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Diuril
Diuril, also known as chlorothiazide, is a medication that belongs to the class of diuretics, often referred to as 'water pills'. It is primarily used to treat high blood pressure and fluid retention caused by various conditions such as heart disease, liver disease, and kidney disease. Some common side effects include thirst, muscle cramps, and nausea. Your healthcare provider will always ensure the benefits of this drug outweigh any potential side effects.
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Frequently Asked Questions
Can I take Diuril if I have diabetes?
Yes, but it needs to be monitored closely by your healthcare provider as it can affect blood sugar levels.
Does Diuril make you urinate more?
Yes, Diuril works by helping your body get rid of extra salt and water through urination.
I missed a dose of Diuril, what should I do?
If it is close to the time for your next dose, skip the missed dose and go back to your normal time. Do not take 2 doses at the same time or extra doses.
Comprehensive Drug Guide
How Does Diuril Work?
Diuril is a thiazide diuretic that increases the excretion of sodium and chloride in approximately equivalent amounts, inhibiting their reabsorption in the cortical diluting segment of the ascending loop of Henle.
What is Diuril Used For?
FDA indications: Diuril is used to treat high blood pressure and to relieve extra fluid in the body (edema) caused by conditions such as heart failure, liver disease, and kidney disease.
Offlabel uses: It may also be used in the treatment of diabetes insipidus and renal tubular acidosis.
Common Dosages
Tablets: 250mg and 500mg
Typical Dosing
FDA Approved Indications
- High blood pressure: The usual dose in adults is 125 to 500mg per day in single or divided doses.
- Edema: The usual dose in adults is 500 to 1000mg or more in single or divided doses.
Off-Label Uses
- Renal tubular acidosis and diabetes insipidus: Dosage varies, depending upon the severity of the condition, and will be determined by the healthcare provider.
Who Shouldn't Take Diuril?
- If you're allergic to sulfa medications, thiazides, or any other part of this drug.
- If you're unable to urinate or have suffered kidney failure.
- If you are pregnant, planning to become pregnant, or are breastfeeding.
- If you have Addison's disease, certain types of kidney disorders, liver disease, or uncontrolled diabetes.
Advice From The Pharmacist
- Make sure to stay well hydrated while using Diuril.
- You might need to adjust your diet to include more potassium. Diuril can cause a loss of potassium in the urine.
- It's best to take Diuril in the morning. Taking it later in the day might make you urinate more frequently during the night.
- Regular doctor appointments and lab tests are important to check your electrolytes and kidney function.
- Always take your medication as directed by your healthcare provider.
Side Effects of Diuril
Common Side Effects
- You might feel thirsty and run to the bathroom more often.
- You might experience muscle cramps, nausea, or vomiting.
Uncommon/Severe Side Effects
- Uncommon side effects:
- You might feel lightheaded, especially when standing up quickly.
- You might experience headaches or changes in vision.
- Rare side effects:
- You might experience a rash or other signs of an allergic reaction.
- Severe side effects:
- If you experience excessive weakness, severe nausea or vomiting, or signs of an allergic reaction, such as difficulty breathing or swelling of the face, lips, tongue, or throat, seek medical attention immediately.
Risks and Warnings of Diuril
- Similar to other medications, Diuril also carries risks and isn?t suitable for everyone. Those with allergies to sulfabased medications, anuria, or severe kidney disease should avoid this drug.
- This drug should be used cautiously in individuals with liver disease or uncontrolled diabetes.
- Pregnant or breastfeeding women should consult with their healthcare provider before taking Diuril.
- People with Addison's disease or certain types of kidney disorders should consult their healthcare provider before taking this medication.
Interactions with Diuril
Common Drug Interactions
- Digitalis
- Lithium
- Anticoagulants
- Insulin or oral diabetes medications
- Other high blood pressure medications
Alternatives to Diuril
- Hydrochlorothiazide
- Furosemide
- Bumetanide
- Ethacrynic Acid
- Torsemide
