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glyBURIDE Micronized
Glyburide Micronized is an oral antihyperglycemic agent used for the management of type 2 diabetes mellitus. It is a micronized formulation of glyburide, which increases its bioavailability and absorption. Glyburide belongs to the class of medications known as sulfonylureas and works by stimulating insulin release from the pancreas, thereby helping to lower blood glucose levels.
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Frequently Asked Questions
How effective is Glyburide Micronized in managing blood sugar?
When taken as prescribed, Glyburide Micronized can be very effective in lowering blood sugar levels in individuals with type 2 diabetes.
Can I take Glyburide Micronized if I am pregnant?
Consult your healthcare provider for guidance if you are pregnant or planning to become pregnant, as the benefits must be weighed against potential risks.
What should I do if I miss a dose?
If you miss a dose, take it as soon as you remember. If it’s close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not double up.
Are there any specific storage instructions for Glyburide Micronized?
Store at room temperature, away from moisture and direct sunlight. Keep out of reach of children.
Is Glyburide Micronized safe for long-term use?
Glyburide Micronized can be used long-term, but regular monitoring of blood glucose levels and potential side effects is important as part of the treatment plan.
Comprehensive Drug Guide
How Does glyBURIDE Micronized Work?
Glyburide Micronized works by binding to specific receptors on pancreatic beta cells, stimulating the secretion of insulin in response to elevated blood glucose levels. It also increases the sensitivity of peripheral tissues to insulin, facilitating the uptake of glucose by cells.
Common Dosages
Glyburide Micronized is available in the following forms:
- Tablets: Common strengths include 1.5 mg, 3 mg, and 6 mg.
Typical Dosing
The typical dosing for Glyburide Micronized is:
- For Type 2 Diabetes: The usual starting dose is 1.5 to 3 mg taken orally once daily, with the dose adjusted based on blood glucose levels and individual response.
Typical Dosing
FDA Approved Indications
Management of type 2 diabetes mellitus as an adjunct to diet and exercise.
Who Shouldn't Take glyBURIDE Micronized?
- Hypersensitivity: Known hypersensitivity to glyburide or any components of the formulation.
- Diabetic Ketoacidosis: Should not be used in patients with diabetic ketoacidosis.
Advice From The Pharmacist
- How to Take: Take Glyburide Micronized with a meal to reduce the risk of hypoglycemia. Consistent timing with meals is important.
- Regular Monitoring: Regularly monitor blood glucose levels and have follow-up appointments to adjust dosing as necessary.
- Diet and Exercise: Emphasize the importance of adhering to a diabetic diet and regular physical activity for optimal management of diabetes.
Side Effects of glyBURIDE Micronized
Common Side Effects
- Hypoglycemia (low blood sugar)
- Nausea
- Diarrhea
- Headache
Uncommon/Severe Side Effects
- Severe hypoglycemia: Symptoms include sweating, confusion, dizziness, and fainting.
- Allergic reactions: Such as rash, itching, or difficulty breathing.
Risks and Warnings of glyBURIDE Micronized
- Hypoglycemia Risk: Patients should be educated on recognizing the signs and symptoms of hypoglycemia and how to manage it.
- Caution in Renal Impairment: Use with caution in patients with kidney dysfunction, as this may affect drug metabolism and excretion.
Interactions with glyBURIDE Micronized
Common Drug Interactions
Glyburide Micronized may interact with other medications that can affect blood sugar levels, including other antidiabetic agents and certain antibiotics. Always inform your healthcare provider about all medications you are taking.
Common Food Interactions
Food Interactions: Take with food to reduce the risk of hypoglycemia.
Alternatives to glyBURIDE Micronized
- Other Sulfonylureas: Such as glipizide or glimepiride.
- Metformin: Often the first-line treatment for type 2 diabetes.
