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hydrOXYzine Pamoate
Hydroxyzine Pamoate is an antihistamine that is primarily used to manage anxiety, nausea, and itching caused by allergies. It can also be used as a sedative to help patients relax before surgery or other medical procedures. Hydroxyzine works by blocking histamine receptors in the body, leading to its calming effects.
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Frequently Asked Questions
How long does it take for Hydroxyzine Pamoate to start working?
Patients may begin to feel relief from anxiety or allergic symptoms within 30 minutes to 1 hour after taking the medication.
Can I take Hydroxyzine Pamoate with other medications?
Always consult your healthcare provider before combining Hydroxyzine Pamoate with other medications, especially other sedatives or CNS depressants.
Always consult your healthcare provider before combining Hydroxyzine Pamoate with other medications, especially other sedatives or CNS depressants.
If you miss a dose, take it as soon as you remember. If it’s close to your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
Is it safe to use Hydroxyzine Pamoate during pregnancy?
Hydroxyzine should be used during pregnancy only if clearly needed, and the risks and benefits should be discussed with a healthcare provider.
Can Hydroxyzine Pamoate cause weight gain?
Weight gain is not a common side effect of Hydroxyzine Pamoate; however, any significant changes in weight should be discussed with a healthcare provider.
Comprehensive Drug Guide
How Does hydrOXYzine Pamoate Work?
Hydroxyzine Pamoate works by blocking the effects of histamine, a substance in the body that causes allergic symptoms. It also has anticholinergic properties, which help reduce anxiety and promote sedation by affecting certain neurotransmitters in the brain.
What is hydrOXYzine Pamoate Used For?
FDA indications: Hydroxyzine is used for symptomatic relief of anxiety and tension associated with psychoneurosis and as an adjunct in organic disease states in which anxiety is manifested. It is also useful in the management of pruritus due to allergic conditions such as chronic urticaria and atopic and contact dermatoses and in histamine-mediated pruritus.
Off-label uses: Hydroxyzine has been used off-label for nausea, vomiting, and alcohol withdrawal.
Common Dosages
- Capsules: Common dosages include 25 mg and 50 mg.
Typical Dosing
- For anxiety management, the typical dose for adults is 50-100 mg taken orally, up to four times a day.
- For preoperative sedation, doses of 50-100 mg may be administered before surgery.
- Dosages may vary based on individual patient needs and response to treatment.
Typical Dosing
FDA Approved Indications
- Management of anxiety
- Preoperative sedation
- Relief of itching due to allergic conditions
- Nausea and vomiting
Off-Label Uses
- Off-label uses:
- Nausea and vomiting: 25-100mg every four to six hours
Who Shouldn't Take hydrOXYzine Pamoate?
- Known hypersensitivity to hydroxyzine or any components of the formulation
- Early pregnancy (unless specifically indicated)
- Prolonged QT interval or other significant cardiac conditions
Advice From The Pharmacist
- Patients should be advised to take hydroxyzine with food to reduce the pol for gastrointestinal upset.
- Caution should be exercised when performing activities that require alertness (e.g., driving) until the patient knows how hydroxyzine affects them.
- Patients should be informed about the potential for sedation and should avoid alcohol and other CNS depressants while taking hydroxyzine.
Side Effects of hydrOXYzine Pamoate
Common Side Effects
- Drowsiness
- Dry mouth
- Dizziness
- Fatigue
- Blurred vision
Uncommon/Severe Side Effects
- Severe allergic reactions (anaphylaxis)
- Confusion or agitation, especially in older adults
Risks and Warnings of hydrOXYzine Pamoate
- Sedation Risk: Due to its sedative properties, patients should be cautious when taking hydroxyzine, particularly if they are also taking other medications that cause drowsiness.
- Anticholinergic Effects: Monitor for signs of excessive anticholinergic effects, such as dry mouth, constipation, or urinary retention.
Interactions with hydrOXYzine Pamoate
Common Drug Interactions
- CNS Depressants: Caution is advised when combining hydroxyzine with other sedatives or alcohol, as this can enhance drowsiness.
- MAO Inhibitors: Should not be taken with hydroxyzine due to the potential for severe reactions.
Alternatives to hydrOXYzine Pamoate
- Other Anxiolytics: Such as diazepam or lorazepam, for anxiety management.
- Non-sedating antihistamines: Such as cetirizine or loratadine, for allergic symptoms without sedation.
- Psychotherapy: Such as cognitive behavioral therapy (CBT) for anxiety management.
