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DermacinRx PHN

DermacinRx PHN is a topical analgesic used to provide relief from postherpetic neuralgia (PHN), a condition characterized by nerve pain following an outbreak of shingles. It contains lidocaine and other ingredients designed to numb the skin and alleviate pain. By delivering localized pain relief, DermacinRx PHN helps patients manage the discomfort associated with PHN, making daily activities more manageable.

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Frequently Asked Questions

How quickly does DermacinRx PHN provide pain relief?
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Relief from pain can occur within minutes to an hour after applying the cream or patch, depending on the severity of the pain and the individual’s response.

Can I shower or bathe with the patch on?
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It is generally recommended to remove the patch before bathing or swimming, as water can affect its adherence and effectiveness.

How long should I use DermacinRx PHN for postherpetic neuralgia?
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Your healthcare provider will determine the appropriate duration of treatment based on your symptoms. Some patients may use it for weeks or months, depending on the severity of their pain.

Is it safe to apply DermacinRx PHN multiple times a day?
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Yes, the cream can be applied 3-4 times daily as needed, and the patch is typically used for 12 hours on, 12 hours off. Follow your healthcare provider’s instructions and avoid exceeding the recommended dosage.

What should I do if I experience skin irritation from DermacinRx PHN?
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If you experience mild skin irritation, try reducing the frequency of application. If the irritation is severe or persists, discontinue use and consult your healthcare provider.

Comprehensive Drug Guide

How Does DermacinRx PHN Work?

The primary active ingredient in DermacinRx PHN is lidocaine, a local anesthetic that blocks sodium channels in nerve cells. This action inhibits the transmission of pain signals from the affected area to the brain, providing temporary relief from the nerve pain associated with postherpetic neuralgia.



What is DermacinRx PHN Used For?

  • Relief of pain associated with postherpetic neuralgia (PHN)

Common Dosages

DermacinRx PHN is typically available in the following forms:

  • Topical cream: Contains lidocaine in varying concentrations, usually 5%
  • Topical patch: Often contains 5% lidocaine

Typical Dosing

FDA Approved Indications

  • For the cream: Apply a thin layer to the affected area up to 3-4 times daily as needed for pain relief.
  • For the patch: Apply one patch to the affected area for 12 hours, then remove for the next 12 hours. Do not exceed one patch per 24-hour period unless directed by a healthcare provider.


Who Shouldn't Take DermacinRx PHN?

DermacinRx PHN should not be used in individuals with:

  • Known hypersensitivity to lidocaine or other local anesthetics
  • Severe liver disease (due to potential systemic absorption)
  • Open wounds or damaged skin in the area where the cream or patch is applied


Advice From The Pharmacist

  • Apply DermacinRx PHN only to intact skin. Avoid applying to open wounds or irritated skin to reduce the risk of increased absorption and side effects.
  • Wash your hands before and after applying the cream or patch.
  • Do not apply heat (such as a heating pad) over the patch or cream, as this may increase the risk of lidocaine absorption and cause toxicity.
  • If using the patch, ensure it adheres fully to the skin, and follow the 12-hour on/12-hour off regimen to avoid overexposure.


Side Effects of DermacinRx PHN

Common Side Effects

  • Mild skin irritation or redness at the application site
  • Temporary numbness or tingling


Uncommon/Severe Side Effects

  • Signs of allergic reaction (e.g., rash, swelling, difficulty breathing)
  • Severe skin reactions (e.g., blistering, peeling)
  • Systemic effects from excessive lidocaine absorption (e.g., dizziness, irregular heartbeat)


Risks and Warnings of DermacinRx PHN

Systemic Lidocaine Toxicity: Although rare, excessive use of topical lidocaine can lead to systemic absorption, which may cause serious side effects, including seizures, irregular heartbeats, or respiratory depression. Follow the dosing instructions carefully.

Skin Reactions: Prolonged use of the cream or patch may cause skin irritation or hypersensitivity reactions. Discontinue use and contact your healthcare provider if severe irritation occurs.


Interactions with DermacinRx PHN

Common Drug Interactions

  • Other local anesthetics: Using other lidocaine-containing products or anesthetics alongside DermacinRx PHN may increase the risk of systemic toxicity.
  • Class I antiarrhythmic drugs: Lidocaine may interact with medications like mexiletine, which are used to treat heart arrhythmias.


Alternatives to DermacinRx PHN

  • Lidoderm Patch: A 5% lidocaine patch commonly used for postherpetic neuralgia.
  • Capsaicin cream: A topical pain reliever that works by reducing the sensitivity of pain receptors in the skin.
  • Gabapentin: An oral medication used to treat nerve pain associated with PHN.

Pregabalin: Another oral medication for nerve pain in postherpetic neuralgia patients.