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Dextroamphetamine Sulfate ER
Dextroamphetamine Sulfate ER is an extended-release central nervous system (CNS) stimulant used to treat attention-deficit hyperactivity disorder (ADHD) and narcolepsy. It helps increase focus, attention, and alertness by raising the levels of dopamine and norepinephrine in the brain. The extended-release formulation provides long-lasting effects, requiring once-daily dosing, which helps manage symptoms throughout the day.
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Frequently Asked Questions
How long does it take for Dextroamphetamine Sulfate ER to start working?
Effects usually begin within 30 to 60 minutes after taking the medication, with extended-release formulations lasting up to 12 hours.
Can I stop taking Dextroamphetamine Sulfate ER suddenly?
Stopping this medication abruptly may cause withdrawal symptoms such as fatigue, depression, and irritability. Always consult your healthcare provider before discontinuing.
What should I do if I miss a dose?
Take the missed dose as soon as you remember, unless it is close to the time of your next dose. Do not take an extra dose to make up for the missed one.
Does Dextroamphetamine Sulfate ER affect sleep?
Yes, this medication can cause insomnia, particularly if taken late in the day. To minimize sleep disturbances, take it in the morning as prescribed.
Is Dextroamphetamine Sulfate ER safe for long-term use?
When used as prescribed and monitored by a healthcare provider, Dextroamphetamine Sulfate ER is generally safe for long-term use. Regular check-ups are important to monitor for side effects and ensure continued effectiveness.
Comprehensive Drug Guide
How Does Dextroamphetamine Sulfate ER Work?
Dextroamphetamine Sulfate ER works by increasing the availability of dopamine and norepinephrine in the brain. These neurotransmitters play a key role in regulating mood, focus, and alertness. By boosting their levels, dextroamphetamine enhances concentration, reduces hyperactivity, and promotes wakefulness, especially in individuals with ADHD and narcolepsy.
What is Dextroamphetamine Sulfate ER Used For?
- Treatment of ADHD in children and adults
- Treatment of narcolepsy
Common Dosages
Dextroamphetamine Sulfate ER is available in the following strengths:
- 5 mg extended-release capsules
- 10 mg extended-release capsules
- 15 mg extended-release capsules
Typical Dosing
FDA Approved Indications
- For ADHD, the typical starting dose is 10 mg once daily, with adjustments made in 5 mg to 10 mg increments weekly, based on response and tolerance.
- For narcolepsy, the usual starting dose is 10 mg once daily, with adjustments as needed.
Who Shouldn't Take Dextroamphetamine Sulfate ER?
Dextroamphetamine Sulfate ER should not be used in individuals with:
- Advanced arteriosclerosis
- Severe hypertension
- Hyperthyroidism
- Glaucoma
- Severe anxiety or agitation
- History of drug abuse
- Use of monoamine oxidase inhibitors (MAOIs) or within 14 days of stopping MAOI therapy
Advice From The Pharmacist
- Take Dextroamphetamine Sulfate ER once daily in the morning to avoid sleep disturbances, as the medication can interfere with sleep when taken later in the day.
- Avoid consuming caffeine or other stimulants while taking this medication, as they can increase the risk of side effects such as nervousness and increased heart rate.
- Regularly monitor blood pressure and heart rate, as stimulants can raise both. Report any significant increases to your healthcare provider.
- Children on this medication should have their height and weight monitored regularly to ensure proper growth, as appetite suppression can lead to weight loss.
Side Effects of Dextroamphetamine Sulfate ER
Common Side Effects
- Decreased appetite
- Insomnia
- Dry mouth
- Headache
- Stomach pain
- Restlessness
Uncommon/Severe Side Effects
- Increased blood pressure or heart rate
- Psychiatric symptoms, such as new or worsening aggression or hostility
- Heart-related problems, including chest pain or shortness of breath
- Growth suppression in children with long-term use
Risks and Warnings of Dextroamphetamine Sulfate ER
- Abuse and Dependence: Dextroamphetamine Sulfate ER has a high potential for abuse and dependence, especially in individuals with a history of substance abuse. Take the medication exactly as prescribed, and do not share it with others.
- Cardiovascular Effects: Stimulants can raise blood pressure and heart rate. Individuals with pre-existing heart conditions should be closely monitored, and the medication should be used with caution.
- Growth Suppression: In children, long-term use of stimulant medications can affect growth. Regular monitoring of height and weight is recommended during treatment.
Interactions with Dextroamphetamine Sulfate ER
Common Drug Interactions
- Monoamine oxidase inhibitors (MAOIs): Using dextroamphetamine with MAOIs can cause dangerous interactions, including a hypertensive crisis.
- Antihypertensive medications: Dextroamphetamine may reduce the effectiveness of blood pressure-lowering medications.
- Proton pump inhibitors (PPIs): These may alter the absorption of dextroamphetamine and affect its efficacy.
Alternatives to Dextroamphetamine Sulfate ER
- Mixed Amphetamine Salts (Adderall XR): A combination of amphetamine salts used to treat ADHD and narcolepsy.
- Methylphenidate (Concerta, Ritalin LA): A CNS stimulant with similar effects used for ADHD treatment.
- Lisdexamfetamine (Vyvanse): A prodrug stimulant used for ADHD and binge eating disorder, with a lower potential for abuse.
