You're not logged in. Please log in to earn stock or Bitcoin rewards on your prescription purchase.
Cimerli
Cimerli (ranibizumab-eqrn) is a biosimilar to Lucentis used to treat various eye conditions related to abnormal blood vessel growth, such as age-related macular degeneration (AMD), diabetic macular edema (DME), diabetic retinopathy, and macular edema following retinal vein occlusion. It works by inhibiting vascular endothelial growth factor A (VEGF-A), reducing abnormal blood vessel growth and leakage in the retina, thus helping to preserve vision.
Oops! We currently don’t have the pricing information for this drug.
But we're continually improving our service to help you save and earn rebates on your medications. If your drug isn't listed on NiHowdy, you can still present your NiHowdy savings card at the pharmacy. We'll work to secure any eligible rebates for that drug and pass the savings back to you retroactively.
Members have saved
$NaN
using our savings card for instant savings.
Don't pay full retail price and miss out on potential savings. Try it now—you have nothing to lose!
NaNM
worth of Satoshi has been rewarded to our members.
Everyone who signs up enjoys the benefits of earning FREE Bitcoin with every purchase.
Frequently Asked Questions
How long does it take for Cimerli to start working?
Many patients notice an improvement in vision within the first month of treatment, although full benefits may take several months of regular injections.
How often do I need Cimerli injections?
The standard treatment involves monthly injections, though after the initial treatment period, your doctor may reduce the frequency to once every 2-3 months based on your response.
Is Cimerli painful to receive?
Cimerli is injected directly into the eye, but your doctor will numb your eye beforehand to minimize discomfort. Some patients experience mild discomfort or pressure during the injection.
What should I do if I experience vision changes after receiving Cimerli?
If you experience sudden changes in vision, such as blurred vision, flashes of light, or floaters, contact your healthcare provider immediately, as this could indicate a serious side effect like retinal detachment or infection.
Can I drive after receiving a Cimerli injection?
Your vision may be temporarily blurred after the injection, so it is advisable to avoid driving or operating heavy machinery until your vision clears.
Comprehensive Drug Guide
How Does Cimerli Work?
Cimerli works by binding to VEGF-A, a protein that stimulates abnormal blood vessel growth in the retina. By blocking VEGF-A, Cimerli prevents the formation of abnormal blood vessels, reduces leakage, and decreases retinal swelling, thereby improving or maintaining vision in patients with certain retinal conditions.
What is Cimerli Used For?
- Neovascular (wet) age-related macular degeneration (AMD)
- Diabetic macular edema (DME)
- Diabetic retinopathy
- Macular edema following retinal vein occlusion (RVO)
Common Dosages
Cimerli is available by prescription in injectable form for administration directly into the eye. It is not classified as a controlled substance.
- 0.5 mg/0.05 mL for intravitreal injection
Typical Dosing
FDA Approved Indications
For most conditions, the typical dose is 0.5 mg injected into the affected eye once per month. Depending on the patient's response, dosing frequency may be reduced after the initial treatment period.
Who Shouldn't Take Cimerli?
Cimerli should not be used in individuals with:
- Ocular or periocular infections
- Active intraocular inflammation
- Known hypersensitivity to ranibizumab or any of the components in the formulation
Advice From The Pharmacist
- Cimerli is administered via intravitreal injection by a healthcare provider. Be sure to attend all scheduled appointments to maintain the treatment’s effectiveness.
- After the injection, you may experience mild discomfort or blurred vision, which should improve over a few days. Report any signs of infection, such as eye redness, pain, or sensitivity to light, to your healthcare provider immediately.
- Avoid rubbing your eyes or swimming for several days after receiving an injection to reduce the risk of infection.
Side Effects of Cimerli
Common Side Effects
- Eye pain or discomfort
- Increased intraocular pressure
- Blurred vision
- Redness or irritation in the eye
Uncommon/Severe Side Effects
- Endophthalmitis (eye infection)
- Retinal detachment
- Severe eye pain or vision changes
- Increased risk of cataracts
Risks and Warnings of Cimerli
Eye Infections: There is a risk of developing serious eye infections (endophthalmitis) after intravitreal injections. Contact your healthcare provider if you experience symptoms such as eye redness, pain, or blurred vision.
Retinal Detachment: Rarely, injections into the eye can cause retinal detachment. Report any sudden changes in vision, such as flashes of light or a curtain-like shadow over your visual field.
Increased Intraocular Pressure: Some patients may experience a temporary increase in eye pressure following an injection. Your healthcare provider will monitor for this after each treatment.
Interactions with Cimerli
Common Drug Interactions
Other intravitreal injections: Concurrent use of other intravitreal injections may increase the risk of complications such as infection or retinal damage.
Blood thinners: Patients taking blood thinners should inform their healthcare provider, as intravitreal injections can increase the risk of bleeding in the eye.
Alternatives to Cimerli
- Lucentis (ranibizumab): The original version of ranibizumab, used for the same conditions as Cimerli.
- Eylea (aflibercept): Another anti-VEGF therapy used for wet AMD, diabetic retinopathy, and macular edema.
- Beovu (brolucizumab): An anti-VEGF medication used for treating wet AMD with less frequent dosing than Lucentis or Cimerli.
