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Dexedrine
Dexedrine (dextroamphetamine sulfate) is a central nervous system (CNS) stimulant used to treat attention deficit hyperactivity disorder (ADHD) and narcolepsy. It helps increase focus, attention, and impulse control in people with ADHD by affecting the levels of certain neurotransmitters in the brain. Dexedrine is also used to help people with narcolepsy stay awake during the day.
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Frequently Asked Questions
How long does it take for Dexedrine to start working?
Dexedrine typically starts working within 30 minutes to 1 hour after taking it, with its effects lasting for several hours.
Can Dexedrine cause weight loss?
Yes, weight loss is a common side effect of Dexedrine due to its appetite-suppressing effects.
What should I do if I miss a dose of Dexedrine?
If you miss a dose, take it as soon as you remember. If it’s late in the day, skip the missed dose to avoid insomnia. Do not double up on doses.
Can Dexedrine cause addiction?
Yes, Dexedrine has a high potential for addiction, especially if misused or taken in higher doses than prescribed. It is important to use it only as directed by your healthcare provider.
Is Dexedrine safe for long-term use?
Dexedrine can be used long-term if closely monitored by a healthcare provider. However, regular follow-up appointments are essential to assess for side effects or potential misuse.
Comprehensive Drug Guide
How Does Dexedrine Work?
Dexedrine works by increasing the levels of dopamine and norepinephrine in the brain, which helps improve focus, attention, and impulse control. These neurotransmitters play a key role in regulating behavior and are often imbalanced in individuals with ADHD.
Common Dosages
- Immediate-release tablets: 5 mg, 10 mg
- Extended-release capsules (Dexedrine Spansules): 5 mg, 10 mg, 15 mg
Typical Dosing
- For ADHD: The typical starting dose is 5 mg once or twice daily, with gradual dose increases as needed. The maximum daily dose is 40 mg.
- For narcolepsy: The typical starting dose is 10 mg once daily, with gradual dose increases depending on response and tolerance.
Typical Dosing
FDA Approved Indications
- ADHD in children and adults.
- Narcolepsy in adults and adolescents.
Who Shouldn't Take Dexedrine?
- Known hypersensitivity to dextroamphetamine or any component of the formulation.
- Cardiovascular disease or high blood pressure.
- Hyperthyroidism or glaucoma.
- History of drug abuse.
Advice From The Pharmacist
- Take Dexedrine early in the day to avoid insomnia or trouble sleeping.
- Do not increase the dose without consulting your healthcare provider, as this medication has a high potential for abuse.
- Store Dexedrine in a safe place to prevent misuse or theft, as it is a controlled substance.
Side Effects of Dexedrine
Common Side Effects
- Increased heart rate
- Elevated blood pressure
- Dry mouth
- Loss of appetite
- Insomnia
Uncommon/Severe Side Effects
- Heart problems (chest pain, heart attack)
- Stroke
- Psychosis or hallucinations
- Aggressive behavior
Risks and Warnings of Dexedrine
- Abuse Potential: Dexedrine has a high potential for abuse, dependence, and addiction. It should be used only as prescribed and for the shortest duration necessary.
- Cardiovascular Risks: Methamphetamine stimulants like Dexedrine can increase heart rate and blood pressure, leading to serious heart problems such as heart attack or stroke, especially in patients with pre-existing conditions.
- Psychiatric Effects: Dexedrine can exacerbate psychosis, mania, or aggressive behavior in individuals with pre-existing mental health conditions.
Interactions with Dexedrine
Common Drug Interactions
- Monoamine oxidase inhibitors (MAOIs): Taking Dexedrine with MAOIs can cause a dangerous increase in blood pressure and should be avoided.
- Antihypertensives: Dexedrine may reduce the effectiveness of blood pressure-lowering medications.
- Other stimulants: Combining Dexedrine with other CNS stimulants (e.g., Adderall, Ritalin) increases the risk of side effects, such as high blood pressure and heart problems.
Alternatives to Dexedrine
- Adderall (amphetamine/dextroamphetamine): A similar stimulant medication commonly used to treat ADHD.
- Ritalin (methylphenidate): Another stimulant frequently used for ADHD and narcolepsy.
- Strattera (atomoxetine): A non-stimulant option for ADHD.
