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AK-Poly-Bac

AK-Pol-Bac is a combination ophthalmic ointment containing two antibiotics: polymyxin B and bacitracin. This medication is primarily prescribed for treating bacterial infections of the eye, such as conjunctivitis (pink eye) and blepharitis (inflammation of the eyelids). The combination of these two antibiotics helps prevent and treat infections by inhibiting bacterial growth, making it effective against a range of gram-positive and gram-negative bacteria.


AK-Pol-Bac is available by prescription and can be found in most pharmacies as an ophthalmic ointment. It is not classified as a controlled substance, meaning it has a low potential for abuse or dependence. Patients should use it under the supervision of a healthcare provider to ensure safe and effective treatment.


AK-Pol-Bac belongs to the formal drug class of topical antibiotics. Informally, it may also be referred to as an antibacterial eye ointment. These classifications highlight its role in treating bacterial infections in the eye area.



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Frequently Asked Questions

How long should I use AK-Pol-Bac?
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Follow your healthcare provider's instructions. Typically, AK-Pol-Bac is used for 7 to 10 days, but your doctor may adjust the duration based on your condition.

Can I use AK-Pol-Bac if I wear contact lenses?
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You should remove contact lenses before applying the ointment and wait at least 15 minutes before reinserting them. It is generally recommended to avoid wearing contact lenses while treating an active eye infection.

What should I do if I miss a dose?
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Apply the missed dose as soon as you remember. If it's almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Can AK-Pol-Bac be used for other types of infections?
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AK-Pol-Bac is specifically designed for bacterial eye infections. It should not be used for viral, fungal, or non-bacterial infections without consulting a healthcare provider.

What should I do if I experience severe eye irritation after using AK-Pol-Bac?
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If you experience severe irritation or any signs of an allergic reaction, stop using the ointment immediately and contact your healthcare provider.

Comprehensive Drug Guide

How Does AK-Poly-Bac Work?

AK-Pol-Bac works by utilizing the antibacterial properties of its two active ingredients, polymyxin B and bacitracin. Polymyxin B disrupts the bacterial cell membrane of gram-negative bacteria, causing cell death. Bacitracin, on the other hand, inhibits cell wall synthesis in gram-positive bacteria, preventing bacterial growth and replication. Together, these antibiotics provide broad-spectrum coverage against various bacterial pathogens, effectively treating eye infections.



Common Dosages

AK-Pol-Bac is typically available as an ophthalmic ointment. The standard dosage involves applying a small amount of the ointment (about 1/2 inch) to the affected eye(s) 1 to 3 times daily, depending on the severity of the infection and the specific instructions from the healthcare provider.


For bacterial conjunctivitis or blepharitis, the typical dosing involves applying a small strip of ointment to the inside of the lower eyelid 1 to 3 times daily. The duration of treatment generally ranges from a few days to a week, depending on the response to the medication. It is essential to follow the dosing schedule provided by the healthcare provider and not discontinue use prematurely, even if symptoms improve.



Typical Dosing

FDA Approved Indications

AK-Pol-Bac is FDA-approved for the treatment of superficial ocular infections involving the conjunctiva and/or cornea caused by susceptible bacteria. This includes conditions such as bacterial conjunctivitis and blepharitis. Off-label uses are less common but may include other superficial bacterial infections of the eye as determined by a healthcare provider.



Who Shouldn't Take AK-Poly-Bac?

AK-Pol-Bac should not be used in individuals who are allergic to polymyxin B, bacitracin, or any other component of the ointment. Additionally, it is contraindicated in cases of viral or fungal infections of the eye, as this antibiotic ointment is ineffective against non-bacterial pathogens. Pregnant or breastfeeding women should consult their healthcare provider before using this medication.



Advice From The Pharmacist

When using AK-Pol-Bac, ensure to wash your hands thoroughly before and after application. Avoid touching the tip of the ointment tube to any surface, including the eye, to prevent contamination. Apply the ointment as prescribed, and if you wear contact lenses, remove them before applying the ointment and wait at least 15 minutes after use before reinserting them. If symptoms persist or worsen, contact your healthcare provider.



Side Effects of AK-Poly-Bac

Common Side Effects

Common side effects of AK-Pol-Bac include temporary blurred vision, eye irritation, and redness at the application site. These symptoms typically subside as the body adjusts to the medication.



Uncommon/Severe Side Effects

Serious side effects, though rare, may include severe allergic reactions, such as swelling, rash, or difficulty breathing. If you experience any severe or unusual symptoms, seek medical attention immediately.

Risks and Warnings of AK-Poly-Bac

The major risks associated with AK-Pol-Bac involve potential allergic reactions to the components of the ointment. Overuse or misuse can also lead to antibiotic resistance or worsening of the infection if not used appropriately. Patients should use this medication only as directed and avoid using it for viral or fungal infections of the eye.



Interactions with AK-Poly-Bac

Common Drug Interactions

There are no significant drug interactions reported with AK-Pol-Bac when used as directed. However, it is essential to inform your healthcare provider of all medications, supplements, and other eye treatments you are using to ensure compatibility and avoid potential interactions.



Alternatives to AK-Poly-Bac

Alternative treatments for bacterial eye infections include other antibiotic ointments or drops such as erythromycin ointment or ciprofloxacin drops. The choice of alternative treatment depends on the type of bacteria causing the infection and any known allergies or sensitivities.