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Clemastine Fumarate
Clemastine Fumarate is an antihistamine used to relieve symptoms of allergies, hay fever, and the common cold. It is effective in treating symptoms such as sneezing, runny nose, watery eyes, and itching. Clemastine Fumarate belongs to the first-generation antihistamines class, meaning it can cause drowsiness, but it also provides rapid relief for allergic reactions. It is available in both over-the-counter and prescription forms, typically in tablet and syrup formulations.
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Frequently Asked Questions
How long does it take for Clemastine Fumarate to work?
Clemastine Fumarate generally begins to work within 30 minutes to 1 hour after taking a dose, providing relief for up to 12 hours.
Can I take Clemastine Fumarate with other medications?
Always check with your healthcare provider before combining Clemastine with other medications, especially sedatives, alcohol, or medications for anxiety, sleep, or seizures.
Does Clemastine Fumarate cause drowsiness?
Yes, Clemastine Fumarate is a first-generation antihistamine, which can cause drowsiness. Use caution when driving or operating machinery after taking it.
Can I take Clemastine Fumarate daily for allergies?
Clemastine Fumarate can be used daily for short-term relief of allergies, but long-term use should be under the guidance of a healthcare provider to monitor for side effects.
Is Clemastine Fumarate safe for children?
Yes, Clemastine Fumarate can be used in children 6 years and older, but dosing should always be supervised by a healthcare provider. Children under 6 years should not use it without specific medical advice.
Comprehensive Drug Guide
How Does Clemastine Fumarate Work?
Clemastine Fumarate works by blocking the effects of histamine, a substance in the body that causes allergic symptoms. By inhibiting histamine receptors, Clemastine prevents allergic reactions such as itching, swelling, and hives, providing relief from symptoms associated with allergies and the common cold.
Common Dosages
Clemastine Fumarate is available in the following forms and strengths:
- Tablets: 1.34 mg, 2.68 mg
- Syrup: 0.5 mg/5 mL
Typical Dosing
- For adults and children over 12 years: The usual dose is 1.34 mg to 2.68 mg twice a day.
- For children aged 6 to 12 years: 0.67 mg twice a day (under medical supervision).
- For children under 6 years: Dosing is determined by a healthcare provider.
Typical Dosing
FDA Approved Indications
- Allergic rhinitis (hay fever)
- Urticaria (hives)
- Cold symptoms (runny nose, sneezing, itchy/watery eyes)
- Allergic skin reactions
Who Shouldn't Take Clemastine Fumarate?
- Hypersensitivity or allergy to Clemastine or any of its components
- Newborns or premature infants
- Breastfeeding mothers (due to the risk of sedative effects on the infant)
- Individuals with asthma (use with caution)
- Patients with glaucoma or difficulty urinating due to enlarged prostate
Advice From The Pharmacist
Side Effects of Clemastine Fumarate
Common Side Effects
- Drowsiness
- Dry mouth
- Dizziness
- Headache
- Blurred vision
Uncommon/Severe Side Effects
- Difficulty urinating
- Fast or irregular heartbeat
- Severe drowsiness or confusion
- Allergic reactions (rash, swelling, difficulty breathing)
Risks and Warnings of Clemastine Fumarate
- Drowsiness: Clemastine Fumarate is a first-generation antihistamine and can cause significant drowsiness. Use caution when driving or engaging in activities requiring alertness.
- Alcohol and Sedatives: Alcohol and other sedative medications should be avoided when taking Clemastine, as the combination can lead to increased drowsiness and sedation.
- Glaucoma: Clemastine may increase intraocular pressure, making it unsuitable for individuals with glaucoma.
- Elderly Patients: Older adults may be more sensitive to the sedative effects of Clemastine and should use lower doses under medical supervision.
Interactions with Clemastine Fumarate
Common Drug Interactions
- Sedatives: Clemastine enhances the sedative effects of medications such as benzodiazepines, opioids, and sleep aids. Use with caution and under medical advice.
- Alcohol: Consuming alcohol while taking Clemastine may exacerbate drowsiness and other side effects.
- Anticholinergic Drugs: Combining Clemastine with other anticholinergic medications (e.g., atropine, scopolamine) may increase the risk of side effects such as dry mouth, constipation, and difficulty urinating.
Alternatives to Clemastine Fumarate
- Loratadine (Claritin): A second-generation antihistamine that does not typically cause drowsiness.
- Cetirizine (Zyrtec): Another second-generation antihistamine, often used for allergies and with less drowsiness compared to Clemastine.
- Diphenhydramine (Benadryl): A first-generation antihistamine similar to Clemastine, used for allergies and cold symptoms but with a stronger sedative effect.
- Fexofenadine (Allegra): A non-drowsy antihistamine option for allergy relief.
