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Zerviate

Zerviate (cetirizine ophthalmic solution) is a prescription antihistamine eye drop used to treat itchy eyes caused by allergic conjunctivitis. Allergic conjunctivitis is an inflammation of the eye due to allergies, leading to itching, redness, and swelling. Zerviate helps relieve these symptoms by blocking histamine, a substance in the body that triggers allergic reactions.

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Frequently Asked Questions

How long does it take for Zerviate to start working?
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Zerviate typically starts relieving itchy eyes caused by allergies within minutes of application, though full relief may take a few hours.

Can I use Zerviate with other allergy medications?
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Yes, Zerviate can be used alongside other allergy medications, such as oral antihistamines. However, always consult your healthcare provider before combining treatments.

Can Zerviate be used long-term?
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Zerviate is safe for long-term use during allergy seasons or as needed to control symptoms of allergic conjunctivitis. Follow your healthcare provider’s instructions regarding duration of use.

Can I use Zerviate more than twice a day?
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No, you should not exceed the recommended dose of two drops per day (one in each eye twice daily). Using more than directed may increase the risk of side effects without providing additional relief.

What should I do if I miss a dose of Zerviate?
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If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular schedule. Do not apply extra drops to make up for a missed dose.

Comprehensive Drug Guide

How Does Zerviate Work?

Zerviate contains cetirizine, an antihistamine that works by blocking H1 receptors in the eye. This prevents histamine from binding to these receptors and triggering the allergic response that causes eye itching, redness, and inflammation. By inhibiting histamine, Zerviate helps alleviate the symptoms of allergic conjunctivitis.

Common Dosages

  • One drop in each affected eye twice daily (approximately every 8-12 hours).

Typical Dosing

  • For itchy eyes due to allergic conjunctivitis: Apply one drop of Zerviate into each affected eye twice daily (every 8 to 12 hours). Do not exceed two doses per day.

Typical Dosing

FDA Approved Indications

  • Ocular itching associated with allergic conjunctivitis.

Who Shouldn't Take Zerviate?

  • Known hypersensitivity to cetirizine or any other components of the formulation.

Advice From The Pharmacist

  • Wash your hands before applying Zerviate to avoid contamination.
  • Tilt your head back, pull down the lower eyelid, and apply one drop of Zerviate into the affected eye. Be careful not to touch the dropper tip to your eye or any surface to prevent contamination.
  • If you wear contact lenses, remove them before using Zerviate and wait at least 10 minutes before reinserting them, as the solution contains preservatives that may irritate the lenses.
  • If you are using other eye drops, wait at least 5 minutes between applying different products.
  • Store Zerviate at room temperature, away from direct light and moisture.

Side Effects of Zerviate

Common Side Effects

  • Eye redness
  • Eye irritation, such as burning or stinging upon application
  • Blurred vision immediately after using the drops
  • Headache

Uncommon/Severe Side Effects

  • Severe allergic reactions, such as swelling, hives, or difficulty breathing
  • Increased eye discomfort or worsening of symptoms

Risks and Warnings of Zerviate

  • Eye Irritation: Some patients may experience mild eye irritation, such as burning or stinging, immediately after applying Zerviate. If the irritation persists or worsens, contact your healthcare provider.
  • Contact Lenses: Zerviate contains preservatives that may irritate contact lenses. Always remove contact lenses before using the drops and wait at least 10 minutes before reinserting them.
  • Contamination Risk: Be careful not to touch the tip of the dropper to any surface, including your eye, to avoid contamination that could lead to an eye infection.

Interactions with Zerviate

Common Drug Interactions

  • There are no known significant drug interactions with Zerviate due to its local administration in the eyes. However, inform your healthcare provider about any other eye medications or treatments you are using to ensure compatibility.

Alternatives to Zerviate

  • Patanol (olopatadine): Another antihistamine eye drop used to treat allergic conjunctivitis.
  • Zaditor (ketotifen): An over-the-counter antihistamine eye drop for relieving itchy eyes caused by allergies.
  • Alaway (ketotifen): Another over-the-counter eye drop for allergy-related eye itching and discomfort.