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Clarinex-D 12 Hour
Clarinex-D 12 Hour is a combination medication used to treat symptoms of seasonal allergies, such as sneezing, runny nose, itchy or watery eyes, and nasal congestion. It contains desloratadine, an antihistamine, and pseudoephedrine, a decongestant. Desloratadine helps relieve allergy symptoms by blocking histamine, while pseudoephedrine works to relieve nasal congestion by constricting blood vessels in the nasal passages. Clarinex-D 12 Hour is designed for twice-daily dosing to provide relief from allergy symptoms throughout the day.
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Frequently Asked Questions
How long does Clarinex-D 12 Hour take to start working?
Most patients begin to experience relief from allergy symptoms within 1 to 2 hours of taking Clarinex-D 12 Hour. The medication is designed to provide symptom relief for up to 12 hours.
Can I take Clarinex-D 12 Hour at night?
It is best to avoid taking Clarinex-D 12 Hour close to bedtime, as the pseudoephedrine component may cause insomnia or difficulty sleeping.
What should I do if I miss a dose of Clarinex-D 12 Hour?
If you miss a dose, take it as soon as you remember. If it is close to the time of your next dose, skip the missed dose and resume your regular dosing schedule. Do not take two doses at once.
Can I take Clarinex-D 12 Hour with high blood pressure?
Clarinex-D 12 Hour contains pseudoephedrine, which can elevate blood pressure. If you have high blood pressure or heart disease, consult your healthcare provider before using this medication.
Comprehensive Drug Guide
How Does Clarinex-D 12 Hour Work?
- Desloratadine: A long-acting antihistamine that blocks histamine receptors, preventing the allergic response. It relieves symptoms like sneezing, itching, and watery eyes without causing significant drowsiness.
- Pseudoephedrine: A nasal decongestant that constricts blood vessels in the nasal passages, reducing swelling and congestion, allowing for easier breathing.
Common Dosages
- Extended-release tablet: 2.5 mg desloratadine/120 mg pseudoephedrine
Typical Dosing
- For adults and children over 12 years: Take one tablet twice daily, with or without food. Do not exceed two tablets in 24 hours.
Typical Dosing
FDA Approved Indications
Seasonal allergic rhinitis (hay fever) with nasal congestion
Who Shouldn't Take Clarinex-D 12 Hour?
- Hypersensitivity or allergy to desloratadine, pseudoephedrine, or other sympathomimetics
- Severe hypertension (high blood pressure) or coronary artery disease
- Use within 14 days of taking monoamine oxidase inhibitors (MAOIs)
- Narrow-angle glaucoma, urinary retention, or severe kidney disease
Advice From The Pharmacist
- Take Clarinex-D 12 Hour with or without food, but avoid taking it close to bedtime, as pseudoephedrine may cause insomnia.
- Swallow the tablet whole; do not crush or chew it, as it is designed for extended release over 12 hours.
- If you experience dry mouth, headaches, or difficulty sleeping, consider reducing caffeine intake while using this medication, as it may increase the risk of these side effects.
- Avoid using other over-the-counter decongestants or antihistamines while taking Clarinex-D 12 Hour to prevent doubling up on ingredients.
Side Effects of Clarinex-D 12 Hour
Common Side Effects
- Dry mouth
- Dizziness
- Headache
- Insomnia
- Nervousness or restlessness
- Severe allergic reactions (rash, swelling, difficulty breathing)
- Elevated blood pressure or rapid heartbeat
- Urinary retention, particularly in men with enlarged prostate
- Confusion or hallucinations
Uncommon/Severe Side Effects
- Severe allergic reactions (rash, swelling, difficulty breathing)
- Elevated blood pressure or rapid heartbeat
- Urinary retention, particularly in men with enlarged prostate
- Confusion or hallucinations
Risks and Warnings of Clarinex-D 12 Hour
- Insomnia: Due to the presence of pseudoephedrine, Clarinex-D 12 Hour may cause insomnia or difficulty sleeping if taken close to bedtime.
- Cardiovascular Effects: Pseudoephedrine can elevate blood pressure and heart rate. Patients with a history of high blood pressure, heart disease, or arrhythmias should consult their healthcare provider before using Clarinex-D 12 Hour.
- Urinary Retention: Men with an enlarged prostate or individuals with urinary retention should use Clarinex-D 12 Hour with caution, as pseudoephedrine can exacerbate these conditions.
Interactions with Clarinex-D 12 Hour
Common Drug Interactions
- Monoamine Oxidase Inhibitors (MAOIs): Using Clarinex-D 12 Hour within 14 days of taking an MAOI can cause dangerous increases in blood pressure.
- Beta-blockers: Pseudoephedrine may reduce the effectiveness of beta-blockers and increase blood pressure.
- Other Decongestants: Avoid combining Clarinex-D 12 Hour with other products containing decongestants, as this can increase the risk of side effects like elevated blood pressure or rapid heart rate.
Alternatives to Clarinex-D 12 Hour
- Loratadine-Pseudoephedrine (Claritin-D): Another combination of antihistamine and decongestant used for seasonal allergies with similar effectiveness.
- Cetirizine-Pseudoephedrine (Zyrtec-D): A combination medication that provides long-lasting relief from allergy symptoms and congestion.
- Fexofenadine-Pseudoephedrine (Allegra-D): Another non-drowsy antihistamine combined with a decongestant for relief of allergy symptoms and congestion.
