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Balziva

Balziva is a combination oral contraceptive pill (OCP) used to prevent pregnancy. It contains two active ingredients: norethindrone, a progestin, and ethinyl estradiol, an estrogen. These hormones work together to prevent ovulation (the release of an egg from the ovary) and cause changes in the cervical mucus and uterine lining, making it harder for sperm to reach the egg and for a fertilized egg to attach to the uterus. In addition to birth control, Balziva may be prescribed to regulate menstrual cycles, reduce the risk of ovarian cysts, and treat acne.


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Frequently Asked Questions

How effective is Balziva in preventing pregnancy?
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When taken correctly and consistently, Balziva is more than 99% effective in preventing pregnancy. However, missed pills or inconsistent use can decrease its effectiveness.

Can I skip my period by taking Balziva continuously?
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Some women choose to skip their period by starting a new pack of active pills immediately after finishing the active pills in their current pack, skipping the inactive pills. Consult your healthcare provider before doing this to ensure it's safe for you.

What should I do if I miss a pill?
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If you miss a pill, take it as soon as you remember. If you miss more than one pill, follow the instructions provided in the medication guide or contact your healthcare provider for guidance. You may need to use backup contraception.

Is Balziva safe to use while breastfeeding?
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Balziva is generally not recommended for use while breastfeeding, as it can reduce milk production. Progestin-only contraceptives are usually preferred for breastfeeding women.

Can Balziva help with acne?
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Yes, Balziva, like other combined oral contraceptives, can help reduce acne in some women by regulating hormones that contribute to acne formation.

Does Balziva protect against STIs?
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No, Balziva does not protect against sexually transmitted infections (STIs). The use of condoms is recommended to protect against STIs.

Can Balziva be used as emergency contraception?
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Balziva is intended for regular contraceptive use and is not approved for use as an emergency contraceptive. Always consult with your healthcare provider for appropriate options in case of contraception emergencies.

Is it safe to smoke while taking Balziva?
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Smoking increases the risk of serious heart side effects from hormonal birth control pills, including Balziva. The risk increases with age and heavy smoking (15 or more cigarettes per day) and is quite pronounced in women over 35 years.

Comprehensive Drug Guide

How Does Balziva Work?

Mechanism of Action

Balziva works through several mechanisms to prevent pregnancy:

  • Inhibition of Ovulation: Norethindrone and ethinyl estradiol suppress the release of gonadotropins (LH and FSH), preventing the maturation of an egg and its release from the ovary.
  • Thickening of Cervical Mucus: The progestin component thickens the mucus in the cervix, making it difficult for sperm to enter the uterus.
  • Alteration of the Endometrial Lining: The combination of hormones changes the uterine lining, reducing the likelihood of implantation of a fertilized egg.

What is Balziva Used For?

  • Prevention of Pregnancy: It is primarily used as a contraceptive to prevent unwanted pregnancies.
  • Regulation of Menstrual Cycles: Balziva can help regulate irregular menstrual cycles.
  • Treatment of Acne: It may be prescribed to help manage moderate acne in women who seek contraception.


Common Dosages

Balziva is available by prescription only and is not classified as a controlled substance. The medication is typically provided in a 28-day pack, which includes 21 active hormone pills and 7 inactive (placebo) pills to be taken during the menstrual period.


Balziva is typically taken as one tablet daily at the same time each day:

  • 21 Active Pills: Containing 0.4 mg of norethindrone and 35 mcg of ethinyl estradiol.
  • 7 Inactive Pills: Containing no hormones, taken during the last week of the cycle to allow for a withdrawal bleed (menstrual period).

Typical Dosing

FDA Approved Indications

Balziva is taken once daily, starting on the first day of the menstrual cycle or the first Sunday after the onset of menstruation. It is important to take the pill at the same time each day to maintain consistent hormone levels and maximize its effectiveness. If a dose is missed, it should be taken as soon as remembered, and backup contraception may be needed depending on when the dose was missed.


Who Shouldn't Take Balziva?

Balziva is contraindicated in women with:

  • A history of thrombotic disorders, such as deep vein thrombosis (DVT) or pulmonary embolism (PE).
  • A history of stroke or heart attack.
  • Uncontrolled hypertension.
  • Known or suspected breast cancer or other estrogen- or progestin-sensitive cancers.
  • Liver disease or liver tumors.
  • Undiagnosed abnormal vaginal bleeding.
  • Known or suspected pregnancy.
  • Hypersensitivity to any component of the medication.


Advice From The Pharmacist

Patients taking Balziva should be advised to take the medication at the same time every day to ensure effectiveness. If a pill is missed, the patient should follow the instructions provided in the medication guide, which may include taking the missed pill as soon as remembered or using backup contraception. Patients should also be informed about the potential side effects and the importance of reporting any unusual symptoms, such as severe headaches, chest pain, or vision changes, which could indicate serious complications. Additionally, patients should be reminded that Balziva does not protect against sexually transmitted infections (STIs); therefore, the use of condoms is recommended for STI prevention.



Side Effects of Balziva

Common Side Effects

Common side effects of Balziva may include:

  • Nausea or vomiting
  • Breast tenderness or enlargement
  • Weight gain or fluid retention
  • Mood changes, including depression or irritability
  • Headaches, including migraines
  • Irregular menstrual bleeding (spotting or breakthrough bleeding)
  • Changes in libido


Uncommon/Severe Side Effects

Serious side effects can include:

  • Blood clots (DVT, PE)
  • Stroke or heart attack, particularly in smokers over the age of 35
  • Hypertension (high blood pressure)
  • Liver problems, such as jaundice or liver tumors

Patients should seek immediate medical attention if they experience symptoms of a blood clot (such as leg pain, swelling, or shortness of breath) or signs of liver problems (such as yellowing of the skin or eyes).



Risks and Warnings of Balziva

  • Blood Clots: The use of oral contraceptives is associated with an increased risk of venous thromboembolism, particularly in women who smoke, are overweight, or have a history of clotting disorders.
  • Cardiovascular Events: The risk of heart attack and stroke increases with age and smoking, particularly in women over 35.
  • Liver Disease: Women with a history of liver disease should use Balziva with caution, as it can exacerbate liver conditions.
  • Hypertension: Balziva may increase blood pressure; regular monitoring is advised, especially in women with a history of hypertension.

Interactions with Balziva

Common Drug Interactions

Balziva may interact with other medications, including:

  • Antibiotics and Antifungals: Some antibiotics, like rifampin, can decrease the effectiveness of Balziva.
  • Antiepileptic Drugs: Medications like phenytoin or carbamazepine can reduce the effectiveness of oral contraceptives.
  • St. John's Wort: This herbal supplement can decrease the levels of contraceptive hormones, reducing effectiveness.
  • Anticoagulants: Estrogen can alter the effects of anticoagulants like warfarin.

Patients should inform their healthcare provider of all medications, supplements, and herbal products they are taking to avoid potential interactions.



Alternatives to Balziva

Alternative contraceptive methods include:

  • Other combined oral contraceptives: There are many other brands and formulations with varying hormone levels.
  • Progestin-only pills (POPs): These are an alternative for women who cannot take estrogen.
  • Long-acting reversible contraceptives (LARCs): Such as intrauterine devices (IUDs) or contraceptive implants.
  • Barrier methods: Including condoms or diaphragms.
  • Injectable contraceptives: Such as Depo-Provera.
  • Permanent contraception: Tubal ligation or vasectomy for those seeking permanent solutions.