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Vaxneuvance
Vaxneuvance (generic name: pneumococcal 15-valent conjugate vaccine) is a vaccine used to help protect against infections caused by Streptococcus pneumoniae, a bacterium that can lead to pneumococcal diseases such as pneumonia, meningitis, and sepsis. Vaxneuvance provides immunity by stimulating the body to produce antibodies against 15 different strains of the pneumococcus bacteria. It is recommended for both adults and children, particularly those at higher risk for pneumococcal infections.
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Frequently Asked Questions
How long does Vaxneuvance provide protection?
Vaxneuvance offers long-term protection against pneumococcal disease. The exact duration of immunity is not yet fully known but is expected to be several years after vaccination.
Can Vaxneuvance be given with other vaccines?
Yes, Vaxneuvance can be administered with other vaccines, such as the influenza vaccine, but each should be injected at a different site.
What if I’ve already received another pneumococcal vaccine?
If you've received a previous pneumococcal vaccine, such as Prevnar 13 or Pneumovax 23, Vaxneuvance can still be administered to broaden protection. Your healthcare provider will determine the appropriate timing.
Is Vaxneuvance safe for children?
Yes, Vaxneuvance is approved for children aged 6 weeks and older. It is safe and effective in reducing the risk of pneumococcal disease in pediatric patients.
Do I need a booster dose of Vaxneuvance?
Most patients do not need a booster dose after the initial series, but your healthcare provider may recommend additional doses based on your age, health conditions, and risk factors.
Comprehensive Drug Guide
How Does Vaxneuvance Work?
Vaxneuvance contains components from 15 different strains of Streptococcus pneumoniae, which are conjugated to a carrier protein. This stimulates the immune system to recognize these bacterial strains and produce protective antibodies. These antibodies help prevent future infections by these pneumococcal bacteria.
Common Dosages
- Single-dose vials for intramuscular injection.
The exact number of doses and timing will depend on the individual’s age and vaccination history.
Typical Dosing
- For adults aged 18 and older: A single dose is typically administered, but the dosing schedule may vary if the patient is receiving it alongside other pneumococcal vaccines.
- For children and infants: The typical pediatric vaccination schedule starts at 6 weeks of age and may involve a series of doses depending on age and risk factors.
Typical Dosing
FDA Approved Indications
- Adults aged 18 and older
- Pediatric patients aged 6 weeks through 17 years
Who Shouldn't Take Vaxneuvance?
- Severe allergic reactions (e.g., anaphylaxis) to any component of the vaccine or a previous dose of pneumococcal vaccine.
Advice From The Pharmacist
- Get vaccinated on schedule: Vaxneuvance is recommended for children, older adults, and people with certain health conditions that put them at higher risk of pneumococcal infections. Follow your healthcare provider’s schedule for receiving the vaccine.
- Possible mild reactions: After receiving the vaccine, you may experience mild side effects like redness, swelling, or soreness at the injection site. Other common effects include fatigue or mild fever.
- Avoid vaccination if you are ill: If you have a moderate or severe illness (e.g., fever), it’s best to wait until you recover before getting Vaxneuvance.
Side Effects of Vaxneuvance
Common Side Effects
- Pain, swelling, or redness at the injection site
- Fatigue
- Headache
- Muscle pain
- Mild fever
Uncommon/Severe Side Effects
- Severe allergic reactions (e.g., hives, swelling, difficulty breathing)
- Fainting (related to the injection process)
Risks and Warnings of Vaxneuvance
- Allergic Reactions: Like all vaccines, Vaxneuvance can cause allergic reactions, although these are rare. Seek immediate medical attention if you experience symptoms such as hives, difficulty breathing, or swelling of the face or throat.
- Fever and Irritability in Infants: Children may experience fever or irritability after receiving the vaccine. These symptoms are typically mild and resolve on their own.
Interactions with Vaxneuvance
Common Drug Interactions
- Other vaccines: Vaxneuvance can be administered alongside other vaccines, including influenza vaccines, but should be given at different injection sites if administered concurrently.
- Immunosuppressive medications: Medications that suppress the immune system may reduce the effectiveness of Vaxneuvance. Discuss any ongoing treatments with your healthcare provider.
Alternatives to Vaxneuvance
- Prevnar 13 (pneumococcal 13-valent conjugate vaccine): A similar vaccine that protects against 13 strains of Streptococcus pneumoniae.
- Pneumovax 23 (pneumococcal polysaccharide vaccine): Protects against 23 pneumococcal strains but is not conjugated and may be less effective in children under 2 years of age.
- Synflorix: Another pneumococcal conjugate vaccine used in pediatric populations.
