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Velivet
Velivet is a combined oral contraceptive pill that contains two hormones: desogestrel (a progestin) and ethinyl estradiol (an estrogen). It is used to prevent pregnancy by inhibiting ovulation, thickening cervical mucus to prevent sperm from reaching the egg, and altering the uterine lining to prevent implantation. Velivet is also sometimes prescribed to regulate menstrual cycles, reduce menstrual cramps, and treat acne.
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Frequently Asked Questions
How effective is Velivet at preventing pregnancy?
Velivet is 99% effective when taken exactly as directed, but with typical use (including missed pills), it is about 91% effective.
Can Velivet help with acne?
Yes, Velivet can help improve acne in some women by regulating hormones that can cause acne flare-ups.
What should I do if I miss a dose of Velivet?
If you miss one active pill, take it as soon as you remember, then take the next pill at the usual time. If you miss two or more pills, consult the package insert or your healthcare provider for specific instructions, and use backup contraception.
Can Velivet cause weight gain?
Some women may experience weight gain while taking Velivet, but this is usually mild and due to water retention rather than fat gain.
Can Velivet be used by smokers?
Velivet should not be used by women over the age of 35 who smoke, due to an increased risk of serious cardiovascular side effects, such as heart attack, stroke, and blood clots.
Comprehensive Drug Guide
How Does Velivet Work?
- Inhibiting ovulation by suppressing the release of the hormones responsible for egg development and release.
- Thickening cervical mucus, making it harder for sperm to travel to the egg.
- Altering the uterine lining, making it less suitable for a fertilized egg to implant.
Common Dosages
- 21 active pills containing desogestrel (0.1 mg) and ethinyl estradiol (0.02 mg) for the first 7 days, followed by 0.075 mg desogestrel/0.03 mg ethinyl estradiol for the next 7 days, and 0.125 mg desogestrel/0.025 mg ethinyl estradiol for the final 7 days.
- 7 inactive (placebo) pills taken during the last week to allow for withdrawal bleeding.
Typical Dosing
- Take one active pill daily for 21 days, followed by 7 inactive pills during the last week.
- Start a new pack immediately after finishing the 28-day cycle, with no gap between packs.
Typical Dosing
FDA Approved Indications
- Contraception (prevention of pregnancy).
- Regulating menstrual cycles.
- Reducing menstrual cramps.
- Treating acne (off-label use).
Who Shouldn't Take Velivet?
- History of blood clots (e.g., deep vein thrombosis, pulmonary embolism).
- Certain heart conditions (e.g., uncontrolled high blood pressure, stroke, coronary artery disease).
- Liver disease or liver tumors.
- Known or suspected pregnancy.
- Breast cancer or other hormone-sensitive cancers.
- Smokers over the age of 35 (due to increased risk of cardiovascular events).
Advice From The Pharmacist
- Take Velivet at the same time every day to maintain its effectiveness and reduce the risk of missing a dose.
- If you miss a pill, follow the instructions in the package insert for how to handle missed doses. Missing pills can reduce the effectiveness of the contraceptive.
- Use a backup form of contraception (e.g., condoms) if you miss more than one active pill, especially if it occurs early in the pack.
- Velivet does not protect against sexually transmitted infections (STIs), so using condoms is recommended for STI prevention.
- Store the pills at room temperature and keep them away from moisture and heat.
Side Effects of Velivet
Common Side Effects
- Nausea
- Breast tenderness
- Headache
- Weight gain
- Mood changes
- Breakthrough bleeding or spotting (especially in the first few months)
Uncommon/Severe Side Effects
- Blood clots (deep vein thrombosis, pulmonary embolism).
- Heart attack or stroke (especially in smokers over 35 years old).
- Severe allergic reactions (rash, itching, swelling, difficulty breathing).
Risks and Warnings of Velivet
- Cardiovascular Risk: Smoking increases the risk of serious cardiovascular side effects (e.g., heart attack, stroke, blood clots) when using hormonal contraceptives, particularly in women over the age of 35. Smokers should not use Velivet.
- Blood Clots: Hormonal contraceptives like Velivet increase the risk of blood clots, especially in women with a history of blood clot disorders or those who are immobile for long periods (e.g., after surgery).
- Breast Cancer Risk: There is a small increased risk of developing breast cancer in women who use hormonal contraceptives, particularly with prolonged use. Regular breast exams and screenings are advised.
Interactions with Velivet
Common Drug Interactions
- Antibiotics (e.g., rifampin): Certain antibiotics may decrease the effectiveness of Velivet.
- Anticonvulsants (e.g., phenytoin, carbamazepine): These medications can reduce the effectiveness of hormonal contraceptives.
- St. John’s Wort: This herbal supplement may reduce the effectiveness of Velivet and increase the risk of breakthrough bleeding.
Alternatives to Velivet
- Other combined oral contraceptives (COCs): There are many other brands of combined oral contraceptives that contain different types of progestin or estrogen.
- Progestin-only pills (POPs): For women who cannot take estrogen, progestin-only pills may be an alternative.
- Non-hormonal methods: Copper intrauterine devices (IUDs) and condoms provide contraception without hormones.
