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Invokamet
Invokamet is a prescription medication that belongs to the drug class of combination oral antihyperglycemic agents. This medication is primarily used to manage type 2 diabetes and works by aiding the kidneys in removing glucose from the bloodstream. Potential side effects can include upset stomach, nausea, diarrhea, vomiting, and dizziness.
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Frequently Asked Questions
Can I take Invokamet if I'm allergic to sulfonylureas?
Since Invokamet has a different drug class, it is typically safe for individuals with sulfonylureas hypersensitivity. However, because individual reactions can differ, it's essential to discuss any known allergies with your healthcare provider.
Can Invokamet be used by pregnant or breastfeeding women?
Invokamet is not generally recommended for use during pregnancy or while breastfeeding, as it could potentially harm the baby. Consult your healthcare provider to discuss potential risks and benefits.
Does Invokamet have any interactions with foods or other medications?
Yes, Invokamet can interact with other medications, potentially impacting its effectiveness. Additionally, consuming alcohol may increase the risk of a rare but serious metabolic complication called lactic acidosis. For a comprehensive understanding of possible interactions, always consult your healthcare professional.
What should I do if I miss a dose of Invokamet?
If you miss a dose of Invokamet, take it as soon as you remember, unless it's nearly time for your next dose. Do not double your dose to make up for a missed one. If it's almost time for your next dose, skip the missed dose and continue on your regular schedule. As always, if you're unsure, consult your healthcare provider.
Can Canagliflozin help me lose weight?
Yes, Canagliflozin can lead to slight weight loss in some people by helping the body get rid of glucose in urine.
Comprehensive Drug Guide
How Does Invokamet Work?
Canagliflozin is a selective inhibitor of sodium-glucose co-transporter 2 (SGLT2), a transporter that's responsible for 90% of the reabsorption of glucose from the kidneys. By inhibiting this transporter, canagliflozin increases urinary glucose excretion, leading to a lowering of blood glucose levels.
What is Invokamet Used For?
Canagliflozin is indicated for the treatment of type 2 diabetes in adults when diet and exercise do not provide adequate glycemic control.
Common Dosages
- Tablets:100mg, 300mg
Typical Dosing
FDA Approved Indications
- Type 2 Diabetes: Initial dose of 100mg once daily, increased to 300mg daily if necessary.
Off-Label Uses
It can also be used to reduce the risk of cardiovascular death and hospitalization in patients with type 2 diabetes and to lower risks for chronic kidney disease progression in these patients.
- Cardiovascular risk reduction and renal protection: 100mg once daily.
Who Shouldn't Take Invokamet?
- Have severe kidney disease or are on dialysis.
- Have a history of allergic reactions to canagliflozin or any of its ingredients.
- Are in a state of diabetic ketoacidosis.
- Are pregnant or planning to become pregnant, or are breastfeeding.
- Have severe liver disease.
Advice From The Pharmacist
- Make sure to drink plenty of water. Canagliflozin can make you pee more than usual, so dehydration could be a risk.
- Make a point of eating healthily and exercise regularly for better diabetes control.
- Inform your doctor if you experience unusual fatigue, unexplained nausea, vomiting or abdominal pain, or rapid breathing or shortness of breath, as these may be signs of a serious condition called ketoacidosis.
- Don't forget to check your blood glucose levels regularly.
- If you're feeling dizzy or faint, let your doctor know. It might be a side effect of the medication.
- Yeast infections are a common side effect in females. Communication with your doc can help manage them better.
- Lastly, remember that canagliflozin isn't a substitute for a healthy lifestyle but an additional tool to help manage your diabetes.
Side Effects of Invokamet
Common Side Effects
- Urination changes
- Yeast infections
- Weight loss
- Mild dehydration
Uncommon/Severe Side Effects
- Diabetic ketoacidosis
- Serious UTIs
- Kidney problems
- Lower limb amputations
- Fractures
- Hypersensitivity reactions (allergic reactions)
Risks and Warnings of Invokamet
- If you have severe kidney disease or are on dialysis, refrain from using Canagliflozin.
- If you've ever had a severe allergic reaction to Canagliflozin or any of its components, it’s not advisable for you.
- Avoid usage if diagnosed with diabetic ketoacidosis.
- Pregnant or planning to become pregnant or breastfeeding mothers should consult healthcare professionals before use.
- Those with severe liver disease must avoid Canagliflozin.
Interactions with Invokamet
Common Drug Interactions
- Insulin and insulin secretagogues
- Diuretics
- Antihypertensives
- Nonsteroidal anti-inflammatory drugs (NSAIDs)
- Digoxin
Common Food Interactions
- Maintain a balanced diet to help manage diabetes
- Decrease alcohol intake - It can increase your risk of low blood sugar or high blood pressure
Alternatives to Invokamet
- Dapagliflozin (Farxiga)
- Empagliflozin (Jardiance)
- Ertugliflozin (Steglatro)
- Others that could be used but are not SGLT2 inhibitors, but still used in diabetes treatment: Metformin, Glipizide, Glimepiride
