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Clobex Spray
Clobex Spray is a super-high potency topical corticosteroid that contains clobetasol propionate. It is specifically formulated to treat moderate to severe plaque psoriasis in patients over 18 years of age. The spray form allows for easy application over larger areas of the body, making it convenient for patients who need to treat extensive or hard-to-reach patches of skin. Clobex Spray helps reduce inflammation, redness, and itching associated with psoriasis flare-ups. It is intended for short-term use due to its high potency.
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Frequently Asked Questions
How long does it take for Clobex Spray to work?
Most patients begin to see improvement within 1 to 2 weeks of starting treatment. However, it is important not to use Clobex Spray for more than 4 weeks without medical supervision.
Can Clobex Spray be used on the face?
Clobex Spray should not be used on the face unless specifically directed by your healthcare provider. It is a super-high potency steroid and can cause skin thinning and other side effects when applied to facial skin.
What should I do if I miss a dose?
If you miss a dose, apply it as soon as you remember. If it’s close to the time for your next dose, skip the missed dose and continue your regular schedule. Do not double up on doses.
Is Clobex Spray safe for children?
Clobex Spray is not recommended for use in children under 18 years of age due to the risk of side effects such as skin thinning and adrenal suppression.
Can I use Clobex Spray for long-term treatment?
No, Clobex Spray is not intended for long-term use. It should only be used for short-term treatment of flare-ups and is usually limited to 4 weeks or less. If long-term management is needed, your healthcare provider may recommend alternative treatments.
Comprehensive Drug Guide
How Does Clobex Spray Work?
Clobex Spray works by inhibiting the release of pro-inflammatory substances such as prostaglandins and leukotrienes. This suppression helps reduce inflammation, itching, and redness associated with plaque psoriasis. The spray form allows for uniform application to larger areas of the skin, reducing irritation and inflammation.
Common Dosages
Clobex Spray is available in the following strength:
- Spray: 0.05% clobetasol propionate
Typical Dosing
- For adults: Spray a thin layer onto the affected area twice daily. Do not use for more than 4 weeks unless instructed by your healthcare provider. Avoid using the spray on the face, groin, or underarms, as it is not suitable for these sensitive areas.
Typical Dosing
FDA Approved Indications
Moderate to severe plaque psoriasis in adults aged 18 years and older
Who Shouldn't Take Clobex Spray?
- Known hypersensitivity to clobetasol or any component of the formulation
- Bacterial, fungal, or viral skin infections
- Rosacea or perioral dermatitis
Advice From The Pharmacist
- Shake the Clobex Spray bottle well before each use and apply only to clean, dry skin.
- Avoid spraying on broken skin or open wounds. If you accidentally get the spray on the face, eyes, or mouth, rinse thoroughly with water.
- Do not cover the treated area with bandages or occlusive dressings unless directed by your healthcare provider, as this may increase absorption and side effects.
- Use the spray only for the prescribed duration. Prolonged use can lead to skin thinning or other adverse effects.
- Discontinue use if your symptoms improve before the end of the prescribed course, but consult your doctor before stopping the medication.
Side Effects of Clobex Spray
Common Side Effects
- Burning or stinging sensation at the application site
- Dryness, peeling, or cracking of the skin
- Skin thinning or stretch marks with prolonged use
Uncommon/Severe Side Effects
- Skin infections due to weakened immune response
- Skin discoloration or atrophy
- Adrenal suppression if used on large areas of the body for extended periods
Risks and Warnings of Clobex Spray
- Adrenal Suppression: Clobex Spray is a potent corticosteroid, and prolonged use can lead to adrenal suppression. This may result in symptoms like fatigue, weight loss, and low blood pressure. Always follow your healthcare provider’s instructions and avoid using Clobex for more than 4 weeks.
- Skin Atrophy: Long-term use of Clobex Spray can lead to thinning of the skin, stretch marks, and visible blood vessels. Avoid using it on sensitive areas like the face and groin.
- Infection Risk: Clobex may increase the risk of skin infections due to its immunosuppressive properties. If you notice signs of infection (such as redness, swelling, or pus), discontinue use and consult your healthcare provider.
Interactions with Clobex Spray
Common Drug Interactions
- Other Topical Medications: Using Clobex Spray with other topical treatments, such as retinoids or salicylic acid, may increase skin irritation.
- Systemic Corticosteroids: Concurrent use of Clobex Spray with oral or injectable corticosteroids may increase the risk of systemic side effects, such as adrenal suppression.
Alternatives to Clobex Spray
- Betamethasone Dipropionate (Diprolene): A potent corticosteroid for treating similar skin conditions.
- Triamcinolone Acetonide (Kenalog): A mid-potency corticosteroid for managing inflammatory skin conditions.
- Calcipotriene (Dovonex): A non-steroidal topical medication for treating psoriasis that helps regulate skin cell production.
