You're not logged in. Please log in to earn stock or Bitcoin rewards on your prescription purchase.
Ziac
Ziac is the brand name for the combination of bisoprolol fumarate and hydrochlorothiazide. This medication is prescribed to treat high blood pressure (hypertension). Bisoprolol is a beta-blocker, which helps to lower blood pressure by reducing the heart's workload, while hydrochlorothiazide is a thiazide diuretic (water pill), which helps eliminate excess salt and water from the body through urine. Together, these two medications help manage hypertension and reduce the risk of heart attacks and strokes.
Rx. Enter your prescription
How would you like to get your prescription? Select an option
Pharmacy pickup
Select from 35,000 pharmacies
Free two-day delivery
Coming soon!
Find a pharmacy near you. Enter your ZIP code
Are you a member? Sign up or log in.
Members have saved
$NaN
using our savings card for instant savings.
Don't pay full retail price and miss out on potential savings. Try it now—you have nothing to lose!
NaNM
worth of Satoshi has been rewarded to our members.
Everyone who signs up enjoys the benefits of earning FREE Bitcoin with every purchase.
How much Bitcoin can you earn with Ziac ?
The potential for Bitcoin rewards to increase and appreciate in value is a possibility to consider, which may occur over time.
See the value of your savings today
Today's Value
1 Bitcoin = $NaN
Bitcoin (BTC)
...
USD
$NaN
Adjust Bitcoin's potential value to see how much it could be worth
Potential Value
1 Bitcoin =
Bitcoin (BTC)
...
USD
$NaN
Frequently Asked Questions
How long does it take for Ziac to lower blood pressure?
Ziac usually starts working within a few hours, but it may take a few weeks for its full effect on blood pressure to become noticeable.
Can I drink alcohol while taking Ziac?
It is best to limit alcohol while taking Ziac, as it may amplify the blood pressure-lowering effects and increase the risk of dizziness or fainting.
Should Ziac be taken with food?
Ziac can be taken with or without food, but taking it with food may help reduce the likelihood of nausea.
What should I do if I miss a dose of Ziac?
If you miss a dose, take it as soon as you remember. If it is close to your next dose, skip the missed dose and resume your regular schedule. Do not double up on doses.
Is it safe to take Ziac long-term?
Yes, Ziac is generally safe for long-term use, but regular monitoring by your healthcare provider is important to ensure it continues to be effective and safe for your condition.
Comprehensive Drug Guide
How Does Ziac Work?
Ziac works by combining the effects of bisoprolol and hydrochlorothiazide. Bisoprolol reduces the heart rate and the force of heart contractions, thereby lowering blood pressure. Hydrochlorothiazide helps reduce blood volume by increasing urine output, which decreases the amount of fluid in blood vessels, further reducing blood pressure. Together, these actions help to keep blood pressure within a normal range and reduce the risk of cardiovascular complications.
Common Dosages
- 2.5 mg/6.25 mg (2.5 mg of bisoprolol and 6.25 mg of hydrochlorothiazide)
- 5 mg/6.25 mg (5 mg of bisoprolol and 6.25 mg of hydrochlorothiazide)
- 10 mg/6.25 mg (10 mg of bisoprolol and 6.25 mg of hydrochlorothiazide)
Typical Dosing
- For hypertension: The usual starting dose is one tablet daily, with the strength tailored to the patient's blood pressure goals. The dosage may be adjusted based on the patient's response and tolerance to the medication.
Typical Dosing
FDA Approved Indications
- Hypertension (high blood pressure), which reduces the risk of stroke, heart attack, and other cardiovascular conditions.
Who Shouldn't Take Ziac?
- Severe bradycardia (slow heart rate)
- Heart block (second or third-degree) without a pacemaker
- Cardiogenic shock
- Overt cardiac failure
- Hypersensitivity to bisoprolol, hydrochlorothiazide, or sulfonamide-derived drugs
- Anuria (inability to produce urine)
Advice From The Pharmacist
- Take Ziac in the morning to avoid frequent urination at night due to the diuretic component.
- Do not suddenly stop taking Ziac without consulting your healthcare provider, as this could worsen your condition.
- Be sure to stay hydrated, but monitor your salt intake while taking Ziac, as it may affect your body's electrolyte balance.
- Regular monitoring of blood pressure, kidney function, and electrolytes is important during treatment.
- If you have diabetes, be aware that hydrochlorothiazide may raise your blood sugar levels.
Side Effects of Ziac
Common Side Effects
- Dizziness or lightheadedness
- Fatigue
- Nausea
- Increased urination
- Low blood pressure (hypotension)
Uncommon/Severe Side Effects
- Severe allergic reactions (rash, itching, swelling)
- Heart problems such as very slow heart rate (bradycardia)
- Severe electrolyte imbalances
- Worsening heart failure
Risks and Warnings of Ziac
- Heart Failure and Bradycardia: Ziac can cause or worsen heart failure and slow the heart rate significantly in some patients. Regular monitoring is essential.
- Electrolyte Imbalance: The hydrochlorothiazide component may cause low levels of potassium or sodium in the blood, leading to weakness, confusion, or heart rhythm problems.
- Severe Hypersensitivity: Allergic reactions to sulfonamide-derived drugs, including hydrochlorothiazide, can occur and may require discontinuation.
Interactions with Ziac
Common Drug Interactions
- Other blood pressure medications: Taking Ziac with other antihypertensives may increase the risk of excessively low blood pressure.
- NSAIDs (non-steroidal anti-inflammatory drugs): May reduce the effectiveness of Ziac and increase the risk of kidney problems.
- Diabetes medications: Hydrochlorothiazide may interfere with blood sugar control, requiring adjustments in diabetes treatment.
Alternatives to Ziac
- Lisinopril-HCTZ: An ACE inhibitor and diuretic combination used to treat hypertension.
- Atenolol-Chlorthalidone: Another beta-blocker and diuretic combination for managing high blood pressure.
- Metoprolol: A beta-blocker used as a standalone option for hypertension and heart issues.
