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Azor
Azor is a combination prescription medication containing amlodipine besylate (a calcium channel blocker) and olmesartan medoxomil (an angiotensin II receptor blocker or ARB). It is used to treat high blood pressure (hypertension) in adults. By relaxing blood vessels and preventing blood vessel constriction, Azor helps lower blood pressure, which reduces the risk of strokes, heart attacks, and kidney problems.
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Frequently Asked Questions
How long does it take for Azor to start lowering blood pressure?
Azor can begin to lower blood pressure within 1 to 2 weeks, but it may take up to 4 weeks to see the full effect.
Can I stop taking Azor if my blood pressure improves?
No, even if your blood pressure improves, you should continue taking Azor as prescribed. Stopping the medication could lead to an increase in blood pressure. Always consult your doctor before making any changes.
Can I drink alcohol while taking Azor?
Alcohol may further lower your blood pressure and increase the risk of dizziness or fainting. It’s best to limit alcohol consumption while taking Azor.
What should I do if I miss a dose of Azor?
If you miss a dose, take it as soon as you remember. If it's almost time for your next dose, skip the missed dose and take your next dose at the regular time. Do not double up doses.
Is Azor safe during pregnancy?
No, Azor is not safe during pregnancy as it can cause injury or death to the fetus. If you become pregnant while taking Azor, discontinue the medication and consult your healthcare provider immediately.
Comprehensive Drug Guide
How Does Azor Work?
- Amlodipine works by inhibiting calcium ions from entering the heart and blood vessel walls, which causes blood vessels to relax and widens them, lowering blood pressure.
- Olmesartan blocks the action of angiotensin II, a hormone that causes blood vessels to tighten. By blocking this hormone, olmesartan relaxes blood vessels, which also lowers blood pressure.
Common Dosages
- 5 mg/20 mg
- 10 mg/20 mg
- 5 mg/40 mg
- 10 mg/40 mg
Typical Dosing
- The typical starting dose is 5 mg/20 mg once daily, but the dose may be increased depending on the patient's response. The maximum dose is 10 mg/40 mg once daily.
- Azor should be taken with or without food, at the same time each day.
Typical Dosing
FDA Approved Indications
- Treatment of high blood pressure (hypertension) in adults. It can be used alone or in combination with other antihypertensive agents.
Who Shouldn't Take Azor?
- Known hypersensitivity to amlodipine, olmesartan, or any components of the medication.
- Pregnancy, as drugs that affect the renin-angiotensin system can cause injury or death to the developing fetus.
Advice From The Pharmacist
- Take Azor at the same time every day to maintain consistent blood pressure control.
- Avoid consuming grapefruit or grapefruit juice while taking Azor, as it can increase amlodipine levels in the blood, potentially leading to unwanted side effects.
- Monitor your blood pressure regularly, and inform your healthcare provider if you experience significant side effects, such as dizziness or swelling in the hands or feet.
- If you miss a dose, take it as soon as you remember, but do not double up doses.
Side Effects of Azor
Common Side Effects
- Dizziness
- Swelling of the ankles or feet (edema)
- Headache
- Fatigue
Uncommon/Severe Side Effects
- Low blood pressure (hypotension)
- Kidney problems
- Severe allergic reactions (rash, swelling, difficulty breathing)
Risks and Warnings of Azor
- Fetal toxicity: Azor should not be used during pregnancy due to the risk of injury or death to the fetus. Discontinue the drug as soon as pregnancy is detected.
- Hypotension: Patients who are volume-depleted (e.g., those on diuretics) may experience severe low blood pressure when starting Azor. Blood pressure should be monitored closely.
- Renal impairment: Azor can worsen kidney function in patients with existing kidney problems.
Interactions with Azor
Common Drug Interactions
- NSAIDs: Non-steroidal anti-inflammatory drugs (like ibuprofen) may reduce the blood pressure-lowering effects of Azor and increase the risk of kidney problems.
- Potassium supplements: Azor may increase potassium levels, so combining it with potassium supplements or potassium-sparing diuretics can lead to hyperkalemia.
- Other antihypertensives: Azor can be safely combined with other blood pressure medications but should be monitored to prevent excessive blood pressure lowering.
Alternatives to Azor
- Norvasc (amlodipine): A single-agent calcium channel blocker used for hypertension and angina.
- Benicar (olmesartan): An angiotensin II receptor blocker that can be used as a single-agent treatment for hypertension.
- Exforge (amlodipine/valsartan): Another combination of a calcium channel blocker and angiotensin II receptor blocker for hypertension treatment.
