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guanFACINE HCl ER
Guanfacine HCl ER (extended-release) is an alpha-2 adrenergic agonist primarily used in the treatment of attention deficit hyperactivity disorder (ADHD) and for the management of hypertension. It works by affecting receptors in the brain that help regulate attention, impulsivity, and hyperactivity.
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Frequently Asked Questions
How long does it take for Guanfacine HCl ER to work for ADHD?
Some patients may begin to see improvements in symptoms within a week, but optimal effects may take several weeks to establish.
Can I take Guanfacine HCl ER if I am pregnant?
Consult your healthcare provider for guidance, as the safety of guanfacine during pregnancy should be evaluated.
What should I do if I miss a dose?
If you miss a dose, take it as soon as you remember. If it’s close to the next scheduled dose, skip the missed dose and continue with your regular schedule. Do not double up.
Are there any specific storage instructions for Guanfacine HCl ER?
Store at room temperature, away from moisture and direct sunlight. Keep out of reach of children.
Is Guanfacine HCl ER safe for long-term use?
Guanfacine HCl ER can be used long-term, but regular monitoring for side effects and overall effectiveness is important.
Comprehensive Drug Guide
How Does guanFACINE HCl ER Work?
Guanfacine HCl ER works by stimulating alpha-2 adrenergic receptors in the brain, which leads to decreased sympathetic outflow and improved regulation of attention and impulse control. This results in reduced symptoms of ADHD and lowered blood pressure in hypertensive patients.
What is guanFACINE HCl ER Used For?
Guanfacine ER is used to treat ADHD.
Common Dosages
Guanfacine HCl ER is available in the following forms:
- Extended-release tablets: Common strengths include 1 mg, 2 mg, and 3 mg.
Typical Dosing
The typical dosing for Guanfacine HCl ER is:
- For ADHD: The usual starting dose is 1 mg once daily, which may be adjusted based on response and tolerability, up to a maximum of 4 mg daily.
- For Hypertension: The initial dose is often 1 mg to 2 mg once daily, adjusted as needed.
Typical Dosing
FDA Approved Indications
- Treatment of ADHD as part of a comprehensive treatment program.
- Management of hypertension, typically in combination with other antihypertensive agents.
Pediatric Dosing
- Dosage for children depends on the condition being treated and the child's age and weight. Instructions from the doctor should be strictly followed.
- For ADHD, the dose is usually based on weight and age. The starting dose can be 1mg daily and gradually increased if necessary.
- Parents should watch out for noteworthy changes in behavior, sleep patterns, or unusual tiredness.
- The medicine should not be discontinued abruptly, doctors usually recommend a gradual dose reduction.
Who Shouldn't Take guanFACINE HCl ER?
- Hypersensitivity: Known hypersensitivity to guanfacine or any components of the formulation.
- Severe Coronary Artery Disease: Use with caution in patients with severe coronary artery disease.
Advice From The Pharmacist
- How to Take: Take Guanfacine HCl ER once daily, preferably at the same time each day. It can be taken with or without food.
- Avoid Abrupt Discontinuation: Do not stop taking the medication abruptly, as this may lead to rebound hypertension. Gradual tapering is recommended.
- Monitor for Side Effects: Be aware of potential side effects, particularly sedation, dry mouth, and constipation.
Side Effects of guanFACINE HCl ER
Common Side Effects
- Drowsiness
- Dry mouth
- Fatigue
- Constipation
Uncommon/Severe Side Effects
- Bradycardia: Slow heart rate.
- Hypotension: Low blood pressure, particularly with rapid dose adjustments.
Risks and Warnings of guanFACINE HCl ER
- Sedation Risk: Patients should be advised to avoid activities requiring full alertness until they know how the medication affects them.
- Monitoring Required: Regular follow-up appointments are important to monitor blood pressure and overall response to treatment.
Interactions with guanFACINE HCl ER
Common Drug Interactions
- Drug Interactions: Guanfacine HCl ER may interact with other medications that lower blood pressure or central nervous system depressants. Always inform your healthcare provider about all medications you are taking.
- Food Interactions: No significant food interactions are noted.
Alternatives to guanFACINE HCl ER
- Other Stimulants: Such as methylphenidate or amphetamine-based medications.
- Non-stimulant Options: Such as atomoxetine or bupropion.
