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Duramorph
Morphine Sulfate is an opioid medication utilized for the management of severe and chronic pain. Thanks to its potent narcotic properties, it offers powerful relief for those undergoing surgeries, facing cancer-related pain, or suffering from certain cardiac conditions. Mild, short-term side effects might include drowsiness, constipation, nausea, and sweating. However, prolonged use can lead to opioid addiction or dependence.
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Frequently Asked Questions
Can I take Morphine Sulfate if I have liver disease?
Morphine Sulfate is metabolized and eliminated by the liver, so any liver impairment can affect how the drug works in your body. It's best to discuss any liver conditions with your healthcare provider before administration.
Does Morphine Sulfate make you sleepy?
Yes, Morphine Sulfate can cause drowsiness or dizziness. Always err on the side of caution and avoid tasks requiring alertness, such as driving, until you're certain it won t affect your abilities.
I missed a dose of Morphine Sulfate, what should I do?
If it's almost time for your next dose, skip the missed dose. Otherwise, take it as soon as you remember. Never take a double dose to make up for the missed one.
Can I just stop taking Morphine Sulfate if the pain is gone?
Morphine Sulfate can cause dependency and stopping suddenly can lead to withdrawal. Always follow your doctor s instructions concerning dosage reduction or cessation.
Will Morphine Sulfate affect my mood?
Morphine Sulfate can alter mood and mental responses, inducing a euphoric state in some patients. If mood changes become an issue, contact your healthcare provider immediately.
Comprehensive Drug Guide
How Does Duramorph Work?
Morphine Sulfate is a potent narcotic pain medication that works by binding to the body's opioid receptors primarily located in the brain and spinal cord, effectively blocking the perception of pain stimuli.
What is Duramorph Used For?
FDA indications: Morphine Sulfate is typically used for the management of severe acute, chronic, and cancer-related pain.
Off-label uses: It's also utilized to relieve shortness of breath at rest (dyspnea) associated with serious medical conditions.
Common Dosages
Tablets: 15mg, 30mg, 60mg, 100mg, and 200mg
Oral solution: 10mg per 5mL or 20mg per mL
Injectable solution: 0.5mg/mL, 1mg/mL, 2mg/mL, 4mg/mL, 5mg/mL, 8mg/mL, and 10mg/mL
Typical Dosing
FDA Approved Indications
- or FDA-approved indications:
- Post-surgical and trauma-related severe pain: Initial dose varies but commonly starts from 15-30mg every 4 hours.
- Chronic severe pain: Dosage tailored to the individual patient's need, monitoring closely for side effects.
Off-Label Uses
- For off-label uses:
- Dyspnea in terminally ill patients: Variable & depends on the healthcare provider's judgment.
Who Shouldn't Take Duramorph?
- Those who are overly sensitive to Morphine Sulfate or any other opioids.
- Patients with known or suspected gastrointestinal obstruction.
- Individuals with significant respiratory depression unmonitored by resuscitative equipment.
- Patients with acute or severe bronchial asthma.
- Those with a known history of substance abuse or addiction.
- Pregnant women, unless the benefits outweigh the potential risks.
- Patients with untreated Addison's disease, hypothyroidism, and epilepsy.
Advice From The Pharmacist
- Morphine Sulfate should be taken exactly as directed to avoid potential overdose or withdrawal.
- Consuming alcohol or other CNS depressants while on Morphine Sulfate may enhance its sedative effects.
- Morphine Sulfate may impair judgment or coordination, so avoid operating machinery until you're sure it won't affect your abilities.
- Abrupt cessation after long-term use can trigger withdrawal symptoms. If treatment needs to be halted, doses should be reduced slowly, and under medical supervision.
Side Effects of Duramorph
Common Side Effects
- You might experience constipation or nausea.
- You might feel drowsy or dizzy.
- You might have a headache.
Uncommon/Severe Side Effects
- Rare side effects:
- You might have blurry vision or feel weak.
- Severe side effects:
- If you experience shallow breathing, slow heartbeat, or seizures - get medical help immediately.
- Signs of a severe allergic reaction such as rash, itching, severe dizziness, or trouble breathing need immediate medical attention.
Risks and Warnings of Duramorph
- Alert: Regular use can trigger addiction and overdose. Morphine Sulfate has a high potential for misuse and should be used only as directed.
- Alert: It's vital to seek immediate medical attention in case of an overdose, as it can result in potentially fatal respiratory depression.
Interactions with Duramorph
Common Drug Interactions
- Other opioid analgesics
- Benzodiazepines
- Antihistamines
- Alcohol
- Antidepressants (like fluoxetine, sertraline)
Alternatives to Duramorph
- Fentanyl
- Hydrocodone
- Oxycodone
- Hydromorphone
- Codeine
- Tramadol
