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Xelpros
Xelpros (generic name: latanoprost ophthalmic emulsion) is a prescription eye drop used to reduce elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension. It helps lower the pressure in the eye, which can reduce the risk of damage to the optic nerve and prevent vision loss. Xelpros is a prostaglandin analog, and it works by increasing the outflow of aqueous humor, the fluid inside the eye, to lower the pressure.
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Frequently Asked Questions
How long does it take for Xelpros to start lowering eye pressure?
Xelpros typically begins to lower intraocular pressure within 3 to 4 hours after administration, with the maximum effect occurring 8 to 12 hours after use.
Can I use Xelpros while wearing contact lenses?
No, you should remove your contact lenses before applying Xelpros, as the preservatives in the eye drops can be absorbed by soft contact lenses. Wait at least 15 minutes after using the drops before reinserting your lenses.
What should I do if I miss a dose of Xelpros?
If you miss a dose of Xelpros, apply it as soon as you remember. However, if it’s close to the time for your next dose, skip the missed dose and resume your regular schedule. Do not double the dose to make up for the missed one.
Can Xelpros change the color of my eyes?
Yes, Xelpros can cause a permanent change in eye color, particularly in patients with lighter-colored eyes. This occurs due to increased pigmentation of the iris and may not be reversible.
Can I use Xelpros more than once a day?
No, Xelpros should only be used once daily. Using it more frequently may reduce its effectiveness in lowering intraocular pressure.
Comprehensive Drug Guide
How Does Xelpros Work?
Xelpros works by increasing the outflow of aqueous humor from the eye, which helps to lower intraocular pressure. Elevated IOP is a major risk factor for glaucoma, and by reducing this pressure, Xelpros helps to prevent further optic nerve damage and protect vision.
What is Xelpros Used For?
Common Dosages
- 0.005% ophthalmic emulsion (eye drops)
Typical Dosing
- The typical dose is one drop in the affected eye(s) once daily, preferably in the evening. Do not exceed once-daily dosing, as more frequent administration may reduce the effectiveness of the medication.
Typical Dosing
FDA Approved Indications
- Reducing intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension.
Who Shouldn't Take Xelpros?
- Known hypersensitivity to latanoprost or any component of the formulation.
Advice From The Pharmacist
- Administer Xelpros in the evening, as it is most effective when applied before bedtime.
- Remove contact lenses before using Xelpros, and wait at least 15 minutes before reinserting them.
- Wash your hands before using the eye drops, and avoid touching the tip of the dropper to your eye or any surface to prevent contamination.
- If using multiple eye drops, wait at least 5 minutes between different medications.
Side Effects of Xelpros
Common Side Effects
- Eye redness
- Blurred vision
- Eye discomfort
- Increased pigmentation of the iris (may cause darkening of eye color)
- Eyelash growth and thickening
Uncommon/Severe Side Effects
- Eye infection (pain, swelling, discharge)
- Changes in vision
Risks and Warnings of Xelpros
- Iris Pigmentation: Xelpros can cause permanent changes in eye color, particularly in individuals with lighter-colored eyes. This occurs due to increased pigmentation in the iris and may not be reversible.
- Eyelash Changes: Xelpros may cause increased growth and thickening of eyelashes. These changes are reversible upon discontinuation of the medication.
- Contact Lens Use: Xelpros contains preservatives that can be absorbed by soft contact lenses. Remove contact lenses before applying the drops and wait at least 15 minutes before reinserting them.
Interactions with Xelpros
Common Drug Interactions
- Other eye drops: If using other ophthalmic medications, apply them at least 5 minutes apart to avoid washout or reduced effectiveness.
Alternatives to Xelpros
- Latanoprost (Xalatan): A similar prostaglandin analog used to reduce IOP in patients with glaucoma or ocular hypertension.
- Travoprost (Travatan Z): Another prostaglandin analog used for reducing IOP.
- Bimatoprost (Lumigan): Another medication in the same class used to treat elevated IOP and glaucoma.
