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Dexchlorpheniramine Maleate
Dexchlorpheniramine Maleate is an antihistamine used to treat symptoms of allergic conditions such as hay fever, allergic rhinitis, urticaria (hives), and other allergic reactions. As a first-generation antihistamine, it helps alleviate symptoms like runny nose, sneezing, itchy or watery eyes, and itchy throat by blocking the effects of histamine, a chemical in the body that causes allergic symptoms.
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Frequently Asked Questions
How quickly does Dexchlorpheniramine Maleate start working?
You may begin to feel relief from allergic symptoms within 30 to 60 minutes of taking the medication.
Can I take Dexchlorpheniramine Maleate with other allergy medications?
It is best to consult your healthcare provider before combining this medication with other allergy treatments, as it may increase the risk of drowsiness or other side effects.
Is Dexchlorpheniramine Maleate safe for long-term use?
This medication is generally safe for short-term use. For long-term allergy management, non-sedating antihistamines may be a better option. Always consult your healthcare provider for extended use.
Can Dexchlorpheniramine Maleate cause weight gain?
Weight gain is not a common side effect, but the drowsiness it causes may result in reduced physical activity in some individuals.
What should I do if I miss a dose?
If you miss a dose, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose and continue your regular schedule. Do not take a double dose.
Comprehensive Drug Guide
How Does Dexchlorpheniramine Maleate Work?
Dexchlorpheniramine Maleate works by blocking histamine H1 receptors, preventing histamine from binding to these receptors in the body. Histamine is a chemical that is released during allergic reactions and causes symptoms such as itching, swelling, and runny nose. By inhibiting histamine activity, this medication provides relief from allergic symptoms.
What is Dexchlorpheniramine Maleate Used For?
- Relief of allergy symptoms, including sneezing, runny nose, itchy or watery eyes, and throat irritation
- Treatment of allergic skin reactions (e.g., hives, itching)
Common Dosages
Dexchlorpheniramine Maleate is available in the following strengths:
- Tablets: 2 mg, 4 mg, and 6 mg
- Syrup: 2 mg/5 mL
Typical Dosing
FDA Approved Indications
For adults and children aged 12 years and older, the usual dose is 2 mg to 6 mg every 4 to 6 hours, not exceeding 24 mg per day.
Pediatric Dosing
For children aged 6 to 11 years, the typical dose is 2 mg every 4 to 6 hours, with a maximum of 12 mg per day.
Who Shouldn't Take Dexchlorpheniramine Maleate?
Dexchlorpheniramine Maleate should not be used in individuals with:
- Narrow-angle glaucoma
- Severe hypertension or coronary artery disease
- Bladder neck obstruction
- Known hypersensitivity to dexchlorpheniramine or other antihistamines
- MAOI therapy (within 14 days of taking monoamine oxidase inhibitors)
Advice From The Pharmacist
- Take Dexchlorpheniramine Maleate with or without food, but taking it with food may help reduce stomach upset.
- Avoid consuming alcohol while on this medication, as it can increase drowsiness.
- Be cautious when performing tasks that require alertness, such as driving or operating machinery, as dexchlorpheniramine can cause drowsiness or dizziness.
- Store the medication at room temperature and away from excessive heat and moisture.
Side Effects of Dexchlorpheniramine Maleate
Common Side Effects
- Drowsiness
- Dry mouth
- Dizziness
- Blurred vision
- Difficulty urinating
Uncommon/Severe Side Effects
- Severe allergic reactions (e.g., rash, swelling, difficulty breathing)
- Confusion or agitation, especially in elderly patients
- Fast or irregular heartbeat
Risks and Warnings of Dexchlorpheniramine Maleate
Drowsiness: As a first-generation antihistamine, Dexchlorpheniramine Maleate can cause significant drowsiness and impair your ability to perform activities that require alertness. Avoid alcohol and other sedatives while taking this medication.
Anticholinergic Effects: This medication may cause dry mouth, constipation, and difficulty urinating. Elderly patients are particularly sensitive to these effects and should be monitored closely.
Use in Children: In young children, this medication may cause excitement or hyperactivity rather than sedation. Use with caution and under medical supervision.
Interactions with Dexchlorpheniramine Maleate
Common Drug Interactions
- Alcohol and sedatives: Combining Dexchlorpheniramine Maleate with alcohol, sleeping pills, or sedatives can increase drowsiness and slow reaction times.
- Monoamine oxidase inhibitors (MAOIs): Combining with MAOIs can cause serious drug interactions, including hypertensive crisis.
- Anticholinergic drugs: Combining with other drugs that have anticholinergic effects can increase the risk of side effects like dry mouth, constipation, or difficulty urinating.
Alternatives to Dexchlorpheniramine Maleate
- Diphenhydramine (Benadryl): Another first-generation antihistamine commonly used to treat allergic reactions.
- Loratadine (Claritin): A second-generation antihistamine that causes less drowsiness and is used to treat allergies.
- Cetirizine (Zyrtec): A second-generation antihistamine used for allergic conditions with minimal sedative effects.
- Fexofenadine (Allegra): A non-sedating antihistamine for the treatment of seasonal allergies.
