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Wera
Wera is an oral contraceptive that combines two hormones, norethindrone (a progestin) and ethinyl estradiol (an estrogen), to prevent pregnancy. It works by inhibiting ovulation, thickening cervical mucus to prevent sperm from reaching the egg, and altering the lining of the uterus to prevent implantation. Wera is also used to regulate menstrual cycles, treat acne, and reduce symptoms of hormonal imbalances, such as painful periods or heavy menstrual bleeding.
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Frequently Asked Questions
How effective is Wera at preventing pregnancy?
Wera is over 99% effective when taken as directed. Missing pills or taking them inconsistently may reduce its effectiveness.
Can Wera cause weight gain?
Some women may experience minor weight changes, often related to fluid retention or hormonal fluctuations, but significant weight gain is uncommon.
What should I do if I miss a dose of Wera?
If you miss one active pill, take it as soon as you remember. If you miss more than one pill, follow the instructions in the package and use backup contraception for the next 7 days.
Can I take Wera if I smoke?
Smoking increases the risk of serious cardiovascular side effects, especially in women over 35. It is not recommended to smoke while using Wera or any other hormonal contraceptive.
Does Wera help with acne?
Yes, Wera may help reduce acne in women seeking contraception by regulating hormone levels that contribute to acne.
Comprehensive Drug Guide
How Does Wera Work?
Wera works by preventing ovulation through the action of norethindrone, which suppresses the release of luteinizing hormone (LH), and ethinyl estradiol, which suppresses follicle-stimulating hormone (FSH). Together, these hormones prevent the release of an egg from the ovaries. Additionally, the hormones thicken the cervical mucus, making it harder for sperm to enter the uterus, and alter the uterine lining to make it less suitable for implantation.
Common Dosages
- 21 active tablets with 1 mg norethindrone and 35 mcg ethinyl estradiol
- 7 placebo tablets without active hormones
Typical Dosing
- Take one active pill daily for 21 days, followed by one placebo pill daily for 7 days. During the placebo week, withdrawal bleeding occurs, mimicking a natural menstrual cycle.
Typical Dosing
FDA Approved Indications
- Prevention of pregnancy
- Regulation of menstrual cycles
- Reduction of acne in women seeking contraceptive benefits
- Treatment of hormonal imbalances, including heavy or painful periods
Who Shouldn't Take Wera?
- A history of blood clots, stroke, or heart attack
- Known or suspected breast cancer or other hormone-sensitive cancers
- Liver disease or liver tumors
- Uncontrolled hypertension
- Known hypersensitivity to norethindrone, ethinyl estradiol, or any other components of the formulation
Advice From The Pharmacist
- Take Wera at the same time every day to maintain its effectiveness. Missing doses increases the risk of pregnancy.
- If you miss a pill, take it as soon as you remember. If you miss more than one, follow the instructions in the package and use backup contraception for 7 days.
- Wera does not protect against sexually transmitted infections (STIs). Consider using condoms for STI protection.
- Certain medications, such as antibiotics and anticonvulsants, may reduce the effectiveness of Wera. Inform your healthcare provider about any other medications or supplements you are taking.
Side Effects of Wera
Common Side Effects
- Nausea
- Headache
- Breast tenderness
- Mood swings
- Weight fluctuations
Uncommon/Severe Side Effects
- Blood clots (deep vein thrombosis, pulmonary embolism)
- Stroke or heart attack
- Liver problems (jaundice, elevated liver enzymes)
Risks and Warnings of Wera
- Smoking Risk: Smoking while using Wera, especially in women over 35, increases the risk of serious cardiovascular events such as heart attack, stroke, or blood clots.
- Blood Clot Risk: Combination oral contraceptives like Wera can increase the risk of blood clots, particularly in women with risk factors such as obesity, prolonged immobility, or a family history of clotting disorders.
- Breast Cancer: Women with a personal or family history of breast cancer should consult their healthcare provider about the risks of using hormonal contraceptives like Wera.
Interactions with Wera
Common Drug Interactions
- Antibiotics: Certain antibiotics, such as rifampin, may reduce the effectiveness of Wera, increasing the risk of pregnancy. Backup contraception should be used during antibiotic treatment.
- Anticonvulsants: Medications for seizure disorders may interfere with Wera’s effectiveness.
- St. John’s Wort: This herbal supplement can reduce the effectiveness of hormonal contraceptives, including Wera.
Alternatives to Wera
- Ortho-Novum (norethindrone/ethinyl estradiol): Another combination oral contraceptive with a similar hormone profile.
- Junel Fe (norethindrone acetate/ethinyl estradiol): A low-dose combination oral contraceptive.
- Depo-Provera (medroxyprogesterone): A long-acting injectable contraceptive.
- Mirena (levonorgestrel): An intrauterine device (IUD) that provides long-term contraception.
