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Altabax
Altabax (generic name: retapamulin) is a topical antibiotic used for the treatment of impetigo, a highly contagious skin infection typically caused by Staphylococcus aureus or Streptococcus pyogenes. It is approved for use in patients aged 9 months and older. Altabax belongs to the pleuromutilin class of antibiotics and works by inhibiting bacterial protein synthesis, thereby preventing the growth and spread of bacteria on the skin. It is most commonly used to treat mild to moderate impetigo and other localized skin infections.
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Frequently Asked Questions
How long does it take for Altabax to work?
Most patients begin to see an improvement in symptoms within 2-3 days of starting treatment. The full course of treatment typically lasts for 5 days.
Can I use Altabax on my child?
Yes, Altabax is approved for use in children aged 9 months and older for the treatment of impetigo and other localized skin infections.
What should I do if I miss a dose of Altabax?
If you miss a dose, apply it as soon as you remember. If it is almost time for the next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not apply extra ointment to make up for the missed dose.
Can I cover the treated area with a bandage?
Yes, you can cover the area with a light dressing if needed. However, make sure the area is clean and dry before applying Altabax and the bandage.
Is Altabax effective for all types of skin infections?
Altabax is specifically approved for treating impetigo caused by Staphylococcus aureus and Streptococcus pyogenes. It may not be effective for other types of bacterial infections or fungal infections. Consult your healthcare provider for the correct treatment.
Comprehensive Drug Guide
How Does Altabax Work?
Altabax works by inhibiting bacterial protein synthesis through binding to the 50S ribosomal subunit. This prevents bacteria from producing essential proteins necessary for their growth and survival, leading to the elimination of the infection. Retapamulin is bacteriostatic at low concentrations and bactericidal at higher concentrations against the targeted bacteria.
Common Dosages
- Topical ointment: 1% retapamulin
Typical Dosing
- The usual dose of Altabax is a thin layer applied to the affected area of the skin twice daily for 5 days. The area should be covered with a dressing if needed, and hands should be washed before and after application.
Typical Dosing
FDA Approved Indications
- Treatment of impetigo caused by Staphylococcus aureus (methicillin-susceptible) and Streptococcus pyogenes in adults and children aged 9 months and older.
Who Shouldn't Take Altabax?
- Known hypersensitivity to retapamulin or any of the components in the formulation.
Advice From The Pharmacist
- Do not apply Altabax to mucous membranes, such as inside the nose, mouth, or eyes. It is intended for external use only.
- Wash the affected area before applying the ointment and avoid covering large areas of skin unless directed by a healthcare provider.
- If the infection does not improve within 3-4 days, or if it worsens, contact your healthcare provider for further evaluation.
Side Effects of Altabax
Common Side Effects
- Mild redness, irritation, or itching at the application site
- Rash
Uncommon/Severe Side Effects
- Severe allergic reactions (such as swelling, rash, or difficulty breathing)
Risks and Warnings of Altabax
- Allergic Reactions: Though rare, some individuals may experience an allergic reaction to retapamulin. If any symptoms of an allergic reaction, such as swelling, hives, or difficulty breathing occur, stop using the medication and seek medical attention immediately.
- Antibiotic Resistance: As with all antibiotics, using Altabax improperly (e.g., stopping treatment too soon) may lead to the development of antibiotic-resistant bacteria. Follow the prescribed treatment course exactly.
Interactions with Altabax
Common Drug Interactions
- Other topical treatments: There are no significant known interactions between Altabax and other topical treatments. However, you should inform your healthcare provider if you are using other skin products to avoid potential irritation or reduced efficacy.
Alternatives to Altabax
- Mupirocin (Bactroban): Another topical antibiotic commonly used to treat impetigo.
- Fusidic Acid: A topical antibiotic used in some countries to treat skin infections, including impetigo.
- Oral antibiotics: For more severe or widespread infections, oral antibiotics such as cephalexin or dicloxacillin may be prescribed.
