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HYDROcodone-Ibuprofen
Hydrocodone-Ibuprofen is a combination medication used to relieve moderate to severe pain. It combines hydrocodone, an opioid analgesic that helps alleviate pain, with ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID) that reduces inflammation and pain. This combination provides enhanced pain relief for conditions such as post-operative pain or injury-related discomfort.
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Frequently Asked Questions
How quickly does Hydrocodone-Ibuprofen work for pain relief?
Patients may start to notice relief within 30 to 60 minutes after taking the medication.
Can I take Hydrocodone-Ibuprofen while pregnant?
Consult your healthcare provider for guidance, as the use during pregnancy should be evaluated based on risks and benefits.
What should I do if I miss a dose?
If you miss a dose, take it as soon as you remember. If it's close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not double up.
Are there any specific storage instructions for Hydrocodone-Ibuprofen?
Store at room temperature, away from moisture and direct sunlight. Keep out of reach of children.
Is Hydrocodone-Ibuprofen safe for long-term use?
Long-term use is generally not recommended due to the potential for dependence on hydrocodone and gastrointestinal complications from ibuprofen. Regular check-ups with a healthcare provider are important for ongoing management.
Comprehensive Drug Guide
How Does HYDROcodone-Ibuprofen Work?
Hydrocodone works by binding to opioid receptors in the brain, reducing the perception of pain. Ibuprofen works by inhibiting the production of prostaglandins, substances in the body that mediate inflammation and pain. The combination of these two mechanisms provides effective pain relief.
Common Dosages
- Tablets: Common strengths include 5 mg of hydrocodone with 200 mg of ibuprofen.
Typical Dosing
The typical dosing for Hydrocodone-Ibuprofen is:
- For Pain Relief: The usual adult dose is 1 tablet taken every 4 to 6 hours as needed for pain, not to exceed 5 tablets in 24 hours.
Typical Dosing
FDA Approved Indications
Management of moderate to severe pain where an opioid analgesic is appropriate.
Who Shouldn't Take HYDROcodone-Ibuprofen?
- Hypersensitivity: Known hypersensitivity to hydrocodone, ibuprofen, or any components of the formulation.
- Severe Respiratory Depression: Should not be used in patients with significant respiratory issues or asthma exacerbations.
- Active Peptic Ulcer Disease: Due to the risk of gastrointestinal bleeding with NSAIDs.
Advice From The Pharmacist
- How to Use: Take the medication as prescribed, with food or milk to minimize gastrointestinal irritation.
- Monitor for Side Effects: Be aware of potential side effects, including drowsiness, gastrointestinal upset, or signs of allergic reactions. Consult a healthcare provider if severe symptoms occur.
- Avoid Alcohol: Alcohol can increase the risk of serious side effects and should be avoided while taking this medication.
Side Effects of HYDROcodone-Ibuprofen
Common Side Effects
- Drowsiness
- Nausea
- Constipation
- Gastrointestinal discomfort
Uncommon/Severe Side Effects
- Respiratory depression: Symptoms like slow or difficult breathing.
- Severe allergic reactions: Such as rash, itching, or difficulty breathing.
- Gastrointestinal bleeding: Signs include black or bloody stools and severe stomach pain.
Risks and Warnings of HYDROcodone-Ibuprofen
- Caution with Other CNS Depressants: Concurrent use with other central nervous system depressants may enhance sedation and respiratory depression.
- Dependence and Withdrawal: Long-term use can lead to physical dependence; tapering off may be necessary when discontinuing.
Interactions with HYDROcodone-Ibuprofen
Common Drug Interactions
- Drug Interactions: Hydrocodone-Ibuprofen may interact with other medications that affect the central nervous system, including sedatives and certain antidepressants. Always inform your healthcare provider about all medications you are taking.
Alternatives to HYDROcodone-Ibuprofen
- Other Opioid Analgesics: Such as oxycodone or morphine for more severe pain.
- NSAIDs: Such as naproxen or acetaminophen for less severe pain management.
