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Doryx
Doryx MPC (doxycycline hyclate) is a tetracycline antibiotic used to treat a variety of bacterial infections, including acne, respiratory tract infections, urinary tract infections, certain types of skin infections, and sexually transmitted infections (STIs). It works by inhibiting the growth and spread of bacteria. Doryx MPC is an extended-release form of doxycycline, designed to reduce gastrointestinal side effects and provide longer-lasting action.
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Frequently Asked Questions
How long does it take for Doryx MPC to start working?
You may begin to see improvement in your infection or acne within a few days of starting treatment, but it is important to complete the full course as prescribed.
Can I take Doryx MPC with food?
Yes, Doryx MPC can be taken with food to reduce stomach upset, but avoid taking it with dairy products, as calcium can reduce its effectiveness.
What should I do if I miss a dose of Doryx MPC?
If you miss a dose, take it as soon as you remember. If it is close to your next scheduled dose, skip the missed dose and take the next one at your regular time. Do not double up on doses.
Is Doryx MPC safe to take during pregnancy?
No, Doryx MPC is not recommended during pregnancy, particularly in the second and third trimesters, due to the risk of harm to the developing fetus.
Can Doryx MPC treat viral infections, such as the flu?
No, Doryx MPC is an antibiotic and is only effective against bacterial infections. It will not work for viral infections like the flu or the common cold.
Comprehensive Drug Guide
How Does Doryx Work?
Doryx MPC works by inhibiting the synthesis of bacterial proteins, which prevents the bacteria from growing and multiplying. By blocking protein production, Doryx MPC helps the body eliminate the infection. It is effective against a wide range of bacteria, including both gram-positive and gram-negative strains.
Common Dosages
- Delayed-release tablets: 60 mg, 120 mg
Typical Dosing
- For infections: The typical adult dose is 200 mg on the first day (given as 100 mg every 12 hours), followed by 100 mg once daily or 100 mg every 12 hours.
- For acne: The usual dose is 120 mg once daily, with treatment duration depending on the severity of the condition.
- For sexually transmitted infections (e.g., chlamydia): 100 mg twice daily for 7 days.
Typical Dosing
FDA Approved Indications
- Acne vulgaris
- Respiratory tract infections (e.g., pneumonia, bronchitis)
- Urinary tract infections
- Chlamydia and other sexually transmitted infections (STIs)
- Skin and soft tissue infections
Who Shouldn't Take Doryx?
- Known hypersensitivity to doxycycline or other tetracyclines
- Severe liver disease
- Pregnancy (especially during the second and third trimesters)
Advice From The Pharmacist
- Take Doryx MPC with a full glass of water to prevent irritation of the esophagus, and avoid lying down immediately after taking it.
- Avoid taking Doryx MPC with calcium-rich foods, such as dairy products, as they can interfere with absorption.
- Use sun protection while taking Doryx MPC, as it can increase your sensitivity to sunlight and the risk of sunburn.
- If taking Doryx MPC for an infection, complete the full course of the antibiotic, even if you start feeling better, to prevent bacterial resistance.
Side Effects of Doryx
Common Side Effects
- Nausea
- Diarrhea
- Photosensitivity (increased sensitivity to sunlight)
- Stomach pain
Uncommon/Severe Side Effects
- Severe allergic reactions (rash, swelling, difficulty breathing)
- Esophageal irritation or ulcers
- Liver damage
- Severe diarrhea (possibly due to Clostridium difficile infection)
Risks and Warnings of Doryx
- Sun Sensitivity: Doryx MPC can cause increased sensitivity to sunlight, leading to a higher risk of sunburn. Use sunscreen and protective clothing when outdoors.
- Esophageal Irritation: Doryx MPC can cause irritation of the esophagus if not taken properly. Always take it with a full glass of water and remain upright for at least 30 minutes after taking the medication.
- Pregnancy Risk: Doryx MPC should not be used during pregnancy, particularly in the second and third trimesters, as it can harm the developing fetus by affecting bone and tooth development.
Interactions with Doryx
Common Drug Interactions
- Antacids: Calcium, magnesium, and aluminum-containing antacids can reduce the absorption of Doryx MPC.
- Iron supplements: Iron can interfere with the absorption of doxycycline.
- Blood thinners (warfarin): Doryx MPC may increase the effects of blood thinners, increasing the risk of bleeding.
- Oral contraceptives: Doryx MPC may reduce the effectiveness of birth control pills, so an additional form of contraception should be used during treatment.
Alternatives to Doryx
- Minocycline (Minocin): Another tetracycline antibiotic used for similar bacterial infections and acne treatment.
- Clindamycin: An alternative antibiotic often used to treat bacterial skin infections.
- Azithromycin (Zithromax): A macrolide antibiotic commonly used for respiratory infections and sexually transmitted infections.
