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Aricept
Donepezil belongs to a class of medications known as cholinesterase inhibitors. It?s commonly used to manage symptoms of Alzheimer's disease such as confusion or dementia. Some frequent side effects may include nausea, diarrhea, and trouble sleeping. However, your healthcare provider will consider the benefits to outweigh these potential issues.
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Frequently Asked Questions
Can I take donepezil if I am pregnant?
If you re pregnant or planning to be, let your healthcare provider know. Although this medication has been classified as category C, meaning risk cannot be ruled out, the decision should be a combined one based on maternal needs and potential risks to the fetus.
Does donepezil have any effect on the heart?
Donepezil can cause slowed heart rate, fainting, and even heart block in some patients especially those who are prone to or have a history of cardiac diseases. Therefore, it s recommended to discuss this with your healthcare provider if you ve been diagnosed with any heart ailment.
Can I just stop giving donepezil to my loved ones if they show no signs of improvement?
Abruptly discontinuing donepezil or any other Alzheimer s medication is not recommended. Consult with the healthcare provider first. Also, remember that while donepezil can help manage symptoms, it is not a cure for Alzheimer s.
Can donepezil cause weight loss?
While this is not common, a small percentage of people taking donepezil might experience decreased appetite and weight loss. If weight loss becomes concerning, speak to your healthcare provider.
My loved one is behaving unusually agitated after starting this medication. Is this normal?
Donepezil can, in some cases, cause mood changes, including agitation. If these changes become worrisome, consult with your healthcare provider.
Comprehensive Drug Guide
How Does Aricept Work?
Donepezil is specifically designed to improve the function of nerve cells in the brain by preventing the breakdown of acetylcholine, a type of neurotransmitter that is essential for memory, attention, reasoning, and other mental functions.
What is Aricept Used For?
FDA indications: Donepezil is approved to treat all stages of Alzheimer's disease.
Off-label uses: In some cases, it has been utilized off-label to treat cognitive symptoms in conditions like Parkinson's disease, vascular dementia, and multiple sclerosis.
Common Dosages
Tablets: 5mg, 10mg, and 23mg
Typical Dosing
FDA Approved Indications
- For FDA-approved indications:
- Alzheimer's disease: Starts at 5mg per day for 4-6 weeks, after which your doctor may increase the dose to 10mg per day.
Off-Label Uses
- For off-label uses:
- The dosing varies based on the severity of the condition and is determined by the healthcare provider.
Who Shouldn't Take Aricept?
- Individuals are allergic to donepezil or any of the ingredients used in its formulation.
- Those having a history of stomach ulcers are at risk as donepezil may exacerbate this condition.
- People with heart rhythm disorders like "sick sinus syndrome" (SSS) or certain types of blockades should also veer off from this drug unless specifically advised by a doctor.
- Patients with lung diseases like asthma or COPD should take it with caution.
- Individuals with seizure disorders, difficulty urinating due to an enlarged prostate, or those with liver or kidney disease should use this drug judiciously.
Advice From The Pharmacist
- Donepezil can be taken with or without food, preferably at bedtime for optimal results.
- If you notice any new or worsening symptoms, immediately contact your healthcare provider.
- Taking this medication consistently and regularly is crucial for the best treatment outcomes.
Side Effects of Aricept
Common Side Effects
- You might experience nausea, vomiting, or diarrhea.
- You may feel tired or have a decreased appetite.
- Your sleep pattern may be disrupted.
Uncommon/Severe Side Effects
- Rare side effects:
- It might cause stomach ulcers or bleeding.
- It may cause seizures.
- You might experience urinary incontinence.
Risks and Warnings of Aricept
- Be cautious if you?re a heart patient. This drug can cause slow heart rate, fainting, or even heart block.
- Take a warning if you suffer from asthma or other obstructive pulmonary diseases. Donepezil might worsen these conditions.
- Discuss with your healthcare provider beforehand if you suffer from seizures.
- Let your healthcare provider know if you?re planning to have any kind of surgery, including dental procedures.
- Do not take this medication if you?re pregnant or breastfeeding, unless your healthcare provider specifically recommended it.
- Donepezil should be received by people with difficulty in urinating due to an enlarged prostate only after a measured decision by a healthcare provider.
- This drug is not recommended for people under the age of 18.
- Take precautions if you?re prone to developing ulcers; this drug might amplify the risk.
- If you have liver or kidney disease, discuss it with your healthcare provider before
Interactions with Aricept
Common Drug Interactions
- Ketoconazole
- Quinidine
- Dexamethasone
- Rifampin
- Phenytoin
- Carbamazepine
- Phenobarbital
Alternatives to Aricept
- Rivastigmine
- Galantamine
- Memantine
- Tacrine
