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Cipro HC
Cipro HC (Ciprofloxacin and Hydrocortisone) is a combination medication used to treat acute otitis externa, commonly known as swimmer’s ear. It combines ciprofloxacin, a fluoroquinolone antibiotic, and hydrocortisone, a corticosteroid. Ciprofloxacin works by inhibiting the growth of bacteria causing the infection, while hydrocortisone helps reduce inflammation, redness, and discomfort in the ear. Cipro HC is available as an otic suspension (ear drops) and is typically prescribed for short-term use to resolve bacterial infections and related inflammation in the outer ear.
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Frequently Asked Questions
How long does it take for Cipro HC to work?
Most patients begin to notice improvement in symptoms within 2 to 3 days of starting treatment. However, it is important to complete the full course, typically 7 days, to ensure the infection is fully resolved.
Can I use Cipro HC for a fungal or viral ear infection?
No, Cipro HC is only effective against bacterial infections. It will not work for fungal or viral infections. Your doctor will prescribe an appropriate treatment based on the cause of your ear infection.
What should I do if I miss a dose of Cipro HC?
If you miss a dose, apply it as soon as you remember. If it is close to your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose.
Can I swim while using Cipro HC?
No, it is recommended to avoid swimming or getting water in the affected ear while treating an infection with Cipro HC. Water exposure can delay healing and potentially worsen the infection.
Is Cipro HC safe for children?
Yes, Cipro HC is safe for children over the age of 1 year, but always follow your healthcare provider’s dosing instructions carefully.
Comprehensive Drug Guide
How Does Cipro HC Work?
Cipro HC contains ciprofloxacin, which inhibits bacterial DNA gyrase and topoisomerase IV, enzymes critical for bacterial DNA replication and repair. This action kills the bacteria causing the infection. Hydrocortisone, a corticosteroid, works by reducing inflammation, swelling, and redness in the ear, helping to alleviate symptoms while the infection clears.
Common Dosages
- Otic Suspension: Each mL contains 0.2% ciprofloxacin and 1% hydrocortisone.
Typical Dosing
- For otitis externa: Instill 3 drops into the affected ear twice daily for 7 days. The dosing may vary based on the severity of the infection, but it is important to follow the prescribed course to ensure complete resolution.
Typical Dosing
FDA Approved Indications
Acute otitis externa (swimmer's ear) caused by susceptible bacteria
Who Shouldn't Take Cipro HC?
- Hypersensitivity to ciprofloxacin, hydrocortisone, or other quinolone antibiotics
- Viral or fungal ear infections
- Perforated eardrum (as it may cause damage to the middle ear)
Advice From The Pharmacist
- Warm the bottle of Cipro HC in your hands for a few minutes before using it to prevent dizziness when cold drops are instilled in the ear.
- Tilt your head or lie down with the affected ear facing upward, and stay in this position for a few minutes after applying the drops to allow proper absorption.
- Avoid swimming or getting water in the affected ear while using Cipro HC.
- Complete the full course of treatment, even if symptoms improve early, to prevent a return of the infection.
- Do not use Cipro HC for viral or fungal infections of the ear.
Side Effects of Cipro HC
Common Side Effects
- Mild ear discomfort or itching after application
- Temporary stinging or burning sensation in the ear
- Dryness or scaling of the skin around the ear
Uncommon/Severe Side Effects
- Allergic reactions such as rash, swelling, or difficulty breathing
- Worsening ear pain or hearing changes
- Dizziness or lightheadedness
Risks and Warnings of Cipro HC
- Allergic Reactions: Individuals allergic to fluoroquinolones or corticosteroids should not use Cipro HC. Discontinue use and seek medical attention if an allergic reaction occurs.
- Perforated Eardrum: Cipro HC should not be used if you have a perforated eardrum, as it can cause further damage. Always consult your doctor for a thorough ear examination before starting treatment.
- Superinfection: Prolonged use of Cipro HC may lead to secondary infections, such as fungal or viral ear infections, if bacteria are eradicated but other pathogens are not treated.
Interactions with Cipro HC
Common Drug Interactions
Since Cipro HC is applied topically in the ear, systemic drug interactions are unlikely. However, inform your doctor of all medications, supplements, and herbal products you are using to avoid potential conflicts.
Alternatives to Cipro HC
- Ofloxacin (Floxin Otic): Another fluoroquinolone antibiotic used for bacterial ear infections.
- Ciprofloxacin Otic Solution: A similar antibiotic formulation without corticosteroid for simpler infections.
- Polymyxin B-neomycin-hydrocortisone (Cortisporin Otic): An alternative antibiotic/corticosteroid combination for treating bacterial ear infections and inflammation.
