions
  • Bradycardia or other heart-related issues


Risks and Warnings of Katarvia

  • Cardiovascular Risks: Monitor patients with a history of heart disease or respiratory issues, as timolol can exacerbate these conditions.
  • Ocular Effects: Caution should be exercised in patients with pre-existing eye conditions.


Interactions with Katarvia

Common Drug Interactions

  • Other Ocular Agents: Use caution when administering with other eye medications to avoid interactions that may affect intraocular pressure.
  • CNS Depressants: Caution is advised when used with medications that may cause sedation or respiratory depression.


Alternatives to Katarvia

  • Other Combination Products: Such as dorzolamide and timolol for lowering intraocular pressure.
  • Prostaglandin Analogues: Like latanoprost for similar indications.